Results 11 to 20 of about 139,183 (310)

Autoantibodies Against Factor B and Factor H Without Pathogenic Effects in a Patient with Immune Complex-Mediated Membranoproliferative Glomerulonephritis [PDF]

open access: yesBiomedicines
Background: Membranoproliferative glomerulonephritis (MPGN) is an umbrella term for chronic disorders affecting the glomeruli. MPGN is often accompanied by the presence of autoantibodies against complement components.
Alexandra T. Matola   +6 more
doaj   +2 more sources

Malignancy-Associated Membranous Nephropathy with Positive Anti-PLA2R Autoantibodies: Coincidence or Connection

open access: yesCase Reports in Nephrology and Dialysis, 2021
Membranous nephropathy (MN) is currently classified as either primary – often associated with positive anti-phospholipase-A2 receptor (PLA2R) autoantibodies – or as secondary – associated with malignancy, infection, medications, or autoimmune disease. We
Lyle W. Baker   +3 more
doaj   +1 more source

Romiplostim use in pregnant women with immune thrombocytopenia

open access: yesAmerican Journal of Hematology, Volume 98, Issue 1, Page 31-40, January 2023., 2023
Abstract Treatment for immune thrombocytopenia (ITP) in pregnancy is hampered by the lack of fetal safety evidence of maternally‐administered medications. The Pregnancy Surveillance Program (PSP) collected patient information from 2017–2020 for pregnancy, birth outcomes, and adverse events (AEs) for 186 women exposed to romiplostim from 20 days before ...
James B. Bussel   +7 more
wiley   +1 more source

Increased immune complexes of hypocretin autoantibodies in narcolepsy. [PDF]

open access: yesPLoS ONE, 2010
BACKGROUND: Hypocretin peptides participate in the regulation of sleep-wake cycle while deficiency in hypocretin signaling and loss of hypocretin neurons are causative for narcolepsy-cataplexy.
Aude Deloumeau   +8 more
doaj   +1 more source

The presence of autoantibodies is associated with improved overall survival in lung cancer patients

open access: yesFrontiers in Oncology, 2023
ObjectiveAutoantibodies have been reported to be associated with cancers. As a biomarker, autoantibodies have been widely used in the early screening of lung cancer.
Keying Jing   +7 more
doaj   +1 more source

Lymphocytotoxic Autoantibodies [PDF]

open access: yes, 2007
Anti-lymphocytic antibodies (anti-LCA) are detected in patients with systemic lupus erythematosus (SLE) with a prevalence ranging from 60–90%. LCA detection is associated with nephritis and neurologic disorders in these patients, and high rates of LCA occur during phases of active SLE.
Renaudineau, Yves   +2 more
openaire   +5 more sources

Genetics and autoantibodies

open access: yesImmunologic Research, 2013
Autoimmune diseases (ADs) are chronic conditions initiated by the loss of immunological tolerance to self-antigens. The pathogenic hypothesis comprises a complex interaction between genetic, environmental and hormonal factors that interact with an individual over time generating a dysregulation of the immune system leading to disease development ...
Guido Valesini   +6 more
openaire   +4 more sources

COULD BE CONSIDERED SERUM ANTI-S-100 AUTOANTIBODIES A BIOMARKER IN PATIENTS WITH ACUTE NON-CARDIOEMBOLIC ISCHEMIC STROKE? [PDF]

open access: yesRomanian Medical Journal, 2018
In ischemic stroke patients there were found autoantibodies against brain epitopes. The presence of anti-S-100 autoantibodies may reflect alteration and dysfunction of the blood-brain barrier.
Inimioara Mihaela Cojocaru   +3 more
doaj   +1 more source

Set Up for Failure: Pre-Existing Autoantibodies in Lung Transplant

open access: yesFrontiers in Immunology, 2021
Lung transplant patients have the lowest long-term survival rates compared to other solid organ transplants. The complications after lung transplantation such as primary graft dysfunction (PGD) and ultimately chronic lung allograft dysfunction (CLAD) are
Alexander McQuiston   +6 more
doaj   +1 more source

Extrapancreatic autoantibody profiles in type I diabetes. [PDF]

open access: yesPLoS ONE, 2012
Type I diabetes (T1D) is an autoimmune disease characterized by destruction of insulin-producing β-cells in the pancreas. Although several islet cell autoantigens are known, the breadth and spectrum of autoantibody targets has not been fully explored ...
Peter D Burbelo   +9 more
doaj   +1 more source

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