Results 1 to 10 of about 137,428 (335)

Prediction of impending type 1 diabetes through automated dual-label measurement of proinsulin:C-peptide ratio [PDF]

, 2016
Background : The hyperglycemic clamp test, the gold standard of beta cell function, predicts impending type 1 diabetes in islet autoantibody-positive individuals, but the latter may benefit from less invasive function tests such as the proinsulin: C ...
Annelien Van Dalem, Bart Keymeulen, Belgian Diabetes Registry, Bruno Lapauw, Christophe De Block, Daniël Pipeleers, Eric V Balti, Eric Weber, Frans K Gorus, Ilse Vermeulen, Ilse Weets, Pascale Abrams, Pieter De Pauw, Pieter Gillard, Simke Demeester   +14 more
core   +16 more sources

Anti-Myxovirus Resistance Protein-1 Immunoglobulin A Autoantibody in Idiopathic Pulmonary Fibrosis

Canadian Respiratory Journal, 2022
Background. We have previously analysed serum autoantibody levels in patients with idiopathic pulmonary fibrosis (IPF), idiopathic nonspecific interstitial pneumonia (iNSIP), and healthy controls and identified the autoantibody against anti-myxovirus ...
Toru Arai, Masaki Hirose, Yoshimasa Hamano, Tomoko Kagawa, Akihiro Murakami, Hiroshi Kida, Atsushi Kumanogoh, Yoshikazu Inoue   +7 more
doaj   +1 more source

Effectiveness of pirfenidone in idiopathic pulmonary fibrosis according to the autoantibody status: a retrospective cohort study

BMC Pulmonary Medicine, 2021
Background Pirfenidone is an anti-fibrotic agent shown to slow the progression of idiopathic pulmonary fibrosis (IPF). However, its effectiveness in association with serological autoimmune features in IPF remains unclear.
Myung Jin Song, Sang Hoon Lee, Ji Ye Jung, Young Ae Kang, Moo Suk Park, Young Sam Kim, Joon Chang, Song Yee Kim   +7 more
doaj   +1 more source

Comprehensive autoantibody profiling in systemic autoimmunity by a highly-sensitive multiplex protein array

Frontiers in Immunology, 2023
Comprehensive autoantibody evaluation is essential for the management of autoimmune disorders. However, conventional methods suffer from poor sensitivity, low throughput, or limited availability.
Ai Kuzumi, Yuta Norimatsu, Kazuki M. Matsuda, Chihiro Ono, Taishi Okumura, Emi Kogo, Naoki Goshima, Naoki Goshima, Takemichi Fukasawa, Takemichi Fukasawa, Natsumi Fushida, Motoki Horii, Takashi Yamashita, Asako Yoshizaki-Ogawa, Kei Yamaguchi, Kei Yamaguchi, Takashi Matsushita, Shinichi Sato, Ayumi Yoshizaki, Ayumi Yoshizaki   +19 more
doaj   +1 more source

First-emerging islet autoantibody and glucose metabolism: search for type 1 diabetes subtypes

Endocrine Connections, 2022
Objective: Subtypes in type 1 diabetes pathogenesis have been implicated based on the first-appearing autoantibody (primary autoantibody). We set out to describe the glucose metabolism in preclinical diabetes in relation to the primary autoantibody in ...
Olli Helminen, Tytti Pokka, Susanna Aspholm, Jorma Ilonen, Olli G Simell, Mikael Knip, Riitta Veijola   +6 more
doaj   +1 more source

Correlates of survival after autoantibody reduction therapy for acute IPF exacerbations.

PLoS ONE, 2021
BackgroundNo medical treatment has proven efficacy for acute exacerbations of idiopathic pulmonary fibrosis (AE-IPF), and this syndrome has a very high mortality.
Tejaswini Kulkarni, Vincent G Valentine, Fei Fei, Thi K Tran-Nguyen, Luisa D Quesada-Arias, Takudzwa Mkorombindo, Huy P Pham, Sierra C Simmons, Kevin G Dsouza, Tracy Luckhardt, Steven R Duncan   +10 more
doaj   +1 more source

Comparison of clinical and laboratory characteristics in children with type 1 diabetes according to pancreatic autoantibodies [PDF]

Korean Journal of Pediatrics, 2010
Purpose:The purpose of this study was to determine whether there is any difference in the clinical and laboratory characteristics of patients with autoantibody-positive and patients with autoantibody-negative type 1 diabetes at initial presentation ...
Ji Hae Choi, Min Sun Kim, Chan Jong Kim, Jong Duk Kim, Dae-Yeol Lee   +4 more
doaj   +1 more source

Use of two methods to elute anti-IgG and anti-(IgG + C3d) type autoantibody from sensitized erythrocytes

Global Journal of Transfusion Medicine, 2018
Background: Autoimmune hemolytic anemia (AIHA) is an immunological disease caused by autoantibodies. Warm autoantibody mainly includes anti-IgG and anti-(IgG+C3d) type, which can cause direct antiglobulin test (DAT) positive.
He Ziyi, Hu Yingming, Cui Siping
doaj   +1 more source

Screening of endocrine organ-specific humoral autoimmunity in 47,XXY Klinefelter's syndrome reveals a significant increase in diabetes-specific immunoreactivity in comparison with healthy control men. [PDF]

, 2015
The aim of this study was to evaluate the frequency of humoral endocrine organ-specific autoimmunity in 47,XXY Klinefelter’s syndrome (KS) by investigating the autoantibody profile specific to type 1 diabetes (T1DM), Addison’s disease (AD), Hashimoto ...
ANZUINI, Antonella, GIANFRILLI, DANIELE, GRANATO, SIMONA, LENZI, Andrea, PANIMOLLE, FRANCESCA, RADICIONI, Antonio, Semeraro, A, TIBERTI, Claudio   +7 more
core   +1 more source

Autoantibody of NRIP, a novel AChR‐interacting protein, plays a detrimental role in myasthenia gravis

Journal of Cachexia, Sarcopenia and Muscle, 2021
Background Nuclear receptor interaction protein (NRIP) co‐localizes with acetylcholine receptor (AChR) at the neuromuscular junction (NMJ), and NRIP deficiency causes aberrant NMJ architecture.
Li‐Kai Tsai, I‐Hsin Chen, Chi‐Chao Chao, Hsueh‐Wen Hsueh, Hsin‐Hsiung Chen, Yun‐Hsin Huang, Rong‐Wei Weng, Tzu‐Yun Lai, Yi‐Chieh Tsai, Yeou‐Ping Tsao, Show‐Li Chen   +10 more
doaj   +1 more source