Results 51 to 60 of about 173,798 (150)

No temporal trends in the prevalence of atypical scrapie in British sheep, 2002–2006

BMC Veterinary Research, 2008
Background So-called atypical scrapie was first identified in Great Britain (GB) in 2002 following the introduction of wide-scale scrapie surveillance. In particular, abattoir and fallen stock surveys have been carried out in GB since 2002, with a total ...
del Rio Vilas Victor J, McIntyre K Marie, Gubbins Simon   +2 more
doaj   +1 more source

Atypical status of bovine spongiform encephalopathy in Poland: a molecular typing study [PDF]

, 2008
The aim of this study was to analyze molecular features of protease-resistant prion protein (PrPres) in Western blots of BSE cases diagnosed in Poland with respect to a possible atypical status.
Polak, M.P., Zmudzinski, J.F., Jacobs, J.G., Langeveld, J.P.M.   +3 more
core   +1 more source

Clinical findings in two cases of atypical scrapie in sheep: a case report

BMC Veterinary Research, 2007
Background Atypical scrapie is a recently recognised form of transmissible spongiform encephalopathy of sheep that differs from classical scrapie in its neuropathological and biochemical features.
Chaplin Melanie, Everitt Sharon, Bracegirdle John, Bone Gemma, Davis Andrew, Konold Timm, Saunders Ginny C, Cawthraw Saira, Simmons Marion M   +8 more
doaj   +1 more source

PrP^Sc spreading patterns in the brain of sheep linked to different prion types

Veterinary Research, 2011
Scrapie in sheep and goats has been known for more than 250 years and belongs nowadays to the so-called prion diseases that also include e.g. bovine spongiform encephalopathy in cattle (BSE) and Creutzfeldt-Jakob disease in humans. According to the prion
Wemheuer Wiebke M, Benestad Sylvie L, Wrede Arne, Wemheuer Wilhelm E, Brenig Bertram, Bratberg Bjørn, Schulz-Schaeffer Walter J   +6 more
doaj   +1 more source

Skin-derived dendritic cells acquire and degrade the scrapie agent following in vitro exposure [PDF]

, 2005
The accumulation of the scrapie agent in lymphoid tissues following inoculation via the skin is critical for efficient neuroinvasion, but how the agent is initially transported from the skin to the draining lymph node is not known. Langerhans cells (LCs)
Hopkins, John, Mabbott, Neil; id_orcid, John Hopkins, Joanne Mohan, Mohan, Joanne, Neil A. Mabbott   +5 more
core   +1 more source

Transgenic Mice Expressing Porcine Prion Protein Resistant to Classical Scrapie but Susceptible to Sheep Bovine Spongiform Encephalopathy and Atypical Scrapie

Emerging Infectious Diseases, 2009
How susceptible pigs are to infection with sheep prions is unknown. We show, through transmission experiments in transgenic mice expressing porcine prion protein (PrP), that the susceptibility of this mouse model to bovine spongiform encephalopathy (BSE)
Juan-Carlos Espinosa, María-Eugenia Herva, Olivier Andréoletti, Danielle Padilla, Caroline Lacroux, Hervé Cassard, Isabelle Lantier, Joaquin Castilla, Juan-María Torres   +8 more
doaj   +1 more source

Scrapie-resistant sheep show certain coat colour characteristics [PDF]

, 2009
Susceptibility to scrapie is known to be associated with polymorphisms at the prion protein (PrP) gene, and this association is the basis of current selective programmes implemented to control scrapie in many Countries.
White, I, Brotherstone, S., White, I., Sawalha, RM, Villanueva, B., Villanueva, B, Wilson, A. J., Brotherstone, S, Wilson, AJ, Bell, L., Bell, L, Sawalha, R. M.   +11 more
core   +1 more source

Gene expression profiling en association with prion-related lesions in the medulla oblongata of symptomatic natural scrapie animals. [PDF]

, 2011
The pathogenesis of natural scrapie and other prion diseases remains unclear. Examining transcriptome variations in infected versus control animals may highlight new genes potentially involved in some of the molecular mechanisms of prion-induced ...
Bossers, A., Rosa Bolea, Hicham Filali, Varona, L., Filalil, Hicham, Harders, F., Inmaculada Martin-Burriel, Alex Bossers, Zaragoza, P., Badiola, J.J., Juan J. Badiola, Bossers, Alex, Pumarola i Batlle, Martí, Lyahyai, Jaber, Lyahyai, J., Martín Burriel, Inmaculada, Pilar Zaragoza, Juan J Badiola, Bolea, Rosa, Filali, H., Bolea, R., Acín, Cristina, Luis Varona, Frank Harders, Filali, Hicham, Pumarola, M., Harders, Frank, Zaragoza, Pilar, Badiola, Juan J, Varona, Luis, Martí Pumarola, Jaber Lyahyai, Martin-Burriel, I., Badiola, Juan José, Pumarola, Martí   +34 more
core   +2 more sources

Possible alignment of the EU BSE surveillance with the new WOAH provisions

EFSA Journal, Volume 24, Issue 4, April 2026.
Abstract The European Commission requested the assessment of the capacity of the surveillance provisions of the World Organization for Animal Health (WOAH) to detect bovine spongiform encephalopathy (BSE) cases (C‐, H‐ and L‐type) in the European Union (EU) and to propose if any current EU surveillance provisions should be kept.
EFSA Panel on Animal Health and Welfare (AHAW), Søren Saxmose Nielsen, Julio Alvarez, Anette Boklund, Sabine Dippel, Fernanda Dórea, Jordi Figuerola, Mette S. Herskin, Virginie Michel, Miguel Angel Miranda Chueca, Eleonora Nannoni, Anja B. Riber, Karl Stahl, Jan Arend Stegeman, Hans‐Hermann Thulke, Frank Tuyttens, Christoph Winckler, Mark Arnold, Christian Ducrot, John Griffin, Giuseppe Ru, Marion Simmons, Sean Ashe, Angel Ortiz‐ Pelaez, Kamela Kryemadhi, Romolo Nonno   +25 more
wiley   +1 more source

Five novel PRNP gene polymorphisms and their potential effect on Scrapie susceptibility in three native Ethiopian sheep breeds

BMC Veterinary Research, 2020
Background Classical scrapie susceptibility in sheep has been linked to three polymorphisms at codon 136, 154, and 171 in the prion protein gene (PRNP) whereas atypical scrapie susceptibility is related to polymorphisms at codon 141.
Eden Yitna Teferedegn, Yalcin Yaman, Cemal Un   +2 more
doaj   +1 more source