Results 61 to 70 of about 26,365 (298)

Small Extracellular Vesicles‐Derived Circ6718 Unlocks Stromal Remodeling and Serves as a Biomarker in Gastric Cancer

open access: yesAdvanced Science, EarlyView.
sEVs‐circ6718 serves as a promising serum biomarker for gastric cancer early diagnosis and prognosis, promoting malignant transformation in gastric cancer cells and GC‑MSC differentiation into CAFs. sEVs‑circ6718 holds potential as a biomarker for the early diagnosis and prognostic assessment of gastric cancer.
Fan Zhang   +7 more
wiley   +1 more source

Authentic tasks in e-learning designs

open access: yes, 2005
Constructivist approaches to learning design, while gaining increased acceptance in the higher education community, are the exception rather than the rule in the majority of web-based courses currently offered by universities throughout the world.
Herrington, J.
core   +1 more source

UCHL3 Regulates Subgenomic Flaviviral RNA Condensates to Promote Virus Propagation

open access: yesAdvanced Science, EarlyView.
ABSTRACT Flavivirus subgenomic RNAs (sfRNAs) antagonise antiviral defences, yet how sfRNAs are organized and maintained in cells remains poorly understood. Here we identify ubiquitin C‐terminal hydrolase L3 (UCHL3) as a post‐translational regulator of flavivirus sfRNA stability and function.
Oscar Trejo‐Cerro   +7 more
wiley   +1 more source

Accomplishing authentic writing tasks: Ventures into academic publication by Ecuadorian EFL teachers

open access: yesIndonesian Journal of Applied Linguistics, 2019
Academic writing and subsequent publishing have become an important part of the career advancement and professional development of those engaged in English language teaching worldwide.
Agnes Orosz   +3 more
doaj   +1 more source

Astrocytic Phenotypic Switching in Posterior Piriform Cortex Orchestrates Bone Cancer Pain–Depression Comorbidity via Purinergic–Noradrenergic Signaling

open access: yesAdvanced Science, EarlyView.
Bone cancer pain and depression share a common origin: astrocytic A2‐to‐A1 transition in the posterior piriform cortex. This phenotypic shift disrupts the ATP–adenosine–A2AR–norepinephrine axis, simultaneously driving nociceptive and affective dysfunction.
Jiang‐Ping Liu   +14 more
wiley   +1 more source

Authentic conditions for authentic assessment: Aligning task and assessment

open access: yes, 2006
Despite major discussion and consideration of authentic assessment through the 1990s, little progress appears to have been made towards its widespread adoption in higher education.
Herrington, J., Herrington, A.
core  

Unifying Composition and Process Design: A Heterogeneous Graph Neural Network for Discovering High‐Performance Cu Alloys

open access: yesAdvanced Science, EarlyView.
By overcoming the fixed‐path limitations of conventional machine learning, a heterogeneous graph neural network fundamentally reconstructs material data representation. Integrating variable processing sequences with intrinsic elemental features, this framework enables exploratory optimization across high‐dimensional spaces.
Jie Yin   +12 more
wiley   +1 more source

Authentic E-Learning in higher education: Design principles for authentic learning environments and tasks

open access: yes, 2006
With many learners failing to engage with didactic and outmoded instructional methods, and unwilling to use technology that simply replicates the one-way transfer of information from teacher to student, authentic learning designs have the potential to ...
Herrington, J.
core  

Phase Fraction Modulation Enhances Li+/Na+ Diffusion Disparity in Spent LiFePO4 Cathodes for Efficient Lithium Extraction from Brine

open access: yesAdvanced Science, EarlyView.
A direct cascaded utilization strategy for spent LiFePO4 batteries efficiently extracts lithium from brine, embodying the “urban mining” concept. Phase fraction modulation revealed its significant impact on local bond lengths of crystal structure and the Li/Na diffusion energy barrier, identifying the best material (Li0.19FePO4) for lithium extraction.
Ruiqi Yin   +7 more
wiley   +1 more source

A Multi-Task Adversarial Attack against Face Authentication

open access: yesACM Transactions on Multimedia Computing, Communications, and Applications
Deep learning-based identity management systems, such as face authentication systems, are vulnerable to adversarial attacks. However, existing attacks are typically designed for single-task purposes, which means they are tailored to exploit vulnerabilities unique to the individual target rather than being adaptable for multiple users or systems.
Hanrui Wang 0005   +4 more
openaire   +2 more sources

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