Temporal Dynamics of Viremia in Hemorrhagic Fever With Renal Syndrome Patients
ABSTRACT The pathogenesis of hemorrhagic fever with renal syndrome (HFRS) remains incompletely understood. Currently, the clinical diagnosis of HFRS primarily relies on epidemiological history and clinical presentation, while the confirmation of HFRS depends mainly on the detection of hemorrhagic fever antibodies.
ShuWei Ma +6 more
wiley +1 more source
Abstract A 6‐year‐old, spayed, female labrador retriever was presented with left distal radial swelling. Imaging, cytology and biopsy identified an aggressive radial lesion with metastasis to the left axillary lymph node, and a diagnosis of presumptive osteosarcoma was made.
Veronica Perez‐Rodriguez +4 more
wiley +1 more source
Opioids in breast cancer: Between analgesia and modulation of tumour progression
Preclinical investigations consistently demonstrate that activation of μ‐opioid receptors and δ‐opioid receptors promote proliferation, migration, angiogenesis, epithelial‐mesenchymal transition, acquisition of cancer stem cell phenotypes, and chemoresistance.
Marianna Ciwun +2 more
wiley +1 more source
Editorial: Atypical Functions of Leukocyte Chemoattractant Receptors
José Luis Rodríguez-Fernández +3 more
doaj +1 more source
Targeting Inflammation and Immune Regulation in Chronic Inflammation Associated Cancers
Chronic inflammation sustains activation of key inflammatory pathways, including Nuclear factor kappa B (NF‐κB), Interleukin‐6‐signal transducer and activator of transcription 3 (IL6‐STAT3), Phosphoinositide 3‐kinase/Akt (PI3K/Akt), and Wingless/β‐catenin (Wnt/β‐catenin) signaling. This promotes immune dysregulation through the expansion and functional
Lawan Rabiu +5 more
wiley +1 more source
Synthetic and Endogenous Cannabinoids Inhibit Breast Cancer Cell Growth and Metastasis [PDF]
With one million cases diagnosed yearly worldwide, breast cancer is the second most common cancer in women. Metastasis to the brain is the leading cause of death in breast cancer patients due to the inability of drug treatments to cross the blood brain ...
Smith, Diane
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Neuroinflammation as a result of non‐neurotropic herpesvirus infection
Atypical memory B cells (ABCs) might stimulate autoreactive T cells to cause neuroinflammation and CNS myeloid cell activation during MS. Abstract The non‐neurotropic Epstein Barr virus (EBV) has been suggested to initiate the prodromal phase of multiple sclerosis (MS), often years before the first clinical symptoms. This review discusses mechanisms by
Christian Münz
wiley +1 more source
B Cell Subsets and Atherosclerosis: Updates and Emerging Concepts
ABSTRACT Atherosclerotic cardiovascular disease (ASCVD) is increasingly recognized not just as a lipid‐driven disease, but as a complex interplay between vascular cells and the immune system. Accumulating evidence highlights a central, yet heterogeneous role for B cells in atherogenesis, with distinct subsets displaying opposing roles.
Sophieke Lems +3 more
wiley +1 more source
Integrating Flow Cytometry in the Diagnostic Work of HIV‐Associated Hodgkin's Lymphomas
ABSTRACT Hodgkin lymphoma (HL) is prevalent worldwide and typically presents symptoms like sudden pain, swelling, and weight loss. Classical HL (cHL) is largely treatable with modern risk‐adapted and response‐based therapy. cHL represents one of the most common malignancies occurring during the course of evolution in patients living with HIV.
Maria Santa +23 more
wiley +1 more source
DARC shuttles inflammatory chemokines across the blood-brain barrier during autoimmune central nervous system inflammation [PDF]
Trafficking of T cells into the CNS is a pathophysiological hallmark of multiple sclerosis. Using an invitro model of the blood-brain barrier, Minten etal.
Alt, Carsten +8 more
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