Results 241 to 250 of about 837,065 (393)

Biosynthesis of H2S and Siderophores Targeting Gram‐Negative Bacterial Resistance to Reactive Oxygen Species

open access: yesAdvanced Science, EarlyView.
Discover how Gram‐negative bacteria develop resistance to reactive oxygen species, and how scientists aim to overcome this challenge. Abstract Reactive oxygen species (ROS) are a promising alternative bactericide. However, it is questioned that bacteria can potentially develop resistance to ROS, similar to their resistance against antibiotics and ...
Congyang Mao   +9 more
wiley   +1 more source

Dynamics of Adaptive Microevolution of Hypermutable Pseudomonas aeruginosa during Chronic Pulmonary Infection in Patients with Cystic Fibrosis [PDF]

open access: yes, 2009
Eichner, Anja   +7 more
core   +1 more source

Synthesis and Evaluation of Pyridine-Based Antibacterial Agents that Inhibit ATP Synthase in <i>Acinetobacter baumannii</i>. [PDF]

open access: yesACS Omega
Dennison AL   +12 more
europepmc   +1 more source

Elevated Apolipoprotein E Expression in Hippocampal Microglia Drives Temporal Lobe Epilepsy Progression

open access: yesAdvanced Science, EarlyView.
In temporal lobe epilepsy, hippocampal APOE is markedly upregulated predominantly in microglia. APOE overexpression in microglia drives TLR4 and cGAS/STING‐dependent neuroinflammation, engages bidirectional crosstalk with neurons and astrocytes, increases neuronal excitability, and perturbs hippocampal lipid metabolism. These findings suggest that APOE‐
Jianwei Shi   +10 more
wiley   +1 more source

Structures of rotary ATP synthase from <i>Thermus thermophilus</i> during proton powered ATP synthesis. [PDF]

open access: yesSci Adv
Nakano A   +8 more
europepmc   +1 more source

Topology of subunit a of the Escherichia coli ATP synthase [PDF]

open access: bronze, 1998
Heike Jäger   +4 more
openalex   +1 more source

Muscle Organoids Reveal Exercise‐Like Contractions Rapidly Promote Muscle Health Via Lamtor1's Signaling to Both AMPK and mTOR

open access: yesAdvanced Science, EarlyView.
This study develops a novel 3D human skeletal muscle organoid platform to study the immediate molecular effects of exercise‐like contractions. The model uncovers rapid proteomic and transcriptomic responses, resolving a fundamental paradox by demonstrating how exercise‐induced Lamtor1 coordinately activates both AMPK and mTORC1. Lamtor1 is a compelling
Ziyue Yao   +9 more
wiley   +1 more source

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