Results 231 to 240 of about 329,086 (345)

An alternative mechanism by which If1 prevents ATP hydrolysis by the ATP synthase subcomplex in S. cerevisiae. [PDF]

EMBO Rep
Lerouley O, Larrieu I, Ducrocq TL, Pinson B, Giraud MF, Mourier A.   +5 more
europepmc   +1 more source

The c ₁₅ ring of the Spirulina platensis F‐ATP synthase: F ₁ /F ₀ symmetry mismatch is not obligatory

, 2005
Denys Pogoryelov, Jinshu Yu, Thomas Meier, Janet Vonck, Peter Dimroth, Daniel J. Müller   +5 more
openalex   +1 more source

Irradiated Tumor Cell‐Derived Microparticles Activate Systemic Anti‐Tumor Immunity via the STING/NLRP3/GSDMD Axis in Neutrophils

Advanced Science, EarlyView.
Radiotherapy induces tumor cells to release microparticles (RT‐MPs) into the circulation. The mitochondrial DNA carried by these RT‐MPs activates the STING/NLRP3/GSDMD axis in splenic neutrophils, triggering IL‐1β secretion. This, in turn, enhances dendritic cell function and facilitates the formation of cytotoxic T lymphocytes, thereby promoting ...
Yan Hu, Jiacheng Wang, Mengjie Che, Zheng Yang, Jingshu Meng, Xiao Yang, Yue Deng, Zhiyuan Zhou, Yijun Wang, Wenwen Wei, Zhanjie Zhang, Bian Wu, You Qin, Kunyu Yang, Honglin Jin, Fang Huang, Yajie Sun, Lu Wen, Chao Wan   +18 more
wiley   +1 more source

IgA2 ACPA Drives a Hyper-Inflammatory Phenotype in Macrophages via ATP Synthase and COX2. [PDF]

Eur J Immunol
Almeida L, Bacon A, Ghorasaini M, van der Ham AJ, Toes REM, Giera M, Everts B.   +6 more
europepmc   +1 more source

Proton gradient across the chloroplast thylakoid membrane governs the redox regulatory function of ATP synthase [PDF]

Takatoshi Sekiguchi, Keisuke Yoshida, Ken‐ichi Wakabayashi, Toru Hisabori   +3 more
openalex   +1 more source

Forsythoside E Alleviates Liver Injury by Targeting PKM2 Tetramerization to Promote Macrophage M2 Polarization

Advanced Science, EarlyView.
Here, the study shows for the first time that Forsythoside E (FE) can promote PKM2 tetramerization by binding to its K311 site. Furthermore, it induces metabolic reprogramming of macrophages and inhibits NLRP3 expression. Finally, it can alleviate sepsis‐induced liver injury by promoting M2 anti‐inflammatory polarization.
Bingxin Wu, Xuechun Yu, Yanling Li, Lin An, Rongrong Zhang, Rong Zhang, Fan Zhang, Zhongqiu Liu, Caiyan Wang   +8 more
wiley   +1 more source

The chimeric gene orf610a reduces cotton pollen fertility by impairing the assembly of ATP synthase. [PDF]

Plant Biotechnol J
Han Y, Ge L, Feng J, Zhang M, Zhang H, Shi L, Wu D, Zhang X, Guo L, Qi T, Tang H, Qiao X, Xing C, Wu J.   +13 more
europepmc   +1 more source

Targeting Lactate and Lactylation in Cancer Metabolism and Immunotherapy

Advanced Science, EarlyView.
Lactate, once deemed a metabolic waste, emerges as a central regulator of cancer progression. This review elucidates how lactate and its epigenetic derivative, protein lactylation, orchestrate tumor metabolism, immune suppression, and therapeutic resistance.
Jiajing Gong, Yuhang Xie, Zhijie Weng, Yongzhi Wu, Longjiang Li, Bo Li   +5 more
wiley   +1 more source

ATP synthase complex from bovine heart mitochondria. Subunit arrangement as revealed by nearest neighbor analysis and susceptibility to trypsin.

, 1990
Saroj Joshi, Robert B. Burrows
openalex   +1 more source

Targeting DNA‐LNPs to Endothelial Cells Improves Expression Magnitude, Duration, and Specificity

Advanced Science, EarlyView.
Attaching antibodies against endothelial cell surface proteins redirects the delivery and expression of DNA‐lipid nanoparticles to organs of interest. Our targeted nanoparticles enable organ‐selective DNA expression in the endothelium of the lungs, brain, or spleen, providing a therapeutic platform for dozens of endothelial‐centric diseases.
Nicolas Marzolini, Taylor V. Brysgel, Ryan J. Rahman, Eno‐Obong Essien, Saw Y. Nwe, Jichuan Wu, Aparajeeta Majumder, Manthan N. Patel, Sachchidanand Tiwari, Carolann L. Espy, Fengyi Dong, Sabrina A. Santos‐De León, Anit Shah, Vladimir V. Shuvaev, Elizabeth D. Hood, Liam S. Chase, Drew Weissman, Jeremy B. Katzen, David B. Frank, Mariko L. Bennett, Oscar A. Marcos‐Contreras, Jacob W. Myerson, Vladimir R. Muzykantov, Sahily Reyes‐Esteves, Jacob S. Brenner   +24 more
wiley   +1 more source