Results 11 to 20 of about 159,279 (352)

MicroRNA-Attenuated Virus Vaccines [PDF]

Non-Coding RNA, 2018
Live-attenuated vaccines are the most effective way to establish robust, long-lasting immunity against viruses. However, the possibility of reversion to wild type replication and pathogenicity raises concerns over the safety of these vaccines. The use of
Elizabeth J. Fay, Ryan A. Langlois
doaj   +3 more sources

Attenuated Measles Vaccine [PDF]

Nature, 1962

openalex   +2 more sources

Rational Development of Live-Attenuated Zika Virus Vaccines

Pathogens, 2023
Zika virus (ZIKV), a re-emerging mosquito-borne flavivirus, has caused outbreaks in Africa, Asia, the Pacific, and, more recently, in the Americas. ZIKV has been associated with the neurological autoimmune disorder Guillain–Barre syndrome in adults and ...
Awadalkareem Adam, Christy Lee, Tian Wang   +2 more
doaj   +1 more source

Genomic variations associated with attenuation in Mycobacterium avium subsp paratuberculosis vaccine strains [PDF]

, 2013
BACKGROUND: Mycobacterium avium subspecies paratuberculosis (MAP) whole cell vaccines have been widely used tools in the control of Johne's disease in animals despite being unable to provide complete protection. Current vaccine strains derive from stocks
Bull, TJ, Greene, M, Linedale, R, McKendrick, IJ, Sales, J, Schock, A, Sharp, JM, Stevenson, K   +7 more
core   +1 more source

Multiple potential recombination events among Newcastle disease virus genomes in China between 1946 and 2020

Frontiers in Veterinary Science, 2023
IntroductionNewcastle Disease Virus (NDV) is a highly adaptable virus with large genetic diversity that has been widely studied for its oncolytic activities and potential as a vector vaccine.
Amina Nawal Bahoussi, Pir Tariq Shah, Jia-Qi Zhao, Pei-Hua Wang, Yan-Yan Guo, Changxin Wu, Changxin Wu, Changxin Wu, Changxin Wu, Li Xing, Li Xing, Li Xing, Li Xing   +12 more
doaj   +1 more source

Safety of measles-containing vaccines in post-marketing surveillance in Anhui, China. [PDF]

PLoS ONE, 2017
The safety of measles vaccination is of great interest and importance to public health practice and the general society. We have analyzed the adverse events following immunization (AEFIs) of currently used measles-containing vaccines (including live ...
Fan-Ya Meng, Yong Sun, Yong-Gang Shen, Hai-Feng Pan, Ji-Hai Tang, Bin-Bing Wang, Chang-Hao Wu, Dong-Qing Ye   +7 more
doaj   +1 more source

The Safety and Protective Efficacy Evaluation of an Attenuated M. bovis–BoHV-1 Bivalent Vaccine in Rabbits

Vaccines, 2023
Bovine respiratory disease (BRD) is a global prevalent multifactorial infection primarily caused by viral and bacterial coinfections. In China, Mycoplasma bovis (M.
Sen Zhang, Yisheng Zhang, Guoxing Liu, Chen Wang, Yan Ji, Jianguo Chen, Changmin Hu, Xi Chen, Aizhen Guo, Yingyu Chen   +9 more
doaj   +1 more source

Vaccination with DNA plasmids expressing Gn coupled to C3d or alphavirus replicons expressing Gn protects mice against rift valley fever virus [PDF]

, 2010
Background: Rift Valley fever (RVF) is an arthropod-borne viral zoonosis. Rift Valley fever virus (RVFV) is an important biological threat with the potential to spread to new susceptible areas. In addition, it is a potential biowarfare agent. Methodology/
A Jouan, A Zaki, B Botros, BH Bird, BS Peters, CS Schmaljohn, CS Schmaljohn, Daniel G. Bausch, DB Wallace, DV Lim, FR Toapanta, FR Toapanta, G Lorenzo, GF Meadors 3rd, H Caplen, I Watanabe, J Lubroth, J Meegan, J Naslund, J Naslund, JA Mitchell, JF Bower, JF Bower, JR Haynes, JT van Oirschot, K Keegan, K Spik, KA Hubbard, M Mkrtichyan, MA Kutzler, Mark T. Heise, MT Heise, N Lagerqvist, Nitin Bhardwaj, P Hunter, P Jansen van Vuren, P Nguku, P Pittman, P Pushko, P Vialat, PR Pittman, PW Dempsey, R Gorchakov, R Gorchakov, R Randall, RJ Daubney, S Won, SA Kamal, SR Gerrard, SR Gerrard, T Shoemaker, TA Madani, TD Green, Ted M. Ross, TM Pertmer, TM Pertmer, TM Ross, TM Ross, UB Balasuriya   +58 more
core   +4 more sources

Comparative Study of the Temperature Sensitive, Cold Adapted and Attenuated Mutations Present in the Master Donor Viruses of the Two Commercial Human Live Attenuated Influenza Vaccines

Viruses, 2019
Influenza viruses cause annual, seasonal infection across the globe. Vaccination represents the most effective strategy to prevent such infections and/or to reduce viral disease.
Laura Rodriguez, Pilar Blanco-Lobo, Emma C. Reilly, Tatsuya Maehigashi, Aitor Nogales, Andrew Smith, David J. Topham, Stephen Dewhurst, Baek Kim, Luis Martínez-Sobrido   +9 more
doaj   +1 more source

Neutropenia as an adverse event following vaccination : results from randomized clinical trials in healthy adults and systematic review [PDF]

, 2016
Background : In the context of early vaccine trials aimed at evaluating the safety profile of novel vaccines, abnormal haematological values, such as neutropenia, are often reported.
Aerssens, Annelies, Anemona, Alessandra, Bodinham, Caroline L, Groth, Nicola, Launay, Odile, Leroux-Roels, Geert, Lewis, David, Loulergue, Pierre, Muturi-Kioi, Vincent, Podda, Audino, Saul, Allan   +10 more
core   +4 more sources