Results 141 to 150 of about 112,681 (232)
The role of neutrophils in the pathophysiology of inflammatory bowel diseases
Abstract Objectives Inflammatory bowel disease (IBD) encompasses a spectrum of chronic disorders of the gastrointestinal tract, with a potential bidirectional relationship with periodontitis. Neutrophils are key regulators of immune‐inflammatory responses and play a major role in both diseases.
Joao Paulo Steffens +8 more
wiley +1 more source
CXCR4 and its ligand CXCL12 mediate the homing of progenitor cells in the bone marrow and their recruitment to sites of injury, as well as affect processes such as cell arrest, survival and angiogenesis.
Lukas ePawig +4 more
doaj +1 more source
The Silent Link: Exploring the Impact of Periodontal Diseases on Head and Neck Carcinogenesis
ABSTRACT Objectives Oral dysbiosis can accelerate the progression of head and neck squamous cell carcinoma (HNSCC) by fostering a pro‐inflammatory, immunosuppressive, and metabolically altered environment. This narrative review examines the relationships between periodontitis‐associated bacteria and HNSCC, focusing on their impact on oncogenic pathways,
Yashmin Afshar, Nima Rezaei
wiley +1 more source
Chemokine receptors CCR5 and CXCR4 are considered the main coreceptors for initial HIV infection, replication and transmission, and subsequent AIDS progression.
Thomas D'huys +3 more
doaj +1 more source
The role of lymphatics in renal inflammation [PDF]
Progressive renal diseases are characterized by tubulointerstitial inflammatory cell recruitment, tubular atrophy and fibrosis. Various aspects of the recruitment of leukocytes have been extensively studied, but the exit routes (i.e.
Bonani, Marco +2 more
core
GRKs and arrestins: Nomenclature and functions in GPCR‐dependent and ‐independent signalling
G protein‐coupled receptor (GPCR) kinases (GRKs) and arrestins play a critical role in the regulation of GPCR signalling. Historic names of mammalian GRKs were replaced by systematic ones in the 1990s; however, both kinds of names are currently in use for mammalian arrestins.
Vsevolod V. Gurevich
wiley +1 more source
The Role of the CXCL12/CXCR4/ACKR3 Axis in Autoimmune Diseases
Chemokine receptors are members of the G protein-coupled receptor superfamily. These receptors are intimately involved in cell movement, and thus play a critical role in several physiological and pathological situations that require the precise ...
Eva M. García-Cuesta +5 more
doaj +1 more source
Impaired neutrophil directional chemotactic accuracy in chronic periodontitis patients [PDF]
Aim: To investigate the chemotactic accuracy of peripheral blood neutrophils from patients with chronic periodontitis compared with matched healthy controls, before and after non-surgical periodontal therapy.
Agarwal +72 more
core +2 more sources
Congenital aleukemic leukemia cutis mimicking infantile hemangioma
JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Ana Clara Maia Palhano +5 more
wiley +1 more source
Immune endotypes in tuberculosis: Keys to decoding disease complexity
Abstract Tuberculosis (TB) remains a major global health challenge, with multi‐drug antibiotic regimens as the current standard of care. While effective at killing Mycobacterium tuberculosis, these treatments do not resolve persistent inflammation, prevent lung damage, or reverse immune dysregulation that contribute to poor outcomes and disease ...
Shamila D. Alipoor +4 more
wiley +1 more source

