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Autoimmune diseases of the peripheral nervous system
Autoimmunity Reviews, 2012Autoimmune-mediated diseases targeting the peripheral nerve represent a group of disorders often associated with high clinical disability. At present, therapeutic options are limited. The application of innovative and cutting-edge technologies to the study of immune-mediated disorders of the peripheral nervous system (PNS) have generated a better ...
Bernd C, Kieseier +2 more
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Biochemical Markers of Autoimmune Diseases of the Nervous System
Current Pharmaceutical Design, 2012Biochemical biomarkers are important candidates for the diagnosis and prognosis of neurological diseases of autoimmune etiology, since they may reflect the presence, nature and intensity of certain immune responses caused by both genetic and environmental processes.
Hayrettin, Tumani +1 more
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Use of complementary medicine in autoimmune diseases of the nervous system.
Vestnik nevrologii, psihiatrii i nejrohirurgii (Bulletin of Neurology, Psychiatry and Neurosurgery), 2022Autoimmune diseases of the nervous system are characterized by the formation of a pronounced neurological deficit and often lead to disability. The attention of doctors and researchers is increasingly attracted to complementary medicine as an adjuvant r preventive therapy for various diseases, including autoimmune diseases.
Yu. О. Novikov +2 more
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Statins in the treatment of central nervous system autoimmune disease
Journal of Neuroimmunology, 2006Statins, inhibitors of 3-hydroxy-3-methylglutaryl coenzyme A reductase, are widely prescribed for their cholesterol-lowering properties to reduce atherogenesis and cardiovascular morbidity. Over recent years, statins have also been shown to exert pleiotropic immunomodulatory effects that might be of therapeutic benefit in autoimmune disorders.
Martin S, Weber +8 more
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Experimental models of spontaneous autoimmune disease in the central nervous system
Journal of Molecular Medicine, 2007Animal models have become essential tools for studying the human autoimmune disease. They are of vital importance in explorations of disease aspects, where, for diverse reasons, human material is unavailable. This is especially true for disease processes preceding clinical diagnosis and for tissues, which are inaccessible to routine biopsy.
Gurumoorthy, Krishnamoorthy +2 more
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B cells in spontaneous autoimmune diseases of the central nervous system
Molecular Immunology, 2011B cells and their secreted products participate in the intricate network of pathogenic and regulatory immune responses. In human autoimmune diseases like rheumatoid arthritis, systemic lupus erythematosus and type 1 diabetes, a role for B cells and antibodies is well established.
Berer, K. +2 more
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Childhood autoimmune neurologic diseases of the central nervous system
Neurologic Clinics, 2003An autoimmune mechanism for ADEM and MS can be supported by the similar patterns of pathologic changes seen in both diseases with the animal model EAE induced by inoculating animals with nervous tissue and the occurrence of ADEM in patients exposed to nervous tissue during vaccination.
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Autoimmune mechanisms in the pathogenesis of paraneoplastic nervous system disease
Clinical Neurology and Neurosurgery, 1995There is compelling circumstantial evidence that humoral autoimmune response may be involved in the generation of paraneoplastic neurologic syndromes (PNS). However, still it is unproven whether the autoantibody is pathogenic or represents an epiphenomenon to the actual disease process.
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