Results 11 to 20 of about 228,187 (396)
PLoS Medicine, 2020 BackgroundBased on different genetic and environmental risk factors and histology, it has been proposed that rheumatoid arthritis (RA) consists of 2 types: autoantibody-positive and autoantibody-negative RA. However, until now, this remained hypothetical.
Xanthe M E Matthijssen +3 more
doaj +2 more sources
Positive Predictive Value of Myelin Oligodendrocyte Glycoprotein Autoantibody Testing
JAMA Neurology, 2021 Key Points Question What is the positive predictive value of myelin oligodendrocyte glycoprotein (MOG)–IgG1 testing in a clinical setting? Findings Of 1260 consecutive patients tested for MOG-IgG1 at the Mayo Clinic over 2 years, 92 (7.3%) were positive,
E. Sechi +13 more
semanticscholar +1 more source
Autoantibody-Specific Signalling in Pemphigus
Frontiers in Medicine, 2021 Pemphigus is a severe autoimmune disease impairing barrier functions of epidermis and mucosa. Autoantibodies primarily target the desmosomal adhesion molecules desmoglein (Dsg) 1 and Dsg 3 and induce loss of desmosomal adhesion.
T. Schmitt, J. Waschke
semanticscholar +1 more source
Use of thymidine kinase 1 autoantibody, thymidine kinase antigen, extracellular protein kinase A autoantibody, and C-reactive protein for early detection of malignant tumors in dogs. [PDF]
J Vet Intern MedBackground Although the importance of early diagnosis of malignant tumors is a major concern, an easily accessible in‐house method has not been established.
Kim Y +12 more
europepmc +2 more sources
Anti-Myxovirus Resistance Protein-1 Immunoglobulin A Autoantibody in Idiopathic Pulmonary Fibrosis
Canadian Respiratory Journal, 2022 Background. We have previously analysed serum autoantibody levels in patients with idiopathic pulmonary fibrosis (IPF), idiopathic nonspecific interstitial pneumonia (iNSIP), and healthy controls and identified the autoantibody against anti-myxovirus ...
Toru Arai +7 more
doaj +1 more source
BMC Pulmonary Medicine, 2021 Background Pirfenidone is an anti-fibrotic agent shown to slow the progression of idiopathic pulmonary fibrosis (IPF). However, its effectiveness in association with serological autoimmune features in IPF remains unclear.
Myung Jin Song +7 more
doaj +1 more source
Frontiers in Immunology, 2023 Comprehensive autoantibody evaluation is essential for the management of autoimmune disorders. However, conventional methods suffer from poor sensitivity, low throughput, or limited availability.
Ai Kuzumi +19 more
doaj +1 more source
A Mathematical Model of Thyroid Disease Response to Radiotherapy [PDF]
Mathematics 2021, 9(19), 2365, 2021 We present a mechanistic biomathematical model of molecular radiotherapy of thyroid disease. The general model consists of a set of differential equations describing the dynamics of different populations of thyroid cells with varying degrees of damage caused by radiotherapy (undamaged cells, sub-lethally damaged cells, doomed cells, and dead cells), as
arxiv +1 more source
Frontiers in Immunology, 2020 Myasthenia gravis (MG) is an autoimmune disease characterized by muscle weakness and fatiguability of skeletal muscles. It is an antibody-mediated disease, caused by autoantibodies targeting neuromuscular junction proteins.
K. Lazaridis, S. Tzartos
semanticscholar +1 more source
First-emerging islet autoantibody and glucose metabolism: search for type 1 diabetes subtypes
Endocrine Connections, 2022 Objective: Subtypes in type 1 diabetes pathogenesis have been implicated based on the first-appearing autoantibody (primary autoantibody). We set out to describe the glucose metabolism in preclinical diabetes in relation to the primary autoantibody in ...
Olli Helminen +6 more
doaj +1 more source