Results 231 to 240 of about 196,414 (282)

Practical Approach to Managing SCIg Treatment in Patients With Chronic Inflammatory Demyelinating Polyneuropathy

open access: yesMuscle &Nerve, EarlyView.
ABSTRACT Introduction/Aims Guidelines for the management of chronic inflammatory demyelinating polyneuropathy (CIDP) recommend corticosteroids, intravenous immunoglobulin (IVIg), or plasma exchange for first‐line therapies and subcutaneous immunoglobulin (SCIg) as a maintenance option.
Tuan Vu   +10 more
wiley   +1 more source

No General Association Between Myositis Antibodies and Electromyography Findings

open access: yesNeurology and Clinical Neuroscience, EarlyView.
ABSTRACT Objective Myositis‐specific antibodies (MSAs), myositis‐associated antibodies (MAAs), and concentric needle electromyography (EMG) are routinely used in the differential diagnosis of myositis. Their mutual relationship, particularly between MSAs/MAAs and EMG findings, remains unclear.
Benedict Kleiser   +7 more
wiley   +1 more source

Wasting syndrome as a predictive factor for adverse health outcomes in older adults: A prospective cohort study

open access: yesNutrition in Clinical Practice, EarlyView.
Abstract Wasting syndrome (WS), also known as unintentional weight loss, is defined as a 5% reduction in body weight over a period of 6–12 months. The mortality associated with WS in older adults has not been adequately explored. The objective of this study was to investigate this relationship in hospitalized older individuals over an 18‐month period ...
Roana Carolina Bezerra dos Santos   +7 more
wiley   +1 more source

Regulatory B cells in the central nervous system: From immune regulation to neuroprotection

open access: yesNeuroprotection, EarlyView.
Neuroinflammatory mechanisms and the therapeutic potential of regulatory B cells (Bregs). Following brain Injury (left panel) blood–brain barrier disruption facilitates the infiltration of peripheral leukocytes, including effector B cells (Beff) and effector T cells (Teff). This process triggers the activation of macrophages, astrocytes, and microglia,
Luiza Stanaszek, Miroslaw Janowski
wiley   +1 more source

Gene List Selection Matters: Missed Diagnoses in Prenatal Exome Sequencing—PanelApp R21 and HPO‐Driven Versus OMIM‐Based Gene Lists

open access: yesPrenatal Diagnosis, EarlyView.
ABSTRACT Objective To evaluate whether the causative variants found upon clinical exome sequencing in fetuses affected with selected structural anomalies would also be detected if PanelApp‐R21 or Human Phenotype Ontology (HPO)‐driven gene selection terms were applied instead.
Victoria Ardiles‐Ruesjas   +7 more
wiley   +1 more source

Challenges and Opportunities in State‐of‐the‐Art Proteomics Analysis for Biomarker Development From Plasma Extracellular Vesicles

open access: yesPROTEOMICS, EarlyView.
ABSTRACT Extracellular vesicles (EVs) are membrane‐bound particles secreted by cells, playing crucial roles in intercellular communication. The composition of EVs can undergo changes in response to stress and disease conditions, making them excellent biomarker candidates.
Panshak P. Dakup   +11 more
wiley   +1 more source

Advancing Extracellular Vesicle Research: A Review of Systems Biology and Multiomics Perspectives

open access: yesPROTEOMICS, EarlyView.
ABSTRACT Extracellular vesicles (EVs) are membrane‐bound vesicles secreted by various cell types into the extracellular space and play a role in intercellular communication. Their molecular cargo varies depending on the cell of origin and its functional state.
Gloria Kemunto   +2 more
wiley   +1 more source

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