Results 101 to 110 of about 59,330 (297)

Peripheral blood biomarkers in multiple sclerosis. [PDF]

, 2015
Multiple sclerosis is the most common autoimmune disorder affecting the central nervous system. The heteroge-neity of pathophysiological processes in MS contributes to the highly variable course of the disease and unpre-dictable response to therapies ...
Acheson, Achiron, Ada Francia, Agmon-Levin, Aktas, Alatab, Alexander, Amorini, Anderson, Antonella D'Ambrosio, Arbour, Arnson, Arrambide, Ascherio, Ascherio, Ascherio, Axtell, Bar-Or, Barkhof, Barkhof, Barteneva, Bartosik-Psujek, Berger, Bertolotto, Bertolotto, Bertolotto, Bianco, Bielekova, Biomarkers Definitions Working Group, Bittner, Bloomgren, Braun, Brettschneider, Brex, Browne, Burger, Bustamante, Bustamante, Buttmann, Buzas, Bălaşa, Cantorna, Carotenuto, Carson, Cermelli, Chabas, Chen, Ciusani, Clifford, Cocucci, Colombo, Comabella, Comabella, Comabella, Comabella, Comi, Confavreux, Correale, Corvol, Cox, Creeke, D'Aurizio, D'Souza, Dalmau, De Jager, De Jager, De Santis, Deisenhammer, Derfuss, Dhib-Jalbut, Distler, Doyle, Du, Egg, Ehling, Eikelenboom, Engelhardt, Esteller, Eulalio, Fabriek, Farrell, Fenoglio, Fialová, Fissolo, Fonalledas Perelló, Fox, Freedman, Friedman, Galboiz, Gandhi, Gao, Ge, Gianchecchi, Gilli, Gilli, Giovannoni, Goldberg, Goodin, Graber, Graber, Gresle, Gresle, Guo, Haak, Haller, Hanke, Harris, Hartung, Hayes, Hecker, Hecker, Hellerqvist, Hinson, Horstman, Huang, Huang, Hur, Inoue, Ioannidis, Jimenez, Johnson, Julien, Junker, Kacperska, Kallaur, Kamath, Kasper, Kayagaki, Keller, Kemppinen, Knox, Korn, Korteweg, Kuenz, Kuhle, Kurtzke, Kvistad, Kwon, Lai, Lalive, Laroni, Lassmann, Lassmann, Lau, Lemire, Leppert, Leray, Lewis, Liang, Lily, Lin, Lindberg, Linington, Liotta, Littman, Liu, Lolli, Lopatinskaya, Lopatinskaya, Losseff, Losseff, Losy, Lovett-Racke, Lowery-Nordberg, Lublin, Lublin, Lucchinetti, Lycke, Lünemann, Lünemann, Major, Malucchi, Marchi, Markiewicz, Markovic-Plese, Martinelli-Boneschi, Marzesco, Masuoka, Mayer, Mazzali, McDonald, Miller, Minagar, Minagar, Minagar, Minagar, Missler, Mitchell, Momen-Heravi, Morel, Moreno, Mowry, Munger, Muralidharan-Chari, Murugaiyan, Myers, Nelissen, Nelissen, Norling, O'Connell, O'Connell, Oliveira, Oliver, Opdenakker, Opsahl, Otaegui, Pachner, Pachner, Pachner, Paola Margutti, Papini, Park, Pawate, Pelajo, Pender, Petereit, Peterson, Petrocca, Poloni, Probstel, Qin, Qu, Quintana, Redell, Reder, Reindl, Reindl, Rieckmann, Rieder, Riverol, Romo-Tena, Rovaris, Rudick, Rudick, Rudick, Sadiq, Salama, Sato, Schwarz, Schwarz, Selmi, Semra, Sendid, Sharief, Sharief, Sharief, Sharief, Shaw, Sheremata, Sievers, Silber, Silvia Zamboni, Siman, Simona Pontecorvo, Simpson, Soldan, Soldan, Sospedra, Srivastava, Stewart, Stüve, Sundström, Sáenz-Cuesta, Sáenz-Cuesta, Tania Colasanti, Tao, Teunissen, Tintoré, Trabattoni, Trampe, Turiák, van Horssen, Varga, Vartanian, Verderio, Villoslada, Virtanen, Vogt, Vogt, Wandinger, Wang, Waschbisch, Waubant, Waubant, Waubant, Waubant, Weinstock-Guttman, Wekerle, Xiao, Yong, Yong, Yousry, Zahednasab, Zang, Zhang, Zhu, Zipp, Zisimopoulou, Zula   +298 more
core   +1 more source

Potential roles of antibodies with different classes in IgG4‐related diseases

Rheumatology &Autoimmunity, EarlyView.
This review discussed the common characteristics of different classes of antibodies and their potential corresponding unique mechanisms involved in immunoglobulin G4‐related disease. Abstract Immunoglobulin G4‐related disease (IgG4‐RD), first identified two decades ago, is an immune‐mediated pro‐inflammatory and profibrotic disease entity affecting ...
Ling Li, Shaozhe Cai, Shengyan Lin, Lin Bai, Zhihua Yu, Wei Sun, Lingli Dong   +6 more
wiley   +1 more source

The nature of the post-translational modifications of the autoantigen LL37 influences the autoreactive T-helper cell phenotype in psoriasis

Frontiers in Immunology
Psoriasis is a chronic skin disease evolving to psoriatic arthritis (PsA) in 30% of cases. LL37 is a psoriasis T-cell autoantigen and, in complex with self-DNA/RNA, a trigger of type I interferon (IFN-I) and pro-inflammatory factors in dendritic cells ...
Roberto Lande, Anna Mennella, Raffaella Palazzo, Rebecca Favaro, Rebecca Favaro, Paola Facheris, Flavia Mancini, Giuseppe Ocone, Elisabetta Botti, Mario Falchi, Immacolata Pietraforte, Curdin Conrad, Luca Bianchi, Antonio Costanzo, Antonio Costanzo, Loredana Frasca   +15 more
doaj   +1 more source

Post-translational modifications, subcellular relocation and release in apoptotic microparticles: apoptosis turns nuclear proteins into autoantigens.

Folia Histochemica et Cytobiologica, 2010
Autoantibodies against particular nuclear components, such as chromatin and snRNPs, are a characteristic feature of the autoimmune disease systemic lupus erythematosus.
Sylviane Muller, JĂźrgen Dieker
doaj   +1 more source

RNA-associated autoantigens activate B cells by combined B cell antigen receptor/Toll-like receptor 7 engagement

Journal of Experimental Medicine, 2005
Previous studies (Leadbetter, E.A., I.R. Rifkin, A.H. Hohlbaum, B. Beaudette, M.J. Shlomchik, and A. Marshak-Rothstein. 2002. Nature. 416:603–607; Viglianti, G.A., C.M. Lau, T.M. Hanley, B.A. Miko, M.J. Shlomchik, and A. Marshak-Rothstein. 2003. Immunity.
Christina M. Lau, C. Broughton, Abigail S. Tabor, S. Akira, R. Flavell, M. Mamula, S. Christensen, M. Shlomchik, G. Viglianti, I. Rifkin, A. Marshak‐Rothstein   +10 more
semanticscholar   +1 more source

An Epigenetics-Based Hypothesis of Autoantigen Development in Systemic Lupus Erythematosus

Epigenomes, 2020
Currently, we have a limited understanding of mechanisms leading to systemic lupus erythematosus, but we know that genetics, environmental factors, and epigenetics contribute to the disease. One common aspect of the various environmental triggers is that
Wesley Brooks
doaj   +1 more source

Exploring Morphology of Thermoplasmonic Nanoparticles to Synergize Immunotherapeutic Fibroblast Activation Protein‐Positive Cell Sensitization and Photothermal Therapy

Small Science, EarlyView.
Schematic of spherical and branched gold nanoparticle‐based nanocarriers conjugated with targeting modules (TMs), previously designed for chimeric antigen receptor T‐cell (CAR T‐cell) recognition of fibroblast activation protein (FAP). By combining immunotherapeutic TMs with thermoplasmonic AuNPs, these nanoconjugates selectively sensitize FAP ...
Ahmed Alsadig, Xuan Peng, Hugo Boutier, Liliana R. Loureiro, Anja Feldmann, René Hübner, Humberto Cabrera, Manja Kubeil, Michael Bachmann, Larysa Baraban   +9 more
wiley   +1 more source

Treatment options for immune‐related adverse events associated with immune checkpoint inhibitors

British Journal of Pharmacology, EarlyView.
Abstract The immunotherapy revolution with the use of immune checkpoint inhibitors (ICIs) started with the clinical use of the first ICI, ipilimumab, in 2011. Since then, the field of ICI therapy has rapidly expanded — with the FDA approval of 10 different ICI drugs so far and their incorporation into the therapeutic regimens of a range of malignancies.
Yu Hua Chen, Tamás Kovács, Péter Ferdinandy, Zoltán V. Varga   +3 more
wiley   +1 more source

A repertoire of 124 potential autoantigens for autoimmune kidney diseases identified by dermatan sulfate affinity enrichment of kidney tissue proteins.

PLoS ONE, 2019
Autoantigens are the molecular targets in autoimmune diseases. They are a cohort of seemingly unrelated self-molecules present in different parts of the body, yet they can trigger a similar chain of autoimmune responses such as autoantibody production ...
Wei Zhang, Jung-Hyun Rho, Michael W Roehrl, Michael H Roehrl, Julia Y Wang   +4 more
doaj   +1 more source

Posttranslational Modification of HLA-DQ Binding Islet Autoantigens in Type 1 Diabetes

Diabetes, 2013
Posttranslational modification (PTM) of islet autoantigens can cause lack of central tolerance in type 1 diabetes (T1D). Tissue transglutaminase (tTG), involved in PTM of gluten antigens in celiac disease, creates negatively charged peptides favored by ...
M. van Lummel, G. Duinkerken, P. V. van Veelen, Arnoud H. de Ru, R. Cordfunke, A. Zaldumbide, I. Gomez-Tourino, S. Arif, M. Peakman, J. Drijfhout, B. Roep   +10 more
semanticscholar   +1 more source