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Biomarkers in autoimmune diseases of the central nervous system
The autoimmune diseases of the central nervous system (CNS) represent individual heterogeneity with different disease entities. Although clinical and imaging features make it possible to characterize larger patient cohorts, they may not provide ...
Fenghe Zhang +4 more
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Prominent urinary dysfunction and delayed antibody detection in patients with glial fibrillary acidic protein astrocytopathy: a case series analysis [PDF]
Background Glial fibrillary acidic protein astrocytopathy (GFAP-A) is a rare central nervous system (CNS) autoimmune disorder with highly heterogeneous presentations.
Zhenyu Niu +11 more
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Neuroprotective effects of melatonin in neurodegenerative and autoimmune central nervous system diseases [PDF]
The suprachiasmatic nucleus (SCN) in the anterior hypothalamus is the major circadian pacemaker in humans. Melatonin is a key hormone secreted by the pineal gland in response to darkness. Light-induced stimuli are transmitted along the retinohypothalamic
Jung-Won Shin
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Research progress of gut microbiome in autoimmune diseases of nervous system
Gut microbiome is the most direct external environment of human body, which plays a vital role in maintaining human health. Gut microbiome maintains the homeostasis of the human immune system, which can coexist with the host and affect the nutrition ...
TANG Shi, FENG Jin⁃zhou, QIN Xin⁃yue
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Regulatory T cells (Tregs) can eliminate autoreactive lymphocytes, induce self-tolerance, and suppress the inflammatory response. Mitochondria, as the energy factories of cells, are essential for regulating the survival, differentiation, and function of ...
Aoya Han +8 more
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Corticosteroid Treatment in Autoimmune Encephalitis [PDF]
An increasing number of neuronal autoantibodies which target cell surface or synaptic proteins have been discovered over the last decade. Autoimmune encephalitis refers to this new category of autoimmune-mediated neurological disorders, which involve the
Jun-Sang Sunwoo
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Perturbed expression of microRNAs (miRs) has been reported in different diseases including autoimmune and chronic inflammatory disorders. In this study, we investigated the expression of miR-25-3p and its targets in the central nervous system (CNS ...
Ameneh Zare-Chahoki +4 more
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Autoimmune Disorders of the Nervous System: Pathophysiology, Clinical Features, and Therapy
Remarkable discoveries over the last two decades have elucidated the autoimmune basis of several, previously poorly understood, neurological disorders.
Satyakam Bhagavati
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Introduction: Numerous studies have found an association between autoimmune diseases of the nervous system (ADNS) and schizophrenia (SCZ), but the findings remain controversial.
Yiting Cao +5 more
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Objective To summarize the clinical features of anti⁃leucine⁃rich⁃glioma⁃inactivation 1 (LGI1) antibody associated encephalitis. Methods and Results A total of 13 patients with anti ⁃ LGI1 antibody associated encephalitis were admitted to Huai'an No.
PAN He⁃yue +5 more
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