Results 121 to 130 of about 44,843 (259)
Autoimmunity and Periodontitis
Journal of Periodontal Research, EarlyView.In a microbe‐driven inflammatory environment, peptidyl‐arginine deiminase (PAD) enzymes from neutrophils and Porphyromonas gingivalis citrullinate both microbial and self‐antigens. B cell presentation of citrullinated or self‐mimicking epitopes activates T cells that assist B cells in antibody isotype switching, affinity maturation, epitope spreading ...
Massimo Costalonga +2 more
wiley +1 more source
ファージディスプレイ法による自己免疫疾患の自己抗原の探索 [PDF]
, 2018 筑波大学 (University of Tsukuba ...
Niwa Mikio, 丹羽 幹夫
core +2 more sources
Periodontal Medicine Rewired: Mechanisms Linking Periodontitis to Systemic Diseases
Journal of Periodontal Research, EarlyView.This review reorganizes decades of research in periodontal medicine into a multi‐dimensional framework, illustrating how periodontitis influences systemic health through at least seven interconnected mechanisms. ABSTRACT Periodontitis is now recognized not merely as a localized oral condition but as a systemic disease linked to over 70 communicable and
Mario Romandini +3 more
wiley +1 more source
Systemic Disease Associations of Oral Lichenoid Disease: A Retrospective Case–Control Study
Oral Diseases, EarlyView.ABSTRACT Objective To analyze the association between oral lichen planus (OLP), oral lichenoid lesions (OLL), and other comorbidities. Material and Methods A case–control study of 205 OLP, 96 OLL patients, and 301 age‐ and sex‐matched controls from Kuopio University Hospital was performed.
Mari Vehviläinen +3 more
wiley +1 more source
Oral Microbiome in Systemic Autoimmune Diseases: A Systematic Review
Oral Diseases, EarlyView.ABSTRACT Objective The oral cavity represents a key but underexplored interface between host immunity and microbial communities. The aim of this systematic review was to synthesize current literature on oral microbiota alterations in systemic autoimmune diseases.
Sophie Jung +2 more
wiley +1 more source
Tumorigenesis as an autoimmune process
Медицинская иммунологияThe data presented in the article reasonably indicate that the immune system responses during the development of autoimmune pathology and in the process of tumor growth are, in fact, autoimmune responses directed at autoantigens of various tissues and ...
V. A. Kozlov
doaj +1 more source
Citation: 'autoantigen' in the IUPAC Compendium of Chemical Terminology, 5th ed.; International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.12914 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire +1 more source
Periodontitis and rheumatoid arthritis—Global efforts to untangle two complex diseases
Periodontology 2000, EarlyView.Abstract Understanding the impact of oral health on rheumatoid arthritis (RA) will inform how best to manage patients with both periodontitis and RA. This review seeks to provide an update on interventional and mechanistic investigations, including a brief summary of European Research programs investigating the link between periodontitis and RA. Recent
Isabel Lopez‐Oliva +2 more
wiley +1 more source
CAR‐T Cells in Ulcerative Colitis: The Renaissance of B‐Cell Targeted Therapy in UC
JCC Plus, Volume 1, Issue 4, July 2026.ABSTRACT A recent New England Journal of Medicine report described the first successful use of anti‐CD19 CAR‐T cell therapy in a patient with multirefractory ulcerative colitis (UC). This exceptional case provides striking proof of concept that B cells and plasma cells can act as key pathogenic drivers in UC.
Zlata Chkolnaia +2 more
wiley +1 more source
Thymus and Leishmania at the Crossroads: Autoimmunity and Cancer
Immunology, Volume 178, Issue 3, Page 377-386, July 2026.Conceptual ‘Crossroads Model’ linking Leishmania, thymic infection and immune dysregulation: an integrative model is proposed in which Leishmania infection disrupts thymic architecture and stromal–thymocyte interactions. These alterations converge to promote defective tolerance, increased autoimmune risk and a microenvironment permissive to malignant ...
Alef Batista Bezerra Barros +5 more
wiley +1 more source