Results 81 to 90 of about 25,762 (279)

Rational use of eculizumab in secondary atypical hemolytic uremic syndrome

Frontiers in Immunology
Background Secondary atypical hemolytic uremic syndrome (secondary aHUS) is a heterogeneous group of thrombotic microangiopathies (TMA) associated with various underlying conditions. Unlike primary aHUS, there is still no hard evidence on the efficacy of
Lucía Cordero, T. Cavero, Eduardo Gutiérrez, Hernando Trujillo, J. Sandino, P. Auñón, Marta Rivero, Enrique Morales   +7 more
semanticscholar   +1 more source

Atypical Hemolytic Uremic Syndrome after SARS-CoV-2 Infection: Report of Two Cases

International Journal of Environmental Research and Public Health, 2022
Atypical hemolytic uremic syndrome (aHUS) is a life-threatening disease causing systemic thrombotic microangiopathy (TMA) due to the fact of complement dysregulation.
Iwona Smarz-Widelska, Małgorzata Syroka-Główka, Joanna Janowska-Jaremek, M. Koziol, W. Załuska   +4 more
semanticscholar   +1 more source

Common Hematologic Emergencies—Acute Promyelocytic Leukemia and Microangiopathic Hemolytic Anemias—A Pivotal Role of Clinical Laboratory

International Journal of Laboratory Hematology, EarlyView.
ABSTRACT Hematologic emergencies are urgent health conditions which result in significant mortality and morbidity unless timely therapeutic measures are taken. Therapeutic success depends on their timely and accurate recognition by hematology laboratory services.
Ganna Shestakova, Nicolas Ulrich Edgar, Anton V. Rets   +2 more
wiley   +1 more source

Eculizumab experience in an adult patient with atypical hemolytic uremic syndrome

Saudi Journal of Kidney Diseases and Transplantation, 2017
Atypical hemolytic-uremic syndrome is a disease characterized by nonimmune hemolytic anemia, thrombocytopenia, and renal failure. In this study, we present a case of a patient with atypical hemolytic-uremic syndrome treated successfully with eculizumab ...
Funda Sari, Ayça Inci, Volkan Karakus, Banu Yilmaz, Metin Sarikaya, Refik Olmaz, Erdal Kurtoglu   +6 more
doaj   +1 more source

Concurrent Scrub Typhus, Dengue, and Leptospirosis: A Rare Triple Co‐Infection: A Case Report and Comprehensive Literature Review

Clinical Case Reports, Volume 14, Issue 2, February 2026.
ABSTRACT In endemic areas, acute undifferentiated febrile illness has a wide differential with overlapping features that can lead to misdiagnosis. Although triple co‐infection with scrub typhus, dengue, and leptospirosis is extremely rare, high clinical suspicion and early detection are vital to avoid delayed treatment, multi‐organ dysfunction, and ...
Sulav Kumar Jha, Bistrit Dahal, Anamika Adhikari, Kushal Singh Basnet, Shivaditya Singh, Manaswi Acharya   +5 more
wiley   +1 more source

Anti factor H autoantibodies block C-terminal recognition function of factor H in hemolytic uremic syndrome [PDF]

, 2007
The atypical form of the kidney disease hemolytic uremic syndrome (aHUS) is associated with defective complement regulation. In addition to mutations in complement regulators, factor H (FH)-specific autoantibodies have been reported for aHUS patients ...
Dahse, H. M., Hoyer, P. F., Józsi, Mihály, Liu, W. S., Strobel, S.   +4 more
core   +1 more source

Modulators of Diacylglycerol Kinase Activity: A Review of Advances and Challenges

Medicinal Research Reviews, Volume 46, Issue 1, Page 149-175, January 2026.
ABSTRACT Catalyzing the conversion of diacylglycerol (DAG) in phosphatidic acid (PA), diacylglycerol kinases (DGKs) play a pivotal role in all the physiological processes modulated by these two bioactive lipids, such as lipid metabolism and immune regulation.
Luisa Racca, Gianluca Baldanzi, Alberto Massarotti   +2 more
wiley   +1 more source

Eculizumab for Gemcitabine-Induced Hemolytic Uremic Syndrome: A Novel Therapy for an Emerging Condition [PDF]

, 2015
Introduction Atypical hemolytic uremic syndrome (aHUS), a thrombotic microangiopathy (TMA), is a disease characterized by hemolytic anemia, thrombocytopenia, and renal impairment. Gemcitabine, a commonly used chemotherapy, is emerging as a cause of aHUS.
Karkowsky, MD, Raphael, Parikh, MD, Kinjal   +1 more
core   +2 more sources

Pathogenesis of Atypical Hemolytic Uremic Syndrome

Journal of Atherosclerosis and Thrombosis, 2019
Atypical hemolytic uremic syndrome (aHUS) is a type of thrombotic microangiopathy (TMA) defined by thrombocytopenia, microangiopathic hemolytic anemia, and renal failure. aHUS is caused by uncontrolled complement activation in the alternative pathway (AP).
Yoshida, Yoko, Kato, Hideki, Ikeda, Yoichiro, Nangaku, Masaomi   +3 more
openaire   +3 more sources

Molecular Characterization of Virulent Genes and Antimicrobial Resistance Patterns of Escherichia coli Isolated From Calf Scours in Western Iran

Veterinary Medicine and Science, Volume 12, Issue 1, January 2026.
This study in Western Iran analysed E. coli in diarrhoeic neonatal calves and identified 307 isolates from 350 faecal samples. The pathotypes included EHEC (36.59%), EPEC (20.42%), ETEC (14.46%), STEC (12.34%) and NTEC (11.48%), with four STEC O157:H7 isolates. Serotypes O103 and O15 were the most common.
Elham Ahmadi, Mohammad Sadegh Safaee Firouzabadi, Seyed Ali Mousavi Rad, Samira Ghorbani   +3 more
wiley   +1 more source