Results 51 to 60 of about 9,974,127 (411)

Screening for type 1 diabetes-, thyroid-, gastric-, and adrenal-specific humoral autoimmunity in 529 children and adolescents with celiac disease at diagnosis identifies as positive one in every nine patients [PDF]

open access: yes, 2016
No abstract ...
Anania, Caterina   +9 more
core   +1 more source

Multiomics landscape of the autosomal dominant osteopetrosis type II disease-specific induced pluripotent stem cells

open access: yesHereditas, 2021
Background Autosomal dominant osteopetrosis type II (ADO2) is a genetically and phenotypically metabolic bone disease, caused by osteoclast abnormalities.
Chunhong Li   +6 more
doaj   +1 more source

Autoimmune Disease-Associated Hypertension

open access: yesCurrent Hypertension Reports, 2019
Purpose of ReviewTo highlight important new findings on the topic of autoimmune disease-associated hypertension.Recent FindingsAutoimmune diseases including systemic lupus erythematosus and rheumatoid arthritis are associated with an increased risk for ...
V. Wolf, M. Ryan
semanticscholar   +1 more source

MicroRNA in autoimmunity and autoimmune diseases

open access: yesJournal of Autoimmunity, 2009
MicroRNAs (miRNAs) are small conserved non-coding RNA molecules that post-transcriptionally regulate gene expression by targeting the 3' untranslated region (UTR) of specific messenger RNAs (mRNAs) for degradation or translational repression.
Department of Oral Surgery   +4 more
openaire   +4 more sources

Autoimmune Disease Genetics [PDF]

open access: yesClinical and Developmental Immunology, 2012
Genetic risk factors play an important role in autoimmune disease susceptibility. Recent advances genotyping techniques, statistical methods, and the organization of large patient cohorts have facilitated explosive progress in this field, and our understanding of the genetic architecture of human autoimmunity is rapidly expanding.
Mohammed Tikly   +3 more
openaire   +3 more sources

Quality of life in mild and severe alopecia areata patients

open access: yesInternational Journal of Women's Dermatology, 2018
Background: Alopecia areata is a relapsing hair disorder characterized by a sudden hairloss and has a considerable impact on patient’s quality of life. The goal of this study was to determine quality of life among patients with mild and severe forms of ...
Robabeh Abedini   +5 more
doaj   +1 more source

Eosinophils in Autoimmune Diseases [PDF]

open access: yesFrontiers in Immunology, 2017
Eosinophils are multifunctional granulocytes that contribute to initiation and modulation of inflammation. Their role in asthma and parasitic infections has long been recognized. Growing evidence now reveals a role for eosinophils in autoimmune diseases.
Diny, Nicola L.   +2 more
openaire   +5 more sources

Sarcoidosis as an Autoimmune Disease [PDF]

open access: yesFrontiers in Immunology, 2020
Despite the large number of performed studies, the etiology and pathogenesis of sarcoidosis still remain unknown. Most researchers allude to the possible autoimmune or immune-mediated genesis of the disease. This review attempts an integral analysis of currently available information suggesting an autoimmune genesis of sarcoidosis and is divided into ...
Anna A. Starshinova   +15 more
openaire   +4 more sources

The cytoskeletal control of B cell receptor and integrin signaling in normal B cells and chronic lymphocytic leukemia

open access: yesFEBS Letters, EarlyView.
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley   +1 more source

Limited statistical evidence for shared genetic effects of eQTLs and autoimmune disease-associated loci in three major immune cell types

open access: yesNature Genetics, 2017
Most autoimmune-disease-risk effects identified by genome-wide association studies (GWAS) localize to open chromatin with gene-regulatory activity. GWAS loci are also enriched in expression quantitative trait loci (eQTLs), thus suggesting that most risk ...
S. Chun   +7 more
semanticscholar   +1 more source

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