Results 21 to 30 of about 173,798 (150)

Classical BSE prions emerge from asymptomatic pigs challenged with atypical/Nor98 scrapie

Scientific Reports, 2021
Pigs are susceptible to infection with the classical bovine spongiform encephalopathy (C-BSE) agent following experimental inoculation, and PrPSc accumulation was detected in porcine tissues after the inoculation of certain scrapie and chronic wasting ...
Belén Marín, Alicia Otero, Séverine Lugan, Juan Carlos Espinosa, Alba Marín-Moreno, Enric Vidal, Carlos Hedman, Antonio Romero, Martí Pumarola, Juan J. Badiola, Juan María Torres, Olivier Andréoletti, Rosa Bolea   +12 more
doaj   +1 more source

Detection of classical BSE prions in asymptomatic cows after inoculation with atypical/Nor98 scrapie

Veterinary Research, 2023
The emergence of bovine spongiform encephalopathy (BSE) prions from atypical scrapie has been recently observed upon experimental transmission to rodent and swine models. This study aimed to assess whether the inoculation of atypical scrapie could induce
Marina Betancor, Belén Marín, Alicia Otero, Carlos Hedman, Antonio Romero, Tomás Barrio, Eloisa Sevilla, Jean-Yves Douet, Alvina Huor, Juan José Badiola, Olivier Andréoletti, Rosa Bolea   +11 more
doaj   +1 more source

Prion Evolvability and the Hazard of Atypical Scrapie in Small Ruminants

Open Veterinary Science, 2020
Observations on strain behaviour and direct demonstrations of natural selection establish that the scrapie agent and prions in general are able to evolve.
Adams David B.
doaj   +1 more source

Transmissibility of atypical scrapie in ovine transgenic mice: major effects of host prion protein expression and donor prion genotype. [PDF]

PLoS ONE, 2009
Atypical scrapie or Nor98 has been identified as a transmissible spongiform encephalopathy (TSE) that is clearly distinguishable from classical scrapie and BSE, notably regarding the biochemical features of the protease-resistant prion protein PrP(res ...
Jean-Noël Arsac, Dominique Bétemps, Eric Morignat, Cécile Féraudet, Anna Bencsik, Denise Aubert, Jacques Grassi, Thierry Baron   +7 more
doaj   +1 more source

A descriptive study of the prevalence of atypical and classical scrapie in sheep in 20 European countries

BMC Veterinary Research, 2008
Background The development of active surveillance programmes for transmissible spongiform encephalopathies of small ruminants across Europe has led to the recent identification of a previously undetected form of ovine prion disease, 'atypical' scrapie ...
Calavas Didier, Nöremark Maria, Tongue Sue C, Fediaevsky Alexandre, Ru Giuseppe, Hopp Petter   +5 more
doaj   +1 more source

B‐cell leukemia in an adult sheep

Veterinary Clinical Pathology, Volume 52, Issue 4, Page 716-721, December 2023., 2023
Abstract B‐cell leukemia is a rare form of hematologic neoplasia in sheep, especially in adult animals. We present a case report of a 5‐year‐old WhiteFace Sheep wether with suspected acute lymphoblastic leukemia. The patient, a second‐generation relative of ewes experimentally inoculated with atypical scrapie, exhibited acute lethargy and loss of ...
Adriana P. Furtado, Lindsay M. Fry, Lindsay M. W. Piel, Reginaldo G. Bastos, David A. Schneider, Mara S. Varvil   +5 more
wiley   +1 more source

Demographic risk factors for classical and atypical scrapie in Great Britain [PDF]

, 2007
Following the bovine spongiform encephalopathy (BSE) crisis, the European Union has introduced policies for eradicating transmissible spongiform encephalopathies (TSEs), including scrapie, from large ruminants. However, recent European Union surveillance
Noel D McCarthy (16058201), Green, Darren, McCarthy, N.D., Kao, Rowland R, Kao, RR, del Rio Vilas, V.J., Kiss, I.Z., del Rio Vilas, Victor J, Kiss, IZ, del Rio Vilas, VJ, McCarthy, Noel D, Colin P D Birch (16058198), Darren M Green (16058192), Jethro Johnson (12099290), Kao, R.R., Victor J del Rio Vilas (16058195), Green, D.M., Johnson, J., McCarthy, ND, Istvan Kiss (4462126), Kiss, Istvan Z, Johnson, Jethro, Birch, CPD, Green, DM, Johnson, J, Birch, CP, Rowland R Kao (16058204), Birch, C.P.D., Birch, Colin P D   +28 more
core   +1 more source

The European Union summary report on surveillance for the presence of transmissible spongiform encephalopathies (TSE) in 2022

EFSA Journal, Volume 21, Issue 11, November 2023., 2023
Abstract This report presents the results of surveillance on transmissible spongiform encephalopathies (TSE) in cattle, sheep, goats, cervids and other species, and genotyping in sheep and goats, carried out in 2022 by 27 Member States (MS, EU27), the United Kingdom (in respect of Northern Ireland [XI]) and other eight non‐EU reporting countries ...
European Food Safety Authority (EFSA)
wiley   +1 more source

An economic evaluation of preclinical testing strategies compared to the compulsory scrapie flock scheme in the control of classical scrapie [PDF]

, 2012
Cost-benefit is rarely combined with nonlinear dynamic models when evaluating control options for infectious diseases. The current strategy for scrapie in Great Britain requires that all genetically susceptible livestock in affected flocks be culled ...
Fiona Houston, Kao, R., Boden, L., Kao, Rowland, Fryer Helen, Hawkins, Neil, Helen Fryer, Handel, I., Boden Lisa, Hawkins, N., Handel Ian, Ian Handel, Fryer, Helen, Houston Fiona, Kao Rowland, Handel, Ian, Hawkins Neil, Rowland Kao, Fryer, H., Boden, Lisa, Houston, Fiona, Lisa Boden, Houston, F., Neil Hawkins   +23 more
core   +1 more source

The prevalence of atypical scrapie in sheep from positive flocks is not higher than in the general sheep population in 11 European countries

BMC Veterinary Research, 2010
Background During the last decade, active surveillance for transmissible spongiform encephalopathies in small ruminants has been intensive in Europe. In many countries this has led to the detection of cases of atypical scrapie which, unlike classical ...
Liam Barry, Hautaniemi Maria, Poizat Renaud, Orge Leonor, Thorgeirsdottir Stefania, Ingravalle Francesco, Nöremark Maria, Maurella Cristiana, Fediaevsky Alexandre, Calavas Didier, Ru Giuseppe, Hopp Petter   +11 more
doaj   +1 more source