Results 231 to 240 of about 28,527 (253)
Some of the next articles are maybe not open access.

Related searches:

Chemokine sequestration by atypical chemokine receptors

Biochemical Society Transactions, 2006
Leucocyte migration is essential for robust immune and inflammatory responses, and plays a critical role in many human diseases. Chemokines, a family of small secreted protein chemoattractants, are of fundamental importance in this process, directing leucocyte trafficking by signalling through heptahelical G-protein-coupled receptors expressed by the ...
C A H, Hansell   +2 more
openaire   +2 more sources

New nomenclature for atypical chemokine receptors

Nature Immunology, 2014
Chemokine receptors, the largest family of receptors containing a seven-transmembrane domain that are expressed on leukocytes, can be categorized into two principal subgroups that are highly related phylogenetically and cluster in the same branch of class A rhodopsin-like receptors: a larger subgroup (eighteen in humans) of G protein– coupled leukocyte
Bachelerie Françoise   +9 more
openaire   +4 more sources

Immune regulation by atypical chemokine receptors

Nature Reviews Immunology, 2013
Chemokines have fundamental roles in regulating immune and inflammatory responses, primarily through their control of leukocyte migration and localization. The biological functions of chemokines are typically mediated by signalling through G protein-coupled chemokine receptors, but chemokines are also bound by a small family of atypical chemokine ...
Robert J B, Nibbs, Gerard J, Graham
openaire   +2 more sources

Atypical Chemokine Receptors in Inflammatory Disease

Current Molecular Medicine, 2009
There is considerable interest in the therapeutic utility of inhibiting cellular trafficking in a variety of inflammatory diseases. Approaches including inhibition of adhesion molecule function and in particular of chemokine effector function have met with high levels of success in many models of disease but have been of less value in application to ...
Manish, Patel   +2 more
openaire   +2 more sources

Canonical and atypical chemokine receptors in the neutrophil life cycle

Cytokine, 2023
Chemokines are mainly studied for their local function in the control of leukocyte extravasation in homeostatic and inflammatory conditions. However, they have additional roles at the systemic level including the regulation of the hematopoietic process and leukocyte differentiation.
Rachele Di Donato   +2 more
openaire   +2 more sources

Atypical chemokine receptors—“chemokine PACMANs” as new therapeutic targets in glomerulonephritis

Kidney International, 2018
Inflammatory cells are recruited to sites of inflammation by chemokines. Atypical chemokine receptors regulate chemokine gradients, thereby limiting inflammation. In this issue of Kidney International, atypical chemokine receptor 2 knockouts were described to be increasingly susceptible to immune complex-mediated glomerulonephritis.
Kathrin, Eller, Alexander R, Rosenkranz
openaire   +2 more sources

Home - About - Disclaimer - Privacy