Results 211 to 220 of about 49,748 (241)

Ubiquitination of Ro52 autoantigen

Biochemical and Biophysical Research Communications, 2002
Anti-Ro/SSA antibodies are antinuclear antibodies most commonly found in patients with Sjögren's syndrome, a chronic autoimmune disease characterized by dryness of the eyes and mouth. The autoantibodies recognize a RING-finger protein, Ro52/SSA (52 kDa), whose function is still unknown. In this study, the ubiquitination of Ro52 was investigated.
Taeko, Fukuda-Kamitani, Tetsu, Kamitani
openaire   +2 more sources

Thermostable Brain-Specific Autoantigen

The Journal of Immunology, 1967
Summary Evidence was presented for autoantibody formation against a thermostable ethanol-insoluble antigen (BE antigen) characteristic for brain. Rabbit antisera to brain BE of human and porcine origin combined with rabbit brain BE. Antisera of rabbits immunized with rabbit brain BE and of pigs immunized with porcine brain BE contained ...
F, Milgrom, Z M, Tuggac, W, Campbell, E, Witebsky   +3 more
openaire   +2 more sources

Golgi Autoantibodies and Autoantigens

Journal of Autoimmunity, 1994
Autoantibodies directed against cellular constituents rarely react with antigens localized in the Golgi apparatus and little information is available regarding these particular antibodies. Although thousands of samples have been examined for autoantibodies in our laboratory on a routine basis, only three human sera with anti-Golgi antibodies could be ...
G, Renier, M C, Rousselet, F, Carrere, A, Croue, C, André, F, Oksman, A, Chevailler, D, Hurez   +7 more
openaire   +2 more sources

Sperm autoantigens and fertilization. III. Ultrastructural localization of guinea pig autoantigens

The Anatomical Record, 1982
AbstractGuinea pig sperm autoantigens have been localized by direct and indirect immunoferritin techniques in (1) plasma membrane over the entire sperm head, (2) acrosomal contents, (3) fibrous sheath and outer dense fibers of the tail filament, and (4) the inner acrosomal membrane of 50% of acrosome reacted spermatozoa.
K S, Tung, H, Yanagimachi, R, Yanagimachi   +2 more
openaire   +2 more sources

Hepatic and biliary Autoantigens

Immunological Investigations, 1989
Chronic active hepatitis (CAH) and primary biliary cirrhosis (PBC) are two enigmatic liver diseases in which autoimmunity is implicated. Provisional criteria to separate the autoimmune type of CAH (A-CAH) from others are specified. Western immunoblotting using disease sera and antibody screening of a rat liver gene expression library were used to ...
openaire   +2 more sources

Autoantigens and Sjögren Syndrome

Cornea, 2002
To review recent experimental evidence on the involvement of autoantigens and autoantibodies in the pathogenesis of organ-specific autoimmunity in Sjögren syndrome (SS).Among candidate autoantigens in SS, we investigated the role of alpha-fodrin in the lacrimal gland using a mouse model and a lacrimal gland cell line established in p53 knockout mice ...
openaire   +2 more sources

Recombinant autoantigens.

Annals of the rheumatic diseases, 1990
Highly specific serum autoantibodies directed at cellular macromolecules are detectable in the serum of many patients with autoimmune connective tissue diseases. This phenomenon has been useful in diagnosis and in identifying disease subsets. The mechanism whereby the immune system selects these specific targets, and their relation to the events of ...
openaire   +1 more source

[Genes for autoantigens].

Nihon rinsho. Japanese journal of clinical medicine, 1999
Thyroid autoantigens have been well studied in view of the identification corresponding to respective autoantibodies in circulation, which are utilized as a diagnostic or follow-up marker of autoimmune thyroid diseases. There are several thyroid autoantigen genes cloned, such as thyroglobulin (TG), thyroid peroxidase (TPO), thyrotropin receptor (TSHR ...
N, Takamura, S, Yamashita
openaire   +1 more source

NATIVE AUTOANTIGENS VERSUS RECOMBINANT AUTOANTIGENS

2007
PATRICK S.C. LEUNG, M. ERIC GERSHWIN
openaire   +1 more source

Autoantigens

2011
  +4 more sources