The European Union summary report on surveillance for the presence of transmissible spongiform encephalopathies (TSE) in 2023 [PDF]
EFSA JournalThis report presents the results of surveillance on transmissible spongiform encephalopathies in cattle, sheep, goats, cervids and other species, and genotyping in sheep and goats, carried out in 2023 by 27 Member States (MS, EU27), the United Kingdom ...
European Food Safety Authority (EFSA)
doaj +3 more sources
Practical Real-Time Quaking-Induced Conversion for Detecting Classical Bovine Spongiform Encephalopathy and Classical and Atypical Scrapie Prions [PDF]
PathogensReal-time quaking-induced conversion (RT-QuIC) is highly sensitive for prion detection; however, inhibitory factors present in tissue homogenates readily interfere with the assay.
Akio Suzuki +8 more
doaj +2 more sources
Atypical scrapie in sheep from a UK research flock which is free from classical scrapie [PDF]
BMC Veterinary Research, 2009 Background In the wake of the epidemic of bovine spongiform encephalopathy the British government established a flock of sheep from which scrapie-free animals are supplied to laboratories for research.
Ortiz-Pelaez Angel +9 more
doaj +2 more sources
Atypical Scrapie Prions from Sheep and Lack of Disease in Transgenic Mice Overexpressing Human Prion Protein [PDF]
Emerging Infectious Diseases, 2013 Public and animal health controls to limit human exposure to animal prions are focused on bovine spongiform encephalopathy (BSE), but other prion strains in ruminants may also have zoonotic potential.
Jonathan D.F. Wadsworth +11 more
doaj +2 more sources
Mapping PRNP Polymorphisms in Portuguese Serra da Estrela Ovine Populations: Insights into Scrapie Susceptibility and Farm Animal Improvement [PDF]
AnimalsScrapie (classical and atypical) susceptibility in sheep is strongly influenced by PRNP gene polymorphisms. In Portugal, limited data exist for native breeds such as Serra da Estrela, despite their relevance to animal conservation and food production ...
Soraia Rodrigues +8 more
doaj +2 more sources
First case of atypical scrapie in a goat in Japan [PDF]
Journal of Veterinary Medical Science, 2019 Yuichi Matsuura, Yoshifumi Iwamaru
exaly +2 more sources
The European Union summary report on surveillance for the presence of transmissible spongiform encephalopathies (TSE) in 2024. [PDF]
EFSA JABSTRACT This report presents results of surveillance on transmissible spongiform encephalopathies in bovines, sheep, goats, cervids and other species, and genotyping in sheep and goats, carried out in 2024 by 27 EU Member States (EU27, MS), the UK (in respect of Northern Ireland, (XI)) and 8 non‐EU reporting countries: Bosnia and Herzegovina, Iceland,
European Food Safety Authority (EFSA) +7 more
europepmc +2 more sources
The L108I polymorphism in mouse prion protein drives spontaneous disease and enhances transmission of atypical and classical prion strains. [PDF]
Brain PatholA single amino acid change (L108I) combined with PrP overexpression drives spontaneous atypical prion formation in mice, enabling also efficient propagation of diverse prion strains. This model allows studying how spontaneous prion diseases arise and provides powerful tools for investigating strain emergence, transmission barriers, and mechanisms ...
Eraña H +20 more
europepmc +2 more sources
A quantitative assessment of the amount of prion diverted to category 1 materials and wastewater during processing [PDF]
, 2013 In this article the development and parameterization of a quantitative assessment is described that estimates the amount of TSE infectivity that is present in a whole animal carcass (bovine spongiform encephalopathy [BSE] for cattle and classical ...
Adkin, A. +2 more
core +4 more sources
Evolutionary biology and the risk of scrapie disease in sheep [PDF]
Open Veterinary Journal, 2018 Scrapie in sheep occurs in two forms. Classical scrapie, along with chronic wasting disease in deer, differs from all other prion diseases in being contagious and occurring as propagating epidemics.
David Bruce Adams
doaj +1 more source