Results 201 to 210 of about 159,279 (352)

Construction and Validation of a Preoperative Surgical Difficulty Prediction and Risk Stratification System for Posterior Spinal Deformity Correction Surgery Based on Machine Learning ‐ Multicenter Cohort Study

iMetaMed, EarlyView.
A web calculator, trained on multicenter data with seven Boruta‐selected preoperative features, predicts prolonged operative time for posterior spinal deformity correction to enable individualized planning and optimized operating‐room resources. ABSTRACT Operative duration reflects surgical complexity and is valuable for perioperative planning.
Chan Xu, Jialiang Zheng, Chengliang Yin, Runmin Li, Xubin Quan, Binghao Chen, Zhaohui Hu, Tongqing Luo, Hao Jiang, Xuewen Hou, Qizhong Xu, Weiheng He, Liang Chen, Anfa Chen, Xin Zhou, Wei Huang, Sen Gao, Jiali Yu, Zhi‐Ri Tang, Yusi Zhang, Kai Wang, Shi‐Nan Wu, Wencai Liu, Xiangdong Xi, Haizhen Ding, Qiang Liu, Haopeng Luan, Wenle Li   +27 more
wiley   +1 more source

An isocitrate lyase gene-deleted strain of <i>Nocardia seriolae</i> in live attenuated vaccine development against fish nocardiosis. [PDF]

Front Vet Sci
Lin G, Li Y, Hou S, Wen Y, Lei X, Huang T, Chen Y, Chen J, Xia L.   +8 more
europepmc   +1 more source

Who Will Protect the Children?

Annals of the Child Neurology Society, EarlyView.
William D. Graf, Leon G. Epstein
wiley   +1 more source

The evolutionary landscape and serotypic dynamics of avian infectious bronchitis virus from spike protein

iMetaOmics, EarlyView.
This study integrates two decades of surveillance with genomic and structural analyses to decipher how spike protein glycosylation haplotypes drive avian coronavirus evolution. We uncover how specific glycosylation patterns associate with receptor‐binding affinity, shape global transmission dynamics, and correlate with clinical outcomes.
Hao Zhang, Zongxi Han, Chuangchao Zou, Yihui Huang, Shiping Sun, Ouyang Peng, Usama Ashraf, Qiuping Xu, Yao Ge, Qixiang Kang, Xiuli Ma, Xinheng Zhang, Ye Zhao, Xin Yang, Hongning Wang, Guozhong Zhang, Qingmei Xie, Mang Shi, Yongsen Ruan, Min Liao, Shengwang Liu, Yongchang Cao   +21 more
wiley   +1 more source

Design and nonviral delivery of live attenuated vaccine to prevent chronic hepatitis C virus-like infection. [PDF]

Nat Commun
Trivedi S, Dravid P, Passchier TC, Murthy S, Kasudhan KS, Reguraman N, Kellar J, Chandra R, Cassady C, Burbelo PD, Grakoui A, Sharma H, Simmonds P, Kapoor A.   +13 more
europepmc   +1 more source

Immunogenicity of Live Attenuated B. pertussis BPZE1 Producing the Universal Influenza Vaccine Candidate M2e

, 2013
Hana Kammoun, X. Roux, Dominique Raze, Anne‐Sophie Debrie, Marina De Filette, Tine Ysenbaert, Nathalie Mielcarek, Xavier Saelens, Walter Fiers, Camille Locht   +9 more
openalex   +2 more sources

Comparison of 2 Different Regimens for Reactogenicity, Safety, and Immunogenicity of the Live Attenuated Oral Rotavirus Vaccine RIX4414 Coadministered with Oral Polio Vaccine in South African Infants [PDF]

, 2010
A. Duncan Steele, J. Reynders, F. Scholtz, P.K. Bos, M. C. de Beer, John Tumbo, C.F. van der Merwe, A. Delem, Béatrice De Vos   +8 more
openalex   +1 more source

Respiratory Syncytial Virus Under the Lens of Structure: From Prefusion Stabilization to Next‐Generation Immunotherapies

iNew Medicine, EarlyView.
This illustration integrates key concepts covered in the review, including high‐risk populations, viral structure, host entry factors, the replication cycle, and licensed antibody‐based prevention strategies. ABSTRACT Respiratory syncytial virus (RSV) is a negative‐sense RNA virus belonging to the genus Orthopneumovirus within the family Pneumoviridae.
Zekai Cheng, Qianqian Wang, Jiachen Zhang, Sandra Chiu   +3 more
wiley   +1 more source

CocoVax: a web server for codon-based deoptimization of viral genes in live attenuated vaccine design. [PDF]

Nucleic Acids Res
Li J, Shuai S.
europepmc   +1 more source

Epigenetic inflammatory memory and periodontal disease: Mechanisms and clinical significance for comorbidities

Journal of Periodontology, EarlyView.
Abstract Historically, immunological memory was considered an exclusive feature of adaptive immunity. However, innate immune cells have recently been shown to record and maintain epigenetically imprinted memory of earlier infectious or inflammatory challenges.
George Hajishengallis
wiley   +1 more source