Results 31 to 40 of about 132,341 (349)

Prevalence and Outcome of Serum Autoantibodies in Chronic Hepatitis C Patients Undergoing Direct-Acting Antiviral Treatment

open access: yesFrontiers in Immunology, 2022
BackgroundChronic immune stimulation by hepatitis C virus (HCV) may cause occurrence of several autoantibodies in infected patients, with or without features of clinically overt autoimmune diseases.
Ciro Romano   +6 more
doaj   +1 more source

Mesenchymal stem cells: A novel treatment option for primary sclerosing cholangitis

open access: yesCell Biology International, Volume 47, Issue 2, Page 467-479, February 2023., 2023
Abstract Primary sclerosing cholangitis (PSC) is a progressive liver disease for which there is no effective therapy. Hepatocytes and cholangiocytes from a PSC patient were cocultured with mesenchymal stem cells (MSCs) to assess in vitro change. A single patient with progressive PSC was treated with 150 million MSCs via direct injection into the common
Amy L. Lightner   +8 more
wiley   +1 more source

Systemic translocation of Staphylococcus drives autoantibody production in HIV disease

open access: yesMicrobiome, 2019
Background Increased autoreactive antibodies have been reported in HIV disease; however, the mechanism accounting for autoantibody induction in HIV remains unknown.
Zhenwu Luo   +21 more
doaj   +1 more source

Autoreactive B cells recruited to lungs by silica exposure contribute to local autoantibody production in autoimmune-prone BXSB and B cell receptor transgenic mice

open access: yesFrontiers in Immunology, 2022
Occupational exposure to inhaled crystalline silica dust (cSiO2) is linked to systemic lupus erythematosus, rheumatoid arthritis, systemic sclerosis, and anti-neutrophil cytoplasmic autoantibody vasculitis.
Lanette Fee   +6 more
doaj   +1 more source

Autoimmune thyroiditis in patients with sudden sensorineural hearing loss

open access: yesLaryngoscope Investigative Otolaryngology, 2022
Objective This study aims to evaluate the association between autoimmune thyroiditis and Sudden Sensorineural Hearing Loss (SSNHL). Methods Hundred and five patients with SSNHL were enrolled.
Xiao‐Mei Sun   +7 more
doaj   +1 more source

Expression-Based Genome-Wide Association Study Links Vitamin D-Binding Protein With Autoantigenicity in Type 1 Diabetes. [PDF]

open access: yes, 2016
Type 1 diabetes (T1D) is caused by autoreactive T cells that recognize pancreatic islet antigens and destroy insulin-producing β-cells. This attack results from a breakdown in tolerance for self-antigens, which is controlled by ectopic antigen expression
Butte, Atul J   +9 more
core   +1 more source

S100a9 Protects Male Lupus-Prone NZBWF1 Mice From Disease Development

open access: yesFrontiers in Immunology, 2021
Systemic lupus erythematosus (SLE) is an autoimmune disorder disproportionally affecting women. A similar sex difference exists in the murine New Zealand Black/White hybrid model (NZBWF1) of SLE with all females, but only 30-40% of males, developing ...
Laura M. Davison   +11 more
doaj   +1 more source

Influence of peptidylarginine deiminase type 4 genotype and shared epitope on clinical characteristics and autoantibody profile of rheumatoid arthritis. [PDF]

open access: yes, 2009
Background: Recent evidence suggests that distinction of subsets of rheumatoid arthritis (RA) depending on anticyclic citrullinated peptide antibody (anti-CCP) status may be helpful in distinguishing distinct aetiopathologies and in predicting the ...
Burmester, G.R.   +7 more
core   +1 more source

Evaluation of sweating responses in patients with systemic connective tissue disorders using the quantitative sudomotor axon reflex test

open access: yesJournal of Cutaneous Immunology and Allergy, Volume 5, Issue 6, Page 208-216, December 2022., 2022
We investigated 85 patients on the relationship between the axon reflex sweat volume or the reaction time and Raynaud's phenomenon, skin symptoms and patient background. Most patients did not show a decrease in sweating, but one in three patients showed less sweating in summer than in winter.
Miwa Ashida   +5 more
wiley   +1 more source

Autoreactivity to malondialdehyde-modifications in rheumatoid arthritis is linked to disease activity and synovial pathogenesis [PDF]

open access: yesJ Autoimmun. 2017 Nov; 84:29-45, 2017
Oxidation-associated malondialdehyde (MDA) modification of proteins can generate immunogenic neo-epitopes that are recognized by autoantibodies. In health, IgM antibodies to MDA-adducts are part of the natural antibody pool, while elevated levels of IgG anti-MDA are associated with inflammatory conditions.
arxiv   +1 more source

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