Results 41 to 50 of about 9,492,165 (393)
Stem Cell Research, 2021 Systemic lupus erythematosus (SLE) is a heterogeneous, autoimmune disease that can affect multiple organs and systems such as skin, joints, kidneys, hematologic system or central nervous system.
Dandan Li +10 more
doaj
Advanced Biophotonics techniques for cell and molecules manipulation associated with cancer and autoimmune diseases: the role of optical tweezers [PDF]
arXiv, 2021 Biophotonic techniques are growing in rapid rhythms enabling the monitoring of subcellular structures and non-invasive theranostic interventions in cancer and autoimmune diseases. The integration of Biophotonics with nanotechnology and biosensors brings a revolution in the micro- and nano-world with new optical tools.
arxiv
Genetic and Epigenetic Fine-Mapping of Causal Autoimmune Disease Variants
Nature, 2014 Genome-wide association studies have identified loci underlying human diseases, but the causal nucleotide changes and mechanisms remain largely unknown.
K. Farh +29 more
semanticscholar +1 more source
Hereditas, 2021 Background Autosomal dominant osteopetrosis type II (ADO2) is a genetically and phenotypically metabolic bone disease, caused by osteoclast abnormalities.
Chunhong Li +6 more
doaj +1 more source
Enhancing Medical Image Segmentation: Optimizing Cross-Entropy Weights and Post-Processing with Autoencoders [PDF]
arXiv, 2023 The task of medical image segmentation presents unique challenges, necessitating both localized and holistic semantic understanding to accurately delineate areas of interest, such as critical tissues or aberrant features. This complexity is heightened in medical image segmentation due to the high degree of inter-class similarities, intra-class ...
arxiv
Reengineering chimeric antigen receptor T cells for targeted therapy of autoimmune disease
Science, 2016 Engineering T cells to treat autoimmunity Autoimmune diseases such as lupus and rheumatoid arthritis lack therapies that specifically target only the disease-causing cells.
C. Ellebrecht +11 more
semanticscholar +1 more source
Autoimmune Disease-Associated Hypertension
Current Hypertension Reports, 2019 Purpose of ReviewTo highlight important new findings on the topic of autoimmune disease-associated hypertension.Recent FindingsAutoimmune diseases including systemic lupus erythematosus and rheumatoid arthritis are associated with an increased risk for ...
V. Wolf, M. Ryan
semanticscholar +1 more source
MicroRNA in autoimmunity and autoimmune diseases
Journal of Autoimmunity, 2009 MicroRNAs (miRNAs) are small conserved non-coding RNA molecules that post-transcriptionally regulate gene expression by targeting the 3' untranslated region (UTR) of specific messenger RNAs (mRNAs) for degradation or translational repression.
Department of Oral Surgery & Diagnostic Sciences, University of Florida, Gainesville, FL, USA ( host institution ) +3 more
openaire +4 more sources
Autoimmune Disease Genetics [PDF]
Clinical and Developmental Immunology, 2012 Genetic risk factors play an important role in autoimmune disease susceptibility. Recent advances genotyping techniques, statistical methods, and the organization of large patient cohorts have facilitated explosive progress in this field, and our understanding of the genetic architecture of human autoimmunity is rapidly expanding.
Mohammed Tikly +3 more
openaire +3 more sources
MIRACLE: Multi-task Learning based Interpretable Regulation of Autoimmune Diseases through Common Latent Epigenetics [PDF]
arXiv, 2023 DNA methylation is a crucial regulator of gene transcription and has been linked to various diseases, including autoimmune diseases and cancers. However, diagnostics based on DNA methylation face challenges due to large feature sets and small sample sizes, resulting in overfitting and suboptimal performance. To address these issues, we propose MIRACLE,
arxiv