Results 21 to 30 of about 461,407 (167)

Use of bovine recombinant prion protein and real-time quaking-induced conversion to detect cattle transmissible mink encephalopathy prions and discriminate classical and atypical L- and H-Type bovine spongiform encephalopathy. [PDF]

PLoS ONE, 2017
Prions are amyloid-forming proteins that cause transmissible spongiform encephalopathies through a process involving conversion from the normal cellular prion protein to the pathogenic misfolded conformation (PrPSc).
Soyoun Hwang, Justin J Greenlee, Eric M Nicholson   +2 more
doaj   +1 more source

Differentiation of ruminant transmissible spongiform encephalopathy isolate types, including bovine spongiform encephalopathy and CH1641 scrapie [PDF]

, 2010
With increased awareness of the diversity of transmissible spongiform encephalopathy (TSE) strains in the ruminant population, comes an appreciation of the need for improved methods of differential diagnosis. Exposure to bovine spongiform encephalopathy (
Bossers, A., A. Bossers, Y. Tang, Sauer, M., M. Sauer, L. J. M. van Keulen, J. P. M. Langeveld, J. G. Jacobs, Keulen, L.J.M., van, van Keulen, L.J.M., Tang, Y., Jacobs, J.G., Langeveld, J.P.M.   +12 more
core   +1 more source

An overview of animal prion diseases

Virology Journal, 2011
Prion diseases are transmissible neurodegenerative conditions affecting human and a wide range of animal species. The pathogenesis of prion diseases is associated with the accumulation of aggregates of misfolded conformers of host-encoded cellular prion ...
Imran Muhammad, Mahmood Saqib
doaj   +1 more source

Classical BSE prions emerge from asymptomatic pigs challenged with atypical/Nor98 scrapie

Scientific Reports, 2021
Pigs are susceptible to infection with the classical bovine spongiform encephalopathy (C-BSE) agent following experimental inoculation, and PrPSc accumulation was detected in porcine tissues after the inoculation of certain scrapie and chronic wasting ...
Belén Marín, Alicia Otero, Séverine Lugan, Juan Carlos Espinosa, Alba Marín-Moreno, Enric Vidal, Carlos Hedman, Antonio Romero, Martí Pumarola, Juan J. Badiola, Juan María Torres, Olivier Andréoletti, Rosa Bolea   +12 more
doaj   +1 more source

Bovine PrP expression levels in transgenic mice influence transmission characteristics of atypical bovine spongiform encephalopathy. [PDF]

J Gen Virol, 2012
Until recently, transmissible spongiform encephalopathy (TSE) disease in cattle was thought to be caused by a single agent strain, bovine spongiform encephalopathy (BSE) (classical BSE or BSE-C).
Wilson R, Hart P, Piccardo P, Hunter N, Casalone C, Baron T, Barron RM.   +6 more
europepmc   +2 more sources

No H- and L-type cases in Belgium in cattle diagnosed with bovine spongiform encephalopathy (1999-2008) aging seven years and older [PDF]

, 2010
Background The bovine spongiform encephalopathy (BSE) epidemic presented homogeneity of the phenotype. This classical BSE (called C-type) was probably due to the contamination of the food chain by a single prion strain.
van Keulen Lucien, Rodeghiero Caroline, Caroline Rodeghiero, S. Durand, Dobly Alexandre, Alexandre Dobly, Roels, S., Emmanuel Vanopdenbosch, A. Dobly, Sloovere, J., de, Jessica De Sloovere, Patrick Van Muylem, van Muylem, P., Van Muylem Patrick, Langeveld Jan, Keulen, L.J.M., van, van Keulen, L.J.M., Stefan Roels, Vanopdenbosch, E., J. De Sloovere, Dobly, A., Langeveld, J.P.M., Geeroms Riet, Vanopdenbosch Emmanuel, Lucien van Keulen, P. Van Muylem, Muylem, P., van, Jan Langeveld, de Sloovere, J., Rodeghiero, C., Stéphanie Durand, Roels Stefan, Durand Stéphanie, De Sloovere Jessica, L. van Keulen, Geeroms, R., C. Rodeghiero, R. Geeroms, Durand, S.V.M., J. Langeveld, S. Roels, E. Vanopdenbosch, Riet Geeroms   +42 more
core   +1 more source

Atypical status of bovine spongiform encephalopathy in Poland: a molecular typing study [PDF]

, 2008
The aim of this study was to analyze molecular features of protease-resistant prion protein (PrPres) in Western blots of BSE cases diagnosed in Poland with respect to a possible atypical status.
Polak, M.P., Zmudzinski, J.F., Jacobs, J.G., Langeveld, J.P.M.   +3 more
core   +1 more source

B‐cell leukemia in an adult sheep

Veterinary Clinical Pathology, Volume 52, Issue 4, Page 716-721, December 2023., 2023
Abstract B‐cell leukemia is a rare form of hematologic neoplasia in sheep, especially in adult animals. We present a case report of a 5‐year‐old WhiteFace Sheep wether with suspected acute lymphoblastic leukemia. The patient, a second‐generation relative of ewes experimentally inoculated with atypical scrapie, exhibited acute lethargy and loss of ...
Adriana P. Furtado, Lindsay M. Fry, Lindsay M. W. Piel, Reginaldo G. Bastos, David A. Schneider, Mara S. Varvil   +5 more
wiley   +1 more source

Studies of the transmissibility of the agent of bovine spongiform encephalopathy to the domestic chicken [PDF]

, 2011
Background: Transmission of the prion disease bovine spongiform encephalopathy (BSE) occurred accidentally to cattle and several other mammalian species via feed supplemented with meat and bone meal contaminated with infected bovine tissue.
Stack Michael J, Robert B Green, Paul R Webb, Simmons, M.M., Timm Konold, Spencer, Y.I., Moore Jo, Marion M Simmons, Ian Dexter, Moore, J., Michael Dawson, Jo Moore, Chaplin, M.J., Webb, P.R., Dexter, I., Wells Gerald AH, Austin, A.R., Dawson, M., Austin Anthony R, Gerald AH Wells, Michael J Stack, Anthony R Austin, Wells, G.A.H, Green Robert B, Langeveld, J.P.M., Ian W Blamire, Stack, M.J., Melanie J Chaplin, Simmons, M., Konold Timm, Dawson Michael, Spencer Yvonne I, Hawkins, S.A.C., Konold, T., Simmons Marion M, Chaplin Melanie J, Hawkins Stephen AC, Dexter Ian, Blamire Ian W, Langeveld Jan PM, Jan PM Langeveld, Webb, P.R.I., Yvonne I Spencer, Green, R.B., Blamire, I.W., Webb Paul R, Stephen AC Hawkins   +46 more
core   +1 more source

The European Union summary report on surveillance for the presence of transmissible spongiform encephalopathies (TSE) in 2022

EFSA Journal, Volume 21, Issue 11, November 2023., 2023
Abstract This report presents the results of surveillance on transmissible spongiform encephalopathies (TSE) in cattle, sheep, goats, cervids and other species, and genotyping in sheep and goats, carried out in 2022 by 27 Member States (MS, EU27), the United Kingdom (in respect of Northern Ireland [XI]) and other eight non‐EU reporting countries ...
European Food Safety Authority (EFSA)
wiley   +1 more source