A quantitative assessment of the prion risk associated with wastewater from carcase-handling facilities [PDF]
Wastewater from facilities processing livestock that may harbor transmissible spongiform encephalopathies (TSEs) infectivity is permitted under license for application to land where susceptible livestock may have access. Several previous risk assessments
Adkin, A. +2 more
core +4 more sources
Background Atypical scrapie was first identified in Norwegian sheep in 1998 and has subsequently been identified in many countries. Retrospective studies have identified cases predating the initial identification of this form of scrapie, and ...
Bellworthy Susan J +5 more
doaj +1 more source
Eradication of scrapie with selective breeding: are we nearly there? [PDF]
Background Following EU decision 2003/100/EC Member States have recently implemented sheep breeding programmes to reduce the prevalence of sheep with TSE susceptible prion genotypes.
Bossers, A. +18 more
core +1 more source
Classical and Atypical Scrapie in Sheep and Goats
Scrapie is a naturally occurring transmissible spongiform encephalopathy (TSE) in sheep, goats and moufflons almost worldwide and is known for about 270 years.
Fast, Christine, Groschup, Martin H.
core +1 more source
Atypical/Nor98 scrapie in the Basque Country: a case report of eight outbreaks
Background Since 2002, an active surveillance program for transmissible spongiform encephalopathy in small ruminants in European Union countries allowed identification of a considerable number of atypical cases with similarities to the previously ...
Minguijón Esmeralda +8 more
doaj +1 more source
State-of-the-art review of goat TSE in the European Union, with special emphasis on PRNP genetics and epidemiology [PDF]
Scrapie is a fatal, neurodegenerative disease of sheep and goats. It is also the earliest known member in the family of diseases classified as transmissible spongiform encephalopathies (TSE) or prion diseases, which includes Creutzfeldt-Jakob disease in ...
Olivier Andreéoletti +54 more
core +1 more source
Advanced survival models for risk-factor analysis in scrapie [PDF]
Because of the confounding effects of long incubation duration and flock management, accurate epidemiological studies of scrapie outbreaks are difficult to carry out.
Joly, Pierre +6 more
core +1 more source
Sheep scrapie and deer rabies in England prior to 1800
Eighteenth-century England witnessed the emergence of two neurological diseases in animals. Scrapie, a transmissible spongiform encephalopathy, is a fatal neurodegenerative disease of sheep and goats that appears in classical and atypical forms.
Anthony Ness +2 more
doaj +1 more source
Archival search for historical atypical scrapie in sheep reveals evidence for mixed infections. [PDF]
Natural scrapie in sheep occurs in classical and atypical forms, which may be distinguished on the basis of the associated neuropathology and properties of the disease-associated prion protein on Western blots. First detected in 1998, atypical scrapie is
Chong A +6 more
europepmc +2 more sources
Caprine prion gene polymorphisms are associated with decreased incidence of classical scrapie in goat herds in the United Kingdom [PDF]
The application of genetic breeding programmes to eradicate transmissible spongiform encephalopathies in goats is an important aim for reasons of animal welfare as well as human food safety and food security. Based on the positive impact of Prnp genetics
Bossers, A. +33 more
core +1 more source

