Expression of citrulline and homocitrulline residues in the lungs of non-smokers and smokers : implications for autoimmunity in rheumatoid arthritis [PDF]
, 2015 Introduction: Smoking is a well-established risk factor for rheumatoid arthritis (RA), and it has been proposed that smoking-induced citrullination renders autoantigens immunogenic.
Bracke, Ken +8 more
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PLoS ONE, 2019 Autoantigens are the molecular targets in autoimmune diseases. They are a cohort of seemingly unrelated self-molecules present in different parts of the body, yet they can trigger a similar chain of autoimmune responses such as autoantibody production ...
Wei Zhang +4 more
doaj +1 more source
Revista Brasileira de Reumatologia, 2007 OBJECTIVES: to study the frequency and specificity of sclera-specific and non-sclera-specific autoantibodies in the sera of patients with anterior non-infectious scleritis. METHODS: prospective study involving 25 patients examined at the sector of Cornea
Wagner Koji Aragaki +4 more
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Nasal administration of glutamate decarboxylase (GAD65) peptides induces Th2 responses and prevents murine insulin-dependent diabetes. [PDF]
, 1996 We previously demonstrated that a spontaneous Th1 response against glutamate decarboxylase (GAD65) arises in NOD mice at four weeks in age and subsequently T cell autoimmunity spreads both intramolecularly and intermolecularly.
Atkinson, MA +6 more
core
Molecular mechanisms of autoimmunity triggered by microbial infection [PDF]
, 2005 Autoimmunity can be triggered by microbial infection. In this context, the discovery of Toll-like receptors (TLRs) provides new insights and research perspectives.
Anders, Hans-Joachim +3 more
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Citrullinated vimentin as an important antigen in immune complexes from synovial fluid of rheumatoid arthritis patients with antibodies against citrullinated proteins [PDF]
, 2010 Introduction: Rheumatoid arthritis (RA) is an inflammatory disease, which results in destruction of the joint. The presence of immune complexes (IC) in serum and synovial fluid of RA patients might contribute to this articular damage through different ...
De Ceuleneer, Marlies +5 more
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Neutrophil Extracellular Traps (NETs) Take the Central Stage in Driving Autoimmune Responses
Cells, 2020 Following fifteen years of research, neutrophil extracellular traps (NETs) are widely reported in a large range of inflammatory infectious and non-infectious diseases. Cumulating evidences from in vitro, in vivo and clinical diagnostics suggest that NETs
Esther Fousert, René Toes, Jyaysi Desai
doaj +1 more source
Serum thyroid hormone antibodies are frequent in patients with polyglandular autoimmune syndrome type 3, particularly in those who require thyroxine treatment [PDF]
, 2017 Polyglandular autoimmune syndrome (PAS) type 3 consists of autoimmune thyroid disease (AITD) coexisting with ≥1 non-thyroidal autoimmune disease (NTAID) other than Addison’s disease and hypoparathyroidism. We evaluated the prevalence and repertoire of
Benvenga, Salvatore +8 more
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Autoimmunity, Autoinflammation, and Infection in Uveitis [PDF]
, 2018 Funding/Support: No funding or grant support. Financial Disclosures: John V. Forrester has received an honorarium for lecturing from Janssen (London, UK). Lucia Kuffova has undertaken consultancy work for Abbvie (London, UK). Andrew D.
Dick, Andrew D. +2 more
core +4 more sources
Clinical and Translational Discovery, 2022 Coronavirus disease 2019 (COVID‐19) and the Gaucher disease (GD) exhibit lot of resemblances in induction of innate and adaptive immune inflammation that include the immune cells activation and the massive generation of pro‐inflammatory cytokines ...
Manoj Kumar Pandey
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