Results 11 to 20 of about 242,290 (361)

The detectable anti-interferon-γ autoantibodies in COVID-19 patients may be associated with disease severity

Virology Journal, 2023
Background Neutralizing anti-interferon (IFN)-γ autoantibodies are linked to adult-onset immunodeficiency and opportunistic infections. Methods To explore whether anti-IFN-γ autoantibodies are associated with disease severity of coronavirus disease 2019 (
Po-Ku Chen, Kai-Jieh Yeo, Shih-Hsin Chang, Tsai-Ling Liao, Chia-Hui Chou, Joung-Liang Lan, Ching-Kun Chang, Der-Yuan Chen   +7 more
doaj   +1 more source

The presence of autoantibodies is associated with improved overall survival in lung cancer patients

Frontiers in Oncology, 2023
ObjectiveAutoantibodies have been reported to be associated with cancers. As a biomarker, autoantibodies have been widely used in the early screening of lung cancer.
Keying Jing, Huijuan Zhao, Jun Cai, Lianlian Chen, Peiming Zheng, Libo Ouyang, Gang Li, Rong Wang   +7 more
doaj   +1 more source

Physiological Changes in the Levels of Anti-Cytokine Autoantibodies in Early Pregnancy Are Missing in Pregnant Women with Hashimoto’s Thyroiditis

Journal of Immunology Research, 2023
T helper type 1 (Th1) and inflammatory cytokines play essential roles in early pregnancy and also in the pathogenesis of Hashimoto’s thyroiditis (HT).
Szabina Erdő-Bonyár, Diána Simon, Anna Bajnok, Jasper Nörenberg, Tímea Serény-Litvai, Ákos Várnagy, Kálmán Kovács, Eszter Hantosi, Emese Mezősi, Tímea Berki   +9 more
doaj   +1 more source

Multiplex giant magnetoresistive biosensor microarrays identify interferon-associated autoantibodies in systemic lupus erythematosus. [PDF]

, 2016
High titer, class-switched autoantibodies are a hallmark of systemic lupus erythematosus (SLE). Dysregulation of the interferon (IFN) pathway is observed in individuals with active SLE, although the association of specific autoantibodies with chemokine ...
Baechler, Emily C, Balboni, Imelda M, Diep, Vivian K, Haddon, D James, Hall, Drew A, Lee, Jung-Rok, Petri, Michelle, Price, Jordan V, Utz, Paul J, Wand, Hannah E, Wang, Shan X   +10 more
core   +2 more sources

Increased immune complexes of hypocretin autoantibodies in narcolepsy. [PDF]

PLoS ONE, 2010
BACKGROUND: Hypocretin peptides participate in the regulation of sleep-wake cycle while deficiency in hypocretin signaling and loss of hypocretin neurons are causative for narcolepsy-cataplexy.
Aude Deloumeau, Sophie Bayard, Quentin Coquerel, Pierre Déchelotte, Christine Bole-Feysot, Bertrand Carlander, Valérie Cochen De Cock, Sergueï O Fetissov, Yves Dauvilliers   +8 more
doaj   +1 more source

Autoantibodies against retinal proteins in paraneoplastic and autoimmune retinopathy [PDF]

, 2004
BACKGROUND: Autoimmune retinal degeneration may occur in patients who present with sudden or, less commonly, subacute loss of vision of retinal origin, associated with an abnormal ERG, through the action of autoantibodies against retinal proteins.
AH Milam, B Lei, CE Thirkill, DM Jacobson, G Adamus, G Adamus, G Adamus, G Adamus, G Adamus, G Adamus, G Adamus, G Ren, G Tezel, Gaoying Ren, Grazyna Adamus, H Ohguro, H Ohguro, I Maruyama, JB Mizener, JL Keltner, JL Keltner, JL Keltner, JR Heckenlively, MA Murphy, MJ Potter, MR Stanford, MS Savchenko, R Peek, R Peek, Richard G Weleber, SM Whitcup, YH Yoon   +31 more
core   +3 more sources

Clinical relevance of silent red blood cell autoantibodies. [PDF]

, 2017
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Alessandri, C, Caputo, Md, Colafigli, G, Coluzzi, S, De Propris, Ms, Foà, R, Giovannetti, G, Girelli, G, Guarini, Ar, Mauro, Fr, Pepe, S, Porrazzo, M, Riemma, C, Trastulli, F, Valesini, G   +14 more
core   +1 more source

Genetics and autoantibodies

Immunologic Research, 2013
Autoimmune diseases (ADs) are chronic conditions initiated by the loss of immunological tolerance to self-antigens. The pathogenic hypothesis comprises a complex interaction between genetic, environmental and hormonal factors that interact with an individual over time generating a dysregulation of the immune system leading to disease development ...
Guido Valesini, Fulvia Ceccarelli, Juan-Manuel Anaya, Carlo Perricone, Yehuda Shoenfeld, Yehuda Shoenfeld, Nancy Agmon-Levin   +6 more
openaire   +4 more sources

Lymphocytotoxic Autoantibodies [PDF]

, 2007
Anti-lymphocytic antibodies (anti-LCA) are detected in patients with systemic lupus erythematosus (SLE) with a prevalence ranging from 60–90%. LCA detection is associated with nephritis and neurologic disorders in these patients, and high rates of LCA occur during phases of active SLE.
Renaudineau, Yves, Pers, Jacques-Olivier, Youinou, Pierre   +2 more
openaire   +4 more sources

Extrapancreatic autoantibody profiles in type I diabetes. [PDF]

PLoS ONE, 2012
Type I diabetes (T1D) is an autoimmune disease characterized by destruction of insulin-producing β-cells in the pancreas. Although several islet cell autoantigens are known, the breadth and spectrum of autoantibody targets has not been fully explored ...
Peter D Burbelo, Evan E Lebovitz, Kathleen E Bren, Ahmad Bayat, Scott Paviol, Janet M Wenzlau, Katherine J Barriga, Marian Rewers, David M Harlan, Michael J Iadarola   +9 more
doaj   +1 more source