Results 11 to 20 of about 139,183 (310)
Autoantibodies Against Factor B and Factor H Without Pathogenic Effects in a Patient with Immune Complex-Mediated Membranoproliferative Glomerulonephritis [PDF]
Background: Membranoproliferative glomerulonephritis (MPGN) is an umbrella term for chronic disorders affecting the glomeruli. MPGN is often accompanied by the presence of autoantibodies against complement components.
Alexandra T. Matola+6 more
doaj +2 more sources
Membranous nephropathy (MN) is currently classified as either primary – often associated with positive anti-phospholipase-A2 receptor (PLA2R) autoantibodies – or as secondary – associated with malignancy, infection, medications, or autoimmune disease. We
Lyle W. Baker+3 more
doaj +1 more source
Romiplostim use in pregnant women with immune thrombocytopenia
Abstract Treatment for immune thrombocytopenia (ITP) in pregnancy is hampered by the lack of fetal safety evidence of maternally‐administered medications. The Pregnancy Surveillance Program (PSP) collected patient information from 2017–2020 for pregnancy, birth outcomes, and adverse events (AEs) for 186 women exposed to romiplostim from 20 days before ...
James B. Bussel+7 more
wiley +1 more source
Increased immune complexes of hypocretin autoantibodies in narcolepsy. [PDF]
BACKGROUND: Hypocretin peptides participate in the regulation of sleep-wake cycle while deficiency in hypocretin signaling and loss of hypocretin neurons are causative for narcolepsy-cataplexy.
Aude Deloumeau+8 more
doaj +1 more source
The presence of autoantibodies is associated with improved overall survival in lung cancer patients
ObjectiveAutoantibodies have been reported to be associated with cancers. As a biomarker, autoantibodies have been widely used in the early screening of lung cancer.
Keying Jing+7 more
doaj +1 more source
Lymphocytotoxic Autoantibodies [PDF]
Anti-lymphocytic antibodies (anti-LCA) are detected in patients with systemic lupus erythematosus (SLE) with a prevalence ranging from 60–90%. LCA detection is associated with nephritis and neurologic disorders in these patients, and high rates of LCA occur during phases of active SLE.
Renaudineau, Yves+2 more
openaire +5 more sources
Autoimmune diseases (ADs) are chronic conditions initiated by the loss of immunological tolerance to self-antigens. The pathogenic hypothesis comprises a complex interaction between genetic, environmental and hormonal factors that interact with an individual over time generating a dysregulation of the immune system leading to disease development ...
Guido Valesini+6 more
openaire +4 more sources
COULD BE CONSIDERED SERUM ANTI-S-100 AUTOANTIBODIES A BIOMARKER IN PATIENTS WITH ACUTE NON-CARDIOEMBOLIC ISCHEMIC STROKE? [PDF]
In ischemic stroke patients there were found autoantibodies against brain epitopes. The presence of anti-S-100 autoantibodies may reflect alteration and dysfunction of the blood-brain barrier.
Inimioara Mihaela Cojocaru+3 more
doaj +1 more source
Set Up for Failure: Pre-Existing Autoantibodies in Lung Transplant
Lung transplant patients have the lowest long-term survival rates compared to other solid organ transplants. The complications after lung transplantation such as primary graft dysfunction (PGD) and ultimately chronic lung allograft dysfunction (CLAD) are
Alexander McQuiston+6 more
doaj +1 more source
Extrapancreatic autoantibody profiles in type I diabetes. [PDF]
Type I diabetes (T1D) is an autoimmune disease characterized by destruction of insulin-producing β-cells in the pancreas. Although several islet cell autoantigens are known, the breadth and spectrum of autoantibody targets has not been fully explored ...
Peter D Burbelo+9 more
doaj +1 more source