Results 11 to 20 of about 461,407 (167)

Possible alignment of the EU BSE surveillance with the new WOAH provisions. [PDF]

EFSA J
Abstract The European Commission requested the assessment of the capacity of the surveillance provisions of the World Organization for Animal Health (WOAH) to detect bovine spongiform encephalopathy (BSE) cases (C‐, H‐ and L‐type) in the European Union (EU) and to propose if any current EU surveillance provisions should be kept.
EFSA Panel on Animal Health and Welfare (AHAW), Nielsen SS, Alvarez J, Boklund A, Dippel S, Dórea F, Figuerola J, Herskin MS, Michel V, Miranda Chueca MA, Nannoni E, Riber AB, Stahl K, Stegeman JA, Thulke HH, Tuyttens F, Winckler C, Arnold M, Ducrot C, Griffin J, Ru G, Simmons M, Ashe S, Pelaez AO, Kryemadhi K, Nonno R.   +25 more
europepmc   +2 more sources

A quantitative assessment of the amount of prion diverted to category 1 materials and wastewater during processing [PDF]

, 2013
In this article the development and parameterization of a quantitative assessment is described that estimates the amount of TSE infectivity that is present in a whole animal carcass (bovine spongiform encephalopathy [BSE] for cattle and classical ...
Adkin, A., Kelly, Louise, Donaldson, Neil   +2 more
core   +4 more sources

Animal prion diseases: A review of intraspecies transmission [PDF]

Open Veterinary Journal, 2021
Animal prion diseases are a group of neurodegenerative, transmissible, and fatal disorders that affect several animal species. The causative agent, prion, is a misfolded isoform of normal cellular prion protein, which is found in cells with higher ...
Mauro Julián Gallardo, Fernando Oscar Delgado   +1 more
doaj   +1 more source

The European Union summary report on surveillance for the presence of transmissible spongiform encephalopathies (TSE) in 2024. [PDF]

EFSA J
ABSTRACT This report presents results of surveillance on transmissible spongiform encephalopathies in bovines, sheep, goats, cervids and other species, and genotyping in sheep and goats, carried out in 2024 by 27 EU Member States (EU27, MS), the UK (in respect of Northern Ireland, (XI)) and 8 non‐EU reporting countries: Bosnia and Herzegovina, Iceland,
European Food Safety Authority (EFSA), Nonno R, Ru G, Aminalragia-Giamini R, Iancu C, Ortiz-Pelaez A, Kryemadhi K, Baldinelli F.   +7 more
europepmc   +2 more sources

RT-QuIC detection of pathological prion protein in subclinical goats following experimental oral transmission of L-type BSE

BMC Research Notes, 2021
Objective The spread of bovine spongiform encephalopathy (BSE) agent to small ruminants is still a major issue in the surveillance of transmissible spongiform encephalopathies (TSEs). L-type bovine spongiform encephalopathy (L-BSE) is an atypical form of
Alessandra Favole, Maria Mazza, Antonio D’Angelo, Guerino Lombardi, Claudia Palmitessa, Luana Dell’Atti, Giulia Cagnotti, Elena Berrone, Marina Gallo, Tiziana Avanzato, Erika Messana, Loretta Masoero, Pier Luigi Acutis, Daniela Meloni, Franco Cardone, Maria Caramelli, Cristina Casalone, Cristiano Corona   +17 more
doaj   +1 more source

Intraspecies transmission of BASE induces clinical dullness and amyotrophic changes. [PDF]

PLoS Pathogens, 2008
The disease phenotype of bovine spongiform encephalopathy (BSE) and the molecular/ biological properties of its prion strain, including the host range and the characteristics of BSE-related disorders, have been extensively studied since its discovery in ...
Guerino Lombardi, Cristina Casalone, Antonio D' Angelo, Daniela Gelmetti, Gloria Torcoli, Ilaria Barbieri, Cristiano Corona, Elisa Fasoli, Alessia Farinazzo, Michele Fiorini, Matteo Gelati, Barbara Iulini, Fabrizio Tagliavini, Sergio Ferrari, Maria Caramelli, Salvatore Monaco, Lorenzo Capucci, Gianluigi Zanusso   +17 more
doaj   +1 more source

Detection of classical BSE prions in asymptomatic cows after inoculation with atypical/Nor98 scrapie

Veterinary Research, 2023
The emergence of bovine spongiform encephalopathy (BSE) prions from atypical scrapie has been recently observed upon experimental transmission to rodent and swine models. This study aimed to assess whether the inoculation of atypical scrapie could induce
Marina Betancor, Belén Marín, Alicia Otero, Carlos Hedman, Antonio Romero, Tomás Barrio, Eloisa Sevilla, Jean-Yves Douet, Alvina Huor, Juan José Badiola, Olivier Andréoletti, Rosa Bolea   +11 more
doaj   +1 more source

Molecular characterisation of atypical BSE prions by mass spectrometry and changes following transmission to sheep and transgenic mouse models. [PDF]

PLoS ONE, 2018
The prion hypothesis proposes a causal relationship between the misfolded prion protein (PrPSc) molecular entity and the disease transmissible spongiform encephalopathy (TSE). Variations in the conformation of PrPSc are associated with different forms of
Adriana Gielbert, Jemma K Thorne, Jane M Plater, Leigh Thorne, Peter C Griffiths, Marion M Simmons, Claire A Cassar   +6 more
doaj   +1 more source

Experimental transmission of ovine atypical scrapie to cattle

Veterinary Research, 2023
Classical bovine spongiform encephalopathy (BSE) in cattle was caused by the recycling and feeding of meat and bone meal contaminated with a transmissible spongiform encephalopathy (TSE) agent but its origin remains unknown. This study aimed to determine
Timm Konold, John Spiropoulos, Janet Hills, Hasina Abdul, Saira Cawthraw, Laura Phelan, Amy McKenna, Lauren Read, Sara Canoyra, Alba Marín-Moreno, Juan María Torres   +10 more
doaj   +1 more source

Oral Transmission of L-type Bovine Spongiform Encephalopathy in Primate Model

Emerging Infectious Diseases, 2012
We report transmission of atypical L-type bovine spongiform encephalopathy to mouse lemurs after oral or intracerebral inoculation with infected bovine brain tissue.
Nadine Mestre-Francés, Simon Nicot, Sylvie Rouland, Anne-Gaëlle Biacabe, Isabelle Quadrio, Armand Perret-Liaudet, Thierry Baron, Jean-Michel Verdier   +7 more
doaj   +1 more source