Results 1 to 10 of about 92,398 (247)

Autoimmune thyroiditis in patients with sudden sensorineural hearing loss

Laryngoscope Investigative Otolaryngology, 2022
Objective This study aims to evaluate the association between autoimmune thyroiditis and Sudden Sensorineural Hearing Loss (SSNHL). Methods Hundred and five patients with SSNHL were enrolled.
Xiao‐Mei Sun, Shi‐Min Zhuang, Zhi‐Wen Xiao, Jia‐Qi Luo, Zhen Long, Lin‐Chan Lan, Hui‐Qing Zhang, Guan‐Ping Zhang   +7 more
doaj   +1 more source

Elevated levels of interleukin-9 in the serum of bullous pemphigoid: possible association with the pathogenicity of bullous pemphigoid

Frontiers in Immunology, 2023
Bullous pemphigoid (BP) is an autoimmune subepidermal blistering disease (sAIBD). In addition to disease causing autoantibodies, several leukocyte subsets, including mast cells and eosinophils, play key roles in mediating skin inflammation.
Hiroshi Koga, Kwesi Teye, Arisa Sugawara, Masahiro Tsutsumi, Norito Ishii, Takekuni Nakama   +5 more
doaj   +1 more source

Baseline autoantibody profile in rheumatoid arthritis is associated with early treatment response but not long-term outcomes

Arthritis Research & Therapy, 2018
Background The autoantibody profile of seropositive rheumatoid arthritis (RA) is very diverse and consists of various isotypes and antibodies to multiple post-translational modifications. It is yet unknown whether this varying breadth of the autoantibody
Emma C. de Moel, Veerle F. A. M. Derksen, Gerrie Stoeken, Leendert A. Trouw, Holger Bang, Robbert J. Goekoop, Irene Speyer, Tom W. J. Huizinga, Cornelia F. Allaart, René E. M. Toes, Diane van der Woude   +10 more
doaj   +1 more source

A Genetic Risk Score Distinguishes Different Types of Autoantibody-Mediated Membranous Nephropathy

Glomerular Diseases, 2023
Introduction: Membranous nephropathy (MN) is the leading cause of nephrotic syndrome in adults and is characterized by detectable autoantibodies against glomerular antigens, most commonly phospholipase A2 receptor 1 (PLA2R1) and thrombospondin type-1 ...
Sanjana Gupta, Mallory Louise Downie, Chris Cheshire, Stephanie Dufek-Kamperis, Adam Paul Levine, Paul Brenchley, Elion Hoxha, Rolf Stahl, Neil Ashman, Ruth Jennifer Pepper, Sean Mason, Jill Norman, Detlef Bockenhauer, Horia Constantin Stanescu, Robert Kleta, Daniel Philip Gale   +15 more
doaj   +1 more source

Anti-BIRC5 autoantibody serves as a valuable biomarker for diagnosing AFP-negative hepatocellular carcinoma [PDF]

PeerJ
Background Autoantibodies targeting tumor-associated antigens (TAAbs) have emerged as promising biomarkers for early cancer detection. This research aimed to assess the diagnostic capacity of anti-BIRC5 autoantibody in detecting AFP-negative ...
Qing Li, Haiyan Liu, Han Wang, Wenzhuo Xiong, Liping Dai, Xiuzhi Zhang, Peng Wang, Hua Ye, Jianxiang Shi, Zhihao Fang, Keyan Wang   +10 more
doaj   +2 more sources

Advancing Luciferase-Based Antibody Immunoassays to Next-Generation Mix and Read Testing

Biosensors, 2023
Antibody measurements play a central role in the diagnosis of many autoimmune and infectious diseases. One antibody detection technology, Luciferase Immunoprecipitation Systems (LIPS), utilizes genetically encoded recombinant luciferase antigen fusion ...
Peter D. Burbelo, Youngmi Ji, Michael J. Iadarola   +2 more
doaj   +1 more source

Islet autoantibodies as precision diagnostic tools to characterize heterogeneity in type 1 diabetes: a systematic review

Communications Medicine
Background Islet autoantibodies form the foundation for type 1 diabetes (T1D) diagnosis and staging, but heterogeneity exists in T1D development and presentation.
Jamie L. Felton, Maria J. Redondo, Richard A. Oram, Cate Speake, S. Alice Long, Suna Onengut-Gumuscu, Stephen S. Rich, Gabriela S. F. Monaco, Arianna Harris-Kawano, Dianna Perez, Zeb Saeed, Benjamin Hoag, Rashmi Jain, Carmella Evans-Molina, Linda A. DiMeglio, Heba M. Ismail, Dana Dabelea, Randi K. Johnson, Marzhan Urazbayeva, John M. Wentworth, Kurt J. Griffin, Emily K. Sims, On behalf of the ADA/EASD PMDI   +22 more
doaj   +1 more source

Autoantigen Microarray for High-throughput Autoantibody Profiling in Systemic Lupus Erythematosus

Genomics, Proteomics & Bioinformatics, 2015
Systemic lupus erythematosus (SLE) is a complex autoimmune disease characterized by the production of autoantibodies to a broad range of self-antigens. Profiling the autoantibody repertoire using array-based technology has emerged as a powerful tool for ...
Honglin Zhu, Hui Luo, Mei Yan, Xiaoxia Zuo, Quan-Zhen Li   +4 more
doaj   +1 more source

Use of thymidine kinase 1 autoantibody, thymidine kinase antigen, extracellular protein kinase A autoantibody, and C‐reactive protein for early detection of malignant tumors in dogs

Journal of Veterinary Internal Medicine
Background Although the importance of early diagnosis of malignant tumors is a major concern, an easily accessible in‐house method has not been established.
Yoonhee Kim, Wonhee Lee, Byunggak Kim, Bonghwan Jang, Kyung‐Rok Yu, Hong Sook Kim, Minok Ryu, Yein Oh, Kyoungwon Seo, Chul Park, Ulsoo Choi, Dongha Bhang, Hwayoung Youn   +12 more
doaj   +1 more source

Identification of Novel Autoantibodies Based on the Human Proteomic Chips and Evaluation of Their Performance in the Detection of Gastric Cancer

Frontiers in Oncology, 2021
Autoantibodies against tumor-associated antigens (TAAbs) can be used as potential biomarkers in the detection of cancer. Our study aims to identify novel TAAbs for gastric cancer (GC) based on human proteomic chips and construct a diagnostic model to ...
Chi Cui, Chi Cui, Yaru Duan, Yaru Duan, Cuipeng Qiu, Cuipeng Qiu, Peng Wang, Peng Wang, Peng Wang, Guiying Sun, Guiying Sun, Hua Ye, Hua Ye, Hua Ye, Liping Dai, Liping Dai, Liping Dai, Zhuo Han, Zhuo Han, Chunhua Song, Chunhua Song, Kaijuan Wang, Kaijuan Wang, Jianxiang Shi, Jianxiang Shi, Jianxiang Shi, Jianxiang Shi, Jianying Zhang, Jianying Zhang, Jianying Zhang, Jianying Zhang   +30 more
doaj   +1 more source