Results 161 to 170 of about 28,527 (253)

Investigating the interaction of ACKR1 and c-Myc in the breast carcinoma tumor microenvironment modulation

Discover Oncology
This study investigates the interplay between the Atypical chemokine receptors (ACKR1)/Decoy receptor for chemokines (DARC) and key molecular markers, including CCL8, c-MYC, ALDH1, and CHEK2, in breast cancer.
Joyeeta Talukdar, Arnab Nayek, Gayatri Gogoi, Tryambak P. Srivastava, Isha Goel, Om Saswat Sahoo, Ruby Dhar, Subhradip Karmakar   +7 more
doaj   +1 more source

Murine bone marrow macrophages and human monocytes do not express atypical chemokine receptor 1

, 2022
Antal Rot, Julia Gutjahr, Aindrila Biswas, Maria Aslani, Elin Hub, Aude Thiriot, Ulrich H. von Andrian, Remco T. A. Megens, Christian Weber, Johan Duchêne   +9 more
openalex   +2 more sources

Receptor‐Dependent and ‐Independent Effects of Hemin on Platelet Plasma Membrane Disintegration

The FASEB Journal, Volume 40, Issue 2, 31 January 2026.
Microhemorrhages lead to the release of erythrocytes, which are then degraded and lysed. These hemolyses result in the liberation of free iron‐containing hemin. Hemin induces platelet activation and ferroptosis. Inhibition of GPVI/CLEC‐2 receptor‐mediated ITAM‐signaling inhibits hemin‐induced platelet activation (low hemin concentrations). Deferoxamine,
Zoi Laspa, Anne‐Katrin Rohlfing, Ravi Hochuli, Pamela Weronika Sowa, Tatsiana Castor, Meinrad Paul Gawaz   +5 more
wiley   +1 more source

Down regulation of estrogen receptors (ER; ER) and atypical chemokine receptors (ACKR 2; ACKR3; ACKR4) to increase 17β-estradiol (E2) levels in MCF-7 in-vitro study

Basic & Clinical Cancer Research
Background: Oestrogen plays a vital role in breast development and is strongly related to breast cancer. This research article delves into this paradox.
Shruti Talashi
doaj  

Deletion of atypical chemokine receptor 3 (ACKR3) increases immune cells at the fetal-maternal interface

, 2020
Kelsey E. Quinn, Brooke C. Matson, Kathleen M. Caron   +2 more
openalex   +2 more sources

Tails of the unexpected – an atypical receptor for the chemokine RANTES/CCL5 expressed in brain [PDF]

, 2006
James E. Pease
openalex   +1 more source

Развитие иммунного ответа при пневмонии, вызванной Klebsiella pneumoniae. Часть 3 [PDF]

, 2017
В статье на основании литературных данных освещена роль хемокинов и дефензинов в развитии иммунного ответа при пневмонии, вызванной Klebsiella pneumoniae.
Абатуров, А.Е., Никулина, А.А.   +1 more
core  

Cancer-associated epithelial cell adhesion molecule (EpCAM; CD326) enables epidermal Langerhans cell motility and migration in vivo

, 2012
After activation, Langerhans cells (LC), a distinct subpopulation of epidermis-resident dendritic cells, migrate from skin to lymph nodes where they regulate the magnitude and quality of immune responses initiated by epicutaneously applied antigens ...
Feng, X., Gaiser, M., Germain, R., Igyarto, B., Kaplan, D., Lämmermann, T., Tessarollo, L., Udey, a.   +7 more
core   +1 more source

Structural basis for selectivity and antagonism in extracellular GPCR-nanobodies

Nature Communications
G protein-coupled receptors (GPCRs) are pivotal therapeutic targets, but their complex structure poses challenges for effective drug design. Nanobodies, or single-domain antibodies, have emerged as a promising therapeutic strategy to target GPCRs ...
Roman R. Schlimgen, Francis C. Peterson, Raimond Heukers, Martine J. Smit, John D. McCorvy, Brian F. Volkman   +5 more
doaj   +1 more source

Physiol Rep [PDF]

Inhalation of ozone (O|), a gaseous air pollutant, causes lung injury, lung inflammation, and airway hyperresponsiveness. Macrophages, mast cells, and neutrophils contribute to one or more of these sequelae induced by O|Furthermore, each of these ...

core