Results 51 to 60 of about 24,341 (292)

How I treat thrombotic thrombocytopenic purpura and atypical haemolytic uraemic syndrome [PDF]

, 2014
Thrombotic thrombocytopenic purpura (TTP) and atypical haemolytic uraemic syndrome (aHUS) are acute, rare life-threatening thrombotic microangiopathies that require rapid diagnosis and treatment.
Goodship, T, Scully, M
core   +1 more source

Atypical Hemolytic Uremic Syndrome after SARS-CoV-2 Infection: Report of Two Cases

International Journal of Environmental Research and Public Health, 2022
Atypical hemolytic uremic syndrome (aHUS) is a life-threatening disease causing systemic thrombotic microangiopathy (TMA) due to the fact of complement dysregulation.
Iwona Smarz-Widelska, Małgorzata Syroka-Główka, Joanna Janowska-Jaremek, M. Koziol, W. Załuska   +4 more
semanticscholar   +1 more source

Pregnancy in Women with Atypical Hemolytic Uremic Syndrome [PDF]

Nephron, 2021
<b><i>Background:</i></b> Pregnancy outcomes in patients with atypical hemolytic uremic syndrome (aHUS) are not well-documented. Here, we present characteristics of and outcomes for patients with aHUS who became pregnant while enrolled in the Global aHUS Registry.
Benjamin Miller, Marie Scully, Imad Al-Dakkak, Marie-Pierre Caby-Tosi, Global aHUS Registry, Gianluigi Ardissino, Fadi Fakhouri, Eric Rondeau   +7 more
openaire   +2 more sources

An expert discussion on the atypical hemolytic uremic syndrome nomenclature-identifying a road map to precision: a report of a National Kidney Foundation Working Group. [PDF]

The term atypical hemolytic uremic syndrome has been in use since the mid-1970s. It was initially used to describe the familial or sporadic form of hemolytic uremic syndrome as opposed to the epidemic, typical form of the disease. Over time, the atypical
Burwick, R., Cataland, S., Chaturvedi, S., Cook, H.T., Cuker, A., Dixon, B.P., Fakhouri, F., Feldman, D.L., Hingorani, S.R., Java, A., Kavanagh, D., Leung, N., Licht, C., Nester, C.M., Noris, M., O'Shaughnessy, M.M., Parikh, S.V., Peyandi, F., Remuzzi, G., Smith, RJH, Sperati, C.J., van de Kar, NCAJ, Vivarelli, M., Waldman, M., Walker, P.   +24 more
core   +4 more sources

Atypical hemolytic uremic syndrome induced by SARS-CoV2 infection in infants with EXOSC3 mutation

Pediatric nephrology (Berlin, West), 2022
Atypical hemolytic uremic syndrome (aHUS) is a rare disease characterized by systemic thrombotic microangiopathy mainly in the kidneys and mostly due to genetic disorders leading to uncontrolled activation of the complement system.
Chantal Van Quekelberghe, Kay Latta, Steffen Kunzmann, M. Grohmann, M. Hansen   +4 more
semanticscholar   +1 more source

Complement and the atypical hemolytic uremic syndrome in children [PDF]

Pediatric Nephrology, 2008
AbstractOver the past decade, atypical hemolytic uremic syndrome (aHUS) has been demonstrated to be a disorder of the regulation of the complement alternative pathway. Among approximately 200 children with the disease, reported in the literature, 50% had mutations of the complement regulatory proteins factor H, membrane cofactor protein (MCP) or factor
Véronique Frémeaux-Bacchi, Marina Noris, Chantal Loirat   +2 more
openaire   +3 more sources

Atypical Hemolytic Uremic Syndrome

Pediatric Clinics of North America, 2018
Atypical hemolytic uremic syndrome is a rare life-threatening disease of unregulated complement activation. Untreated, the prognosis is generally poor; more than one-half of patients die or develop end-stage renal disease within 1 year. Atypical hemolytic uremic syndrome is characterized by thrombotic microangiopathy with evidence of hemolysis ...
Bradley P. Dixon, Ralph A. Gruppo
openaire   +5 more sources

Pregnancy-triggered atypical hemolytic uremic syndrome (aHUS): a Global aHUS Registry analysis

JN. Journal of Nephrology (Milano. 1992), 2021
Atypical hemolytic uremic syndrome (aHUS) is a rare disease in which uncontrolled terminal complement activation leads to systemic thrombotic microangiopathy (TMA).
F. Fakhouri, M. Scully, G. Ardissino, I. Al-Dakkak, Benjamin Miller, E. Rondeau   +5 more
semanticscholar   +1 more source

CFHR Gene Variations Provide Insights in the Pathogenesis of the Kidney Diseases Atypical Hemolytic Uremic Syndrome and C3 Glomerulopathy.

Journal of the American Society of Nephrology, 2020
Sequence and copy number variations in the human CFHR-Factor H gene cluster comprising the complement genes CFHR1, CFHR2, CFHR3, CFHR4, CFHR5, and Factor H are linked to the human kidney diseases atypical hemolytic uremic syndrome (aHUS) and C3 ...
P. Zipfel, T. Wiech, E. Stea, C. Skerka
semanticscholar   +1 more source

Phenotypic manifestation of homozygous partial deletion of the chromosome 1 segment spanning CFHR3 region

Медицинская иммунология, 2020
This article presents two clinical cases of patients with a homozygous deletion of segment of chromosome 1, which covers regions of genes associated with complement factor H, in particular CFHR3.
I. A. Tuzankina, M. A. Bolkov, N. S. Zhuravleva, Yu. O. Vaseneva, Kh. Shinvari, O. V. Schipacheva   +5 more
doaj   +1 more source