Results 41 to 50 of about 76,321 (240)

Autofluorescence of Model Polyethylene Terephthalate Nanoplastics for Cell Interaction Studies

Nanomaterials, 2022
This work contributes to fill one of the gaps regarding nanoplastic interactions with biological systems by producing polyethylene terephthalate (PET) model nanoplastics, similar to those found in the marine environment, by means of a fast top-down ...
Francesca Lionetto, Maria Giulia Lionetto, Claudio Mele, Carola Esposito Corcione, Sonia Bagheri, Gayatri Udayan, Alfonso Maffezzoli   +6 more
doaj   +1 more source

Paracrine Factor Local Gradient‐Generating System for Engineering Perfusable Vascularized Hepatocyte Tissues with Perfusion‐Induced Proliferation

Advanced Healthcare Materials, EarlyView.
A paracrine factor local gradient (PFLG)‐generating system enables microvessel penetration across 3D hepatocyte tissues. The resulting vascularized constructs recapitulate hepatic sinusoidal hepatocyte—endothelial contact architecture and enhance hepatic functions in vitro.
Yen‐Hsiang Huang, Tadahiro Yamashita, Ryo Sudo   +2 more
wiley   +1 more source

Fundus Autofluorescence

Delhi Journal of Ophthalmology, 2013
Fundus Autofluorescence (FAF) is a unique in vivo method of fundus imaging. Although it has been an area of active research over the last half a century, its only in the past decade that major advances have been made in its clinical application. The imaging has its basis in the mapping of normal and abnormal fluorophores in various retinal conditions ...
Vivek Pravin Dave, Rajeev R. Pappuru
openaire   +4 more sources

Identification of Binding Regions of Bilirubin in the Ligand-Binding Pocket of the Peroxisome Proliferator-Activated Receptor-A (PPARalpha)

Molecules, 2021
Recent work has shown that bilirubin has a hormonal function by binding to the peroxisome proliferator-activated receptor-α (PPARα), a nuclear receptor that drives the transcription of genes to control adiposity.
Darren M. Gordon, Stephen H. Hong, Zachary A. Kipp, Terry D. Hinds   +3 more
doaj   +1 more source

Skin‐Interfaced Therapeutic Patches for Wound Fluid Management and Transdermal Drug Delivery

Advanced Healthcare Materials, EarlyView.
This study presents an integrated skin‐interfaced device combining microfluidics, hydrogel film technology, flexible electronics, and iontophoresis‐based transdermal delivery of PDRN to enhance wound healing. The device effectively manages wound fluid, maintains optimal moisture, and non‐invasively delivers therapeutic drugs.
Dongjun Han, Donghyun Kim, Haram Lee, Dong‐Wook Park, Sung Soo Kwak, Joohee Kim   +5 more
wiley   +1 more source

A Versatile Engineering Platform for the Fabrication of Prosthetic Venous Valves Using Electrospinning

Advanced Healthcare Materials, EarlyView.
Percutaneous prosthetic venous valves are fabricated by embedding stents in an electrospun matrix that extends luminally to form leaflets. The design shields leaflets from hyperplastic cells, isolates struts from blood contact, and avoids discrete anchoring points.
Dario Arcuti, Salma Mansi, Dominic Biebl, Malin Reuter, Maximilian Grab, José Carlos Rodríguez‐Cabello, Petra Mela   +6 more
wiley   +1 more source

Fingertip skin autofluorescence as a non‐invasive marker for vascular complications in patients with type 2 diabetes

Journal of Diabetes Investigation
Aims/Introduction This study aimed to investigate whether non‐invasive fingertip autofluorescence can evaluate micro‐ and macrovascular complications in patients with type 2 diabetes. Materials and Methods This multicenter cross‐sectional study recruited
Minoru Takeshita, Takeshi Matsumura, Aiko Arimura, Hiroyuki Takahashi, Yoshimi Muta, Shigeru Kawade, Dai Yamagami, Takahisa Deguchi, Tatsuya Kondo, Mikihiro Yamanaka, Ryoji Nagai, Daiji Kawanami, Toshihiko Yanase, Takashi Nomiyama, Yoshihiko Nishio, Eiichi Araki, Naoto Kubota   +16 more
doaj   +1 more source

A Modular Bioinstructive Platform Reveals Mechanistic Insights into Additive‐Free, Topography‐Driven Osteogenesis

Advanced Healthcare Materials, EarlyView.
Engineered microparticle topographies direct human mesenchymal stem cell osteogenesis without biochemical additives. This osteogenic commitment is driven by canonical Hedgehog signaling and followed by temporal IGF‐II engagement. Two‐photon polymerization demonstrates spatial control, enabling the engineering of topographical gradients that pattern ...
Fatmah I. Ghuloum, Leo A. H. Zeef, Lee A. Stevens, Marco A. N. Domingos, Susan J. Kimber, Mahetab H. Amer   +5 more
wiley   +1 more source

A robust method for autofluorescence-free immunofluorescence using high-speed fluorescence lifetime imaging microscopy

Scientific Reports
Autofluorescence from endogenous biomolecules presents a significant challenge in immunofluorescence microscopy, often severely hindering the detection of specific fluorescence signals.
Wonsang Hwang, Tyler McPartland, Sinyoung Jeong, Conor L. Evans   +3 more
doaj   +1 more source

Near-Infrared Autofluorescence Imaging of Nuclei in Living Plant Roots

Bio-Protocol
In live-cell imaging, autofluorescence is often regarded as a negative factor that interferes with the accurate visualization of target fluorescence due to a phenomenon known as crosstalk.
Akira Yoshinari, Masayoshi Nakamura
doaj   +1 more source