Results 11 to 20 of about 48,629 (258)

B‐cell receptors of EBV‐negative Burkitt lymphoma bind modified isoforms of autoantigens

open access: yeseJHaem, 2022
Burkitt lymphoma (BL) represents the most aggressive B‐cell‐lymphoma. Beside the hallmark of IG‐MYC‐translocation, surface B‐cell receptor (BCR) is expressed, and mutations in the BCR pathway are frequent.
Theresa Bock   +24 more
doaj   +1 more source

The relationship between chronic immune response and neurodegenerative damage in long COVID-19

open access: yesFrontiers in Immunology, 2022
In the past two years, the world has faced the pandemic caused by the severe acute respiratory syndrome 2 coronavirus (SARS-CoV-2), which by August of 2022 has infected around 619 million people and caused the death of 6.55 million individuals globally ...
José Pedro Elizalde-Díaz   +3 more
doaj   +1 more source

Anti-Idiotypic mRNA Vaccine to Treat Autoimmune Disorders

open access: yesVaccines, 2023
The 80+ existing autoimmune disorders (ADs) affect billions with little prevention or treatment options, except for temporary symptomatic management, leading to enormous human suffering and a monumental financial burden. The autoantibodies formed in most
Sarfaraz K. Niazi
doaj   +1 more source

Equine recurrent uveitis - A spontaneous horse model of uveitis [PDF]

open access: yes, 2008
Equine recurrent uveitis (ERU) is an autoimmune disease that occurs with a high prevalence (10%) in horses. ERU represents the only reliable spontaneous model for human autoimmune uveitis.
Altmann, Frank   +8 more
core   +1 more source

A rare entity: Sympathetic ophthalmia presumably after blunt trauma to the phthisical eye and optical coherence tomography angiography metrics to monitor response to treatment

open access: yesClinical Case Reports, 2020
A blunt trauma to a phthisical eye may elicit sympathetic ophthalmia. Non invasive imaging such as use of optical coherence tomography and angiography metrics of the retinal and choroidal vasculature can help monitor response to the treatment.
Anadi Khatri   +6 more
doaj   +1 more source

Neutrophils: An Important Player in Systemic Lupus Erythematosus [PDF]

open access: yesJournal of Clinical and Diagnostic Research
The immune system contains several different cells that act as the first line of defence, reacting to a broad range of intruders as quickly as possible; an example of such cells is neutrophils. There has been increased focus on neutrophils due to the key
Nuha A Alkhattabi
doaj   +1 more source

Immunoregulatory soluble CTLA-4 modifies effector T cell responses in systemic lupus erythematosus [PDF]

open access: yes, 2016
Acknowledgments This work was supported by Arthritis Research UK (Grant no. 19282). We are grateful to Dr. Nick Fluck for his invaluable support in recruiting patients for the study, and Mrs.
Barker, Robert N.   +6 more
core   +3 more sources

Immune System, Inflammation and Autoantigens in Wet Age-Related Macular Degeneration: Pathological Significance and Therapeutic Importance

open access: yesLife, 2023
Wet age-related macular degeneration (wAMD) is a chronic inflammation-associated neurodegenerative disease affecting the posterior part of the eye in the aging population.
Sreeraj Kuruppilakath Manikandan   +6 more
doaj   +1 more source

Expression-Based Genome-Wide Association Study Links Vitamin D-Binding Protein With Autoantigenicity in Type 1 Diabetes. [PDF]

open access: yes, 2016
Type 1 diabetes (T1D) is caused by autoreactive T cells that recognize pancreatic islet antigens and destroy insulin-producing β-cells. This attack results from a breakdown in tolerance for self-antigens, which is controlled by ectopic antigen expression
Butte, Atul J   +9 more
core   +1 more source

Neutrophil Extracellular Traps (NETs) Take the Central Stage in Driving Autoimmune Responses

open access: yesCells, 2020
Following fifteen years of research, neutrophil extracellular traps (NETs) are widely reported in a large range of inflammatory infectious and non-infectious diseases. Cumulating evidences from in vitro, in vivo and clinical diagnostics suggest that NETs
Esther Fousert, René Toes, Jyaysi Desai
doaj   +1 more source

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