Salivary and lacrimal gland involvement is a characteristic feature of primary Sjögren’s syndrome (pSS), where tissue destruction is mediated by mononuclear cell infiltration, resulting in lacrimal and salivary gland impairment.
Kathrine Skarstein+5 more
doaj +1 more source
Dilated cardiomyopathy (DCM) is a myocardial disease characterized by progressive depression of myocardial contractile function and ventricular dilatation.
Cahill, D.+10 more
core +1 more source
Purification and partial sequencing of the nuclear autoantigen RA33 shows that it is indistinguishable from the A2 protein of the heterogeneous nuclear ribonucleoprotein complex. [PDF]
G Steiner+8 more
openalex +1 more source
The gut microbiome associated with LGI1‐antibody encephalitis
Abstract Objective Autoimmune encephalitis is a cause of brain inflammation characterized by auto‐antibodies, which target cell surface neuronal proteins and lead to neuronal dysfunction. The most common form is associated with auto‐antibodies to leucine‐rich glioma‐inactivated 1 (LGI1) protein, the presentation of which includes frequent focal ...
Edmund Gilbert+12 more
wiley +1 more source
Isolation of a 330-kDa glycoprotein from human kidney similar to the Heymann nephritis autoantigen (gp330). [PDF]
John J. Kanalas, S. P. Makker
openalex +1 more source
ABSTRACT Aim Primary biliary cholangitis (PBC) is an autoimmune liver disease marked by progressive bile duct damage, leading to bile retention. Dendritic cells (DCs), as antigen‐presenting cells, are crucial for immune regulation, and their dysfunction is linked to autoimmunity.
Jiaqi Zhang+6 more
wiley +1 more source
Ku autoantigen is the regulatory component of a template-associated protein kinase that phosphorylates RNA polymerase II. [PDF]
Arik Dvir+4 more
openalex +1 more source
A case of visceral leishmaniasis mimicking connective tissue disease
Rheumatology &Autoimmunity, EarlyView.
Yucui Li+4 more
wiley +1 more source
PD‐1 expressing islet‐specific CD4+ T cells promote bystander tolerance and prevent autoimmunity
We investigated the requirement for programmed death 1 (PD‐1) expression by CD4+ T cells in the maintenance of self‐tolerance via bystander suppression of autoreactive CD8+ T cells. Using CRISPR/Cas9 to selectively knockout PD‐1 in islet antigen‐specific BDC2.5 CD4+ T cells, we demonstrate that loss of PD‐1 promoted the proliferation, Th1‐like effector‐
Jeniffer D Loaiza Naranjo+5 more
wiley +1 more source
Localization of human platelet autoantigens to the cysteine-rich region of glycoprotein IIIa. [PDF]
Riitta Kekomäki+3 more
openalex +1 more source