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Thyroid ultrasonography reporting: consensus of Italian Thyroid Association (AIT), Italian Society of Endocrinology (SIE), Italian Society of Ultrasonography in Medicine and Biology (SIUMB) and Ultrasound Chapter of Italian Society of Medical Radiology (SIRM) [PDF]

open access: yes, 2018
Thyroid ultrasonography (US) is the gold standard for thyroid imaging and its widespread use is due to an optimal spatial resolution for superficial anatomic structures, a low cost and the lack of health risks.
Cantisani, V.   +11 more
core   +1 more source

A Case of Statin-Associated Autoimmune Myopathy. [PDF]

open access: yes, 2017
A 70-year-old previously independent man developed progressive proximal leg weakness resulting in a fall at home suffering traumatic brain injury. He was prescribed a statin medication two years prior, but this was discontinued on admission to the ...
Dokukin, Andrei N   +6 more
core   +3 more sources

Can unilateral, progressive or sudden hearing loss be immune-mediated in origin? [PDF]

open access: yes, 2017
OBJECTIVE: The aim of the present study was to demonstrate that the positivity of nonspecific immunological tests could be found not only in bilateral hearing loss but also in unilateral cases, either sudden or progressive. METHOD: An observational case
Atturo, Francesca   +4 more
core   +1 more source

Parkinson's disease: autoimmunity and neuroinflammation [PDF]

open access: yes, 2016
Parkinson's disease is a neurodegenerative disease that causes the death of dopaminergic neurons in the substantia nigra. The resulting dopamine deficiency in the basal ganglia leads to a movement disorder that is characterized by classical parkinsonian ...
CINIGLIO APPIANI, MARIO   +9 more
core   +1 more source

Thyroid Autoantibodies Display both “Original Antigenic Sin” and Epitope Spreading

open access: yesFrontiers in Immunology, 2017
Evidence for original antigenic sin in spontaneous thyroid autoimmunity is revealed by autoantibody interactions with immunodominant regions on thyroid autoantigens, thyroglobulin (Tg), thyroid peroxidase (TPO), and the thyrotropin receptor (TSHR) A ...
Sandra M. McLachlan, Basil Rapoport
doaj   +1 more source

Comprehensive characterization of ubiquitinome of human colorectal cancer and identification of potential survival-related ubiquitination

open access: yesJournal of Translational Medicine, 2022
Background According to the Global Cancer Statistics in 2020, the incidence and mortality of colorectal cancer (CRC) rank third and second among all tumors.
Wei Zhang   +11 more
doaj   +1 more source

An antigen-driven B-cell response within the salivary glands of patients with Sjögren’s syndrome [PDF]

open access: yes, 2002
Infection with a bacterium or virus induces the production of antibodies, specialised protein molecules that bind to and eliminate the microorganism.
Berek, C., Stott, D.I.
core  

Emerging immunopharmacological targets in multiple sclerosis. [PDF]

open access: yes, 2015
Inflammatory demyelination of the central nervous system (CNS) is the hallmark of multiple sclerosis (MS), a chronic debilitating disease that affects more than 2.5 million individuals worldwide. It has been widely accepted, although not proven, that the
Abdolmohamad Rostami   +182 more
core   +2 more sources

CTLA-4: a negative regulator of autoimmune disease. [PDF]

open access: yes, 1996
CTLA-4, a CD28 homologue expressed on activated T cells, binds with high affinity to the CD28 ligands, B7-1 (CD80) and B7-2 (CD86). This study was designed to examine the role of CTLA-4 in regulating autoimmune disease.
Bluestone, JA   +4 more
core  

AKRs confer oligodendrocytes resistance to differentiation-stimulated ferroptosis

open access: yesRedox Biology
Ferroptosis is a recently characterized form of cell death that has gained attention for its roles in both pathological and physiological contexts. The existence of multiple anti-ferroptotic pathways in both neoplastic and healthy cells, along with the ...
Valentina Saverio   +7 more
doaj   +1 more source

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