Results 161 to 170 of about 27,026 (263)

Down regulation of estrogen receptors (ER; ER) and atypical chemokine receptors (ACKR 2; ACKR3; ACKR4) to increase 17β-estradiol (E2) levels in MCF-7 in-vitro study

Basic & Clinical Cancer Research
Background: Oestrogen plays a vital role in breast development and is strongly related to breast cancer. This research article delves into this paradox.
Shruti Talashi
doaj  

Investigating the interaction of ACKR1 and c-Myc in the breast carcinoma tumor microenvironment modulation

Discover Oncology
This study investigates the interplay between the Atypical chemokine receptors (ACKR1)/Decoy receptor for chemokines (DARC) and key molecular markers, including CCL8, c-MYC, ALDH1, and CHEK2, in breast cancer.
Joyeeta Talukdar, Arnab Nayek, Gayatri Gogoi, Tryambak P. Srivastava, Isha Goel, Om Saswat Sahoo, Ruby Dhar, Subhradip Karmakar   +7 more
doaj   +1 more source

Reactivity of human and porcine natural interferon-alpha producing cells to immunostimulatory DNA [PDF]

, 2003
The interferon-α (IFN-α) inducing capacity of various forms of immunostimulatory DNA and the identity of the IFN-α producing cells (IPC) were studied in human and porcine leukocytes.
Magnusson, Mattias
core  

In Silico Studies on DARC. [PDF]

, 2009
International audienceThe Duffy Antigen/Receptor for Chemokine (DARC) is a seven segment transmembrane protein. It was firstly discovered as a blood group antigen and was the first specific gene locus assigned to a specific autosome in man.
Autin, Ludovic, Bertrand, Olivier, Colin, Yves, De Brevern, Alexandre, Etchebest, Catherine   +4 more
core   +2 more sources

Tails of the unexpected – an atypical receptor for the chemokine RANTES/CCL5 expressed in brain [PDF]

, 2006
James E. Pease
openalex   +1 more source

Murine bone marrow macrophages and human monocytes do not express atypical chemokine receptor 1

, 2022
Antal Rot, Julia Gutjahr, Aindrila Biswas, Maria Aslani, Elin Hub, Aude Thiriot, Ulrich H. von Andrian, Remco T. A. Megens, Christian Weber, Johan Duchêne   +9 more
openalex   +2 more sources

Phenotypic evolution of circulating plasma cells from early precursor stages to multiple myeloma

Haematologica
Circulating tumour plasma-cells (CTPCs) have emerged as valuable diagnostic and prognostic marker in multiple myeloma (MM), with their presence linked to progression from precursor stages and poorer outcomes in newly diagnosed MM (NDMM).
Martin Pietzsch, Sina Alexandra Beer, Lucca Marco Kimmich, Chiara Windsor, Sarah Gekeler, Britta Besemer, Anna Maria Paczulla Stanger   +6 more
doaj   +1 more source

Deletion of atypical chemokine receptor 3 (ACKR3) increases immune cells at the fetal-maternal interface

, 2020
Kelsey E. Quinn, Brooke C. Matson, Kathleen M. Caron   +2 more
openalex   +2 more sources

Structural basis for selectivity and antagonism in extracellular GPCR-nanobodies

Nature Communications
G protein-coupled receptors (GPCRs) are pivotal therapeutic targets, but their complex structure poses challenges for effective drug design. Nanobodies, or single-domain antibodies, have emerged as a promising therapeutic strategy to target GPCRs ...
Roman R. Schlimgen, Francis C. Peterson, Raimond Heukers, Martine J. Smit, John D. McCorvy, Brian F. Volkman   +5 more
doaj   +1 more source

Pharmacological characterization and radiolabeling of VUF15485, a high-affinity small-molecule agonist for the atypical chemokine receptor ACKR3 [PDF]

, 2023
Aurélien Zarca, Ilze Adlere, Cristina Perpiñá-Viciano, Marta Arimont, Max Meyrath, Ícaro A. Simon, Jan Paul Bebelman, D.J. van der Laan, Hans Custers, Elwin Janssen, Kobus L. Versteegh, Reggie Bosma, Iwan J. P. de Esch, Henry F. Vischer, Maikel Wijtmans, Martyna Szpakowska, Andy Chevigné, Carsten Hoffmann, Chris de Graaf, Barbara Zarzycka, Albert D. Windhorst, Martine J. Smit, Rob Leurs   +22 more
openalex   +1 more source