Results 131 to 140 of about 24,341 (292)
Вестник анестезиологии и реаниматологии, 2018 The article describes the follow-up over the development of atypical hemolytic-uremic syndrome in the female patient suffering menometrorrhagia which manifested with concurrent metrorrhagia and was accompanied with acute renal failure.
A. V. Pyregov +3 more
doaj +1 more source
Improved renal recovery in patients with atypical hemolytic uremic syndrome following rapid initiation of eculizimab treatment [PDF]
, 2016 Background: Eculizumab is approved for atypical hemolytic uremic syndrome (aHUS). Guidelines discuss the importance of prompt treatment. We report a post hoc analysis investigating the effect of baseline factors, including patient characteristics and ...
Ardissimo, Gianluigi +5 more
core +2 more sources
Atypical hemolytic uremic syndrome: a syndrome in need of clarity [PDF]
Clinical Kidney Journal, 2018 Atypical hemolytic uremic syndrome (aHUS) is a thrombotic microangiopathy (TMA) originally understood to be limited to renal and hematopoietic involvement. Whereas aberrations in complement regulatory proteins (CRPs), C3 or complement factor B (CFB) are detected in ∼60% of patients, a complement-derived pathogenesis that reflects dysregulation of the ...
openaire +3 more sources
Factor H-related protein 1 neutralizes anti-factor H autoantibodies in autoimmune hemolytic uremic syndrome. [PDF]
, 2011 The autoimmune form of atypical hemolytic uremic syndrome (HUS) is characterized by circulating autoantibodies against the complement regulator factor H, and is often associated with deficiency of the factor H-related proteins CFHR1 and CFHR3.
Abarrategui-Garrido, C. +5 more
core +1 more source
Journal of the American Society of Nephrology, 2019 BACKGROUND Atypical hemolytic uremic syndrome (HUS) is associated with high recurrence rates after kidney transplant, with devastating outcomes. In late 2011, experts in France recommended the use of highly individualized complement blockade-based ...
J. Zuber +44 more
semanticscholar +1 more source
Anti factor H autoantibodies block C-terminal recognition function of factor H in hemolytic uremic syndrome [PDF]
, 2007 The atypical form of the kidney disease hemolytic uremic syndrome (aHUS) is associated with defective complement regulation. In addition to mutations in complement regulators, factor H (FH)-specific autoantibodies have been reported for aHUS patients ...
Dahse, H. M. +4 more
core +1 more source
The major autoantibody epitope on factor H in atypical hemolytic uremic syndrome is structurally different from its homologous site in factor H-related protein 1, supporting a novel model for induction of autoimmunity in this disease [PDF]
, 2015 Atypical hemolytic uremic syndrome (aHUS) is characterized by complement attack against host cells due to mutations in complement proteins or autoantibodies against complement factor H (CFH).
Abarrategui-Garrido +59 more
core +1 more source
American Journal of Kidney Diseases, 2016 BACKGROUND Atypical hemolytic uremic syndrome (aHUS) is a rare genetic life-threatening disease of chronic uncontrolled complement activation leading to thrombotic microangiopathy (TMA) and severe end-organ damage.
F. Fakhouri +5 more
semanticscholar +1 more source
JACC: Case Reports, 2021 A young woman presented with an acute ST-segment elevation myocardial infarction. Her clinical course was complicated by cardiogenic shock and acute renal failure. Work-up revealed thrombocytopenia and hemolytic anemia.
Edward Chau, MD, MS +8 more
doaj
Global Journal of Transfusion Medicine, 2018 Atypical hemolytic uremic syndrome (aHUS) is a clinical diagnosis characterized by a triad of microangiopathic hemolytic anemia, thrombocytopenia, and renal dysfunction. Postoperative aHUS in nontransplant patients is a rare entity.
Anil Khetarpal +2 more
doaj +1 more source