Autoantibodies against retinal proteins in paraneoplastic and autoimmune retinopathy [PDF]
, 2004 BACKGROUND: Autoimmune retinal degeneration may occur in patients who present with sudden or, less commonly, subacute loss of vision of retinal origin, associated with an abnormal ERG, through the action of autoantibodies against retinal proteins.
AH Milam +31 more
core +3 more sources
Different Hierarchies of Anti–Modified Protein Autoantibody Reactivities in Rheumatoid Arthritis
Arthritis & Rheumatology, 2020 Anti–citrullinated protein antibodies (ACPAs) are a hallmark of seropositive rheumatoid arthritis (RA). Yet, the precise disease‐relevant autoantigens that are targeted by ACPAs remains a matter of debate.
P. Sahlström +15 more
semanticscholar +1 more source
Biomedicines, 2022 The aim of this study was to explore the value of autoantibody to GNAS in the early detection of hepatocellular carcinoma (HCC). In a large-scale sample set of 912 participants (228 cases in each of HCC, liver cirrhosis (LC), chronic hepatitis B (CHB ...
Xiao Wang +7 more
doaj +1 more source
Screening for type 1 diabetes-, thyroid-, gastric-, and adrenal-specific humoral autoimmunity in 529 children and adolescents with celiac disease at diagnosis identifies as positive one in every nine patients [PDF]
, 2016 No abstract ...
Anania, Caterina +9 more
core +1 more source
Predominant Autoantibody Production by Early Human B Cell Precursors
Science, 2003 During B lymphocyte development, antibodies are assembled by random gene segment reassortment to produce a vast number of specificities. A potential disadvantage of this process is that some of the antibodies produced are self-reactive. We determined the
H. Wardemann +5 more
semanticscholar +1 more source
Diabetes Care, 2020 OBJECTIVE The first-appearing β-cell autoantibody has been shown to influence risk of type 1 diabetes (T1D). Here, we assessed the risk of autoantibody spreading to the second-appearing autoantibody and further progression to clinical disease in The ...
Kendra Vehik +12 more
semanticscholar +1 more source
Does diabetes appear in distinct phenotypes in young people? Results of the diabetes mellitus incidence Cohort Registry (DiMelli). [PDF]
PLoS ONE, 2013 INTRODUCTION: The diabetes mellitus Incidence Cohort Registry (DiMelli) aims to characterize diabetes phenotypes by immunologic, metabolic, and genetic markers.
Katharina Warncke +5 more
doaj +1 more source
Can unilateral, progressive or sudden hearing loss be immune-mediated in origin? [PDF]
, 2017 OBJECTIVE: The aim of the present study was to demonstrate that the positivity of nonspecific immunological tests could be found not only in bilateral hearing loss but also in unilateral cases, either sudden or progressive. METHOD: An observational case
Atturo, Francesca +4 more
core +1 more source
Prevalence and reactivity of anti-melanoma differentiation-associated gene 5 (anti-MDA-5) autoantibody in Brazilian patients with dermatomyositis [PDF]
Anais Brasileiros de Dermatologia, 2018 : Background: There have been no studies to date on the frequency and reactivity of aanti-melanoma differentiation-associated gene 5 (anti-MDA-5) in samples from the Brazilian population with dermatomyositis. Objectives: To analyze this autoantibody in
Isabela Bruna Pires Borges +2 more
doaj +1 more source
Autoantibody Discovery, Assay Development and Adoption: Death Valley, the Sea of Survival and Beyond
Frontiers in Immunology, 2021 Dating to the discovery of the Lupus Erythematosus (LE) cell in 1948, there has been a dramatic growth in the discovery of unique autoantibodies and their cognate targets, all of which has led to the availability and use of autoantibody testing for a ...
Marvin J. Fritzler +3 more
doaj +1 more source