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Chemokine sequestration by atypical chemokine receptors
Biochemical Society Transactions, 2006Leucocyte migration is essential for robust immune and inflammatory responses, and plays a critical role in many human diseases. Chemokines, a family of small secreted protein chemoattractants, are of fundamental importance in this process, directing leucocyte trafficking by signalling through heptahelical G-protein-coupled receptors expressed by the ...
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New nomenclature for atypical chemokine receptors
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Nature Reviews Immunology, 2013Chemokines have fundamental roles in regulating immune and inflammatory responses, primarily through their control of leukocyte migration and localization. The biological functions of chemokines are typically mediated by signalling through G protein-coupled chemokine receptors, but chemokines are also bound by a small family of atypical chemokine ...
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Atypical Chemokine Receptors in Inflammatory Disease
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