Results 11 to 20 of about 800,435 (388)

Proteomic analysis of lysine 2-hydroxyisobutyryl in SLE reveals protein modification alteration in complement and coagulation cascades and platelet activation Pathways

open access: yesBMC Medical Genomics, 2023
Background Post-translational modifications (PTMs) are considered to be an important factor in the pathogenesis of Systemic lupus erythematosus (SLE).
Chaoying Kuang   +10 more
doaj   +1 more source

The Chromatin Accessibility Landscape of Peripheral Blood Mononuclear Cells in Patients With Systemic Lupus Erythematosus at Single-Cell Resolution

open access: yesFrontiers in Immunology, 2021
ObjectiveSystemic lupus erythematosus (SLE) is a complex autoimmune disease, and various immune cells are involved in the initiation, progression, and regulation of SLE.
Haiyan Yu   +10 more
doaj   +1 more source

Hashimoto's thyroiditis and autoimmune gastritis [PDF]

open access: yes, 2017
The term "thyrogastric syndrome" defines the association between autoimmune thyroid disease and chronic autoimmune gastritis (CAG), and it was first described in the early 1960s.
Brusca, Nunzia   +6 more
core   +5 more sources

The characteristics of extrachromosomal circular DNA in patients with end-stage renal disease

open access: yesEuropean Journal of Medical Research, 2023
Background End-stage renal disease (ESRD) is the final stage of chronic kidney disease (CKD). In addition to the structurally intact chromosome genomic DNA, there is a double-stranded circular DNA called extrachromosomal circular DNA (eccDNA), which is ...
Yue Peng   +12 more
doaj   +1 more source

Absolute quantification and characterization of oxylipins in lupus nephritis and systemic lupus erythematosus

open access: yesFrontiers in Immunology, 2022
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease with multi-organ inflammation and defect, which is linked to many molecule mediators. Oxylipins as a class of lipid mediator have not been broadly investigated in SLE.
Jingquan He   +13 more
doaj   +1 more source

Autoimmunity and Otolaryngology Diseases [PDF]

open access: yesJournal of Immunology Research, 2018
Many systemic autoimmune diseases have otolaryngology manifestations that could represent a diagnostic challenge for clinicians, as they often constitute an early sign of an otherwise asymptomatic autoimmune condition and may lead to delayed diagnosis and treatment.
Massimo Ralli   +4 more
openaire   +6 more sources

Systematic proteomics profiling of lysine crotonylation of the lung at Pseudoglandular and Canalicular phases in human fetus

open access: yesProteome Science, 2023
Lung tissue is an important organ of the fetus, and genomic research on its development has improved our understanding of the biology of this tissue. However, the proteomic research of developing fetal lung tissue is still very scarce.
Wei Wang   +9 more
doaj   +1 more source

Emerging patterns of genetic overlap across autoimmune disorders. [PDF]

open access: yes, 2012
Most of the recently identified autoimmunity loci are shared among multiple autoimmune diseases. The pattern of genetic association with autoimmune phenotypes varies, suggesting that certain subgroups of autoimmune diseases are likely to share ...
Criswell, Lindsey A   +1 more
core   +1 more source

Serum thyroid hormone antibodies are frequent in patients with polyglandular autoimmune syndrome type 3, particularly in those who require thyroxine treatment [PDF]

open access: yes, 2017
Polyglandular autoimmune syndrome (PAS) type 3 consists of autoimmune thyroid disease (AITD) coexisting with ≥1 non-thyroidal autoimmune disease (NTAID) other than Addison’s disease and hypoparathyroidism. We evaluated the prevalence and repertoire of
Benvenga, Salvatore   +8 more
core   +1 more source

Mechanism-based strategies for the management of autoimmunity and immune dysregulation in primary immunodeficiencies [PDF]

open access: yes, 2016
A broad spectrum of autoimmunity is now well described in patients with primary immunodeficiencies (PIDs). Management of autoimmune disease in the background of PID is particularly challenging given the seemingly discordant goals of immune support and ...
Cooper, Megan A   +4 more
core   +2 more sources

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