Alopecia areata: a multifactorial autoimmune condition [PDF]
Alopecia areata is an autoimmune disease that results in non-scarring hair loss, and it is clinically characterised by small patches of baldness on the scalp and/or around the body. It can later progress to total loss of scalp hair (Alopecia totalis) and/
Butcher, John P. +3 more
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Autoimmune Diseases of the Nervous System: Problem Statement and Prospects
This review highlights the achievements in the field of autoimmune diseases of the nervous system over the last 15 years. It became possible to deepen the understanding of medical and social significance of these diseases, form the concept of nosologic unit heterogeneity, describe new and atypical forms ofdemyelinating diseases of the central and ...
M A, Piradov, N A, Suponeva
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Infectious diseases and autoimmunity [PDF]
Introduction: Autoimmunity occurs when the immune system recognizes and attacks host tissue. In addition to genetic factors, environmental triggers (in particular viruses, bacteria and other infectious pathogens) are thought to play a major role in the ...
Deidda, Silvia +3 more
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Hyperreflective focuses as a biomarker of multiple sclerosis progression
Purpose: to identify the intraretinal hyperreflective foci (HRF), their specific characteristics, localization features and correlations with the duration of the disease, type of course and previous episodes of optic neuritis (ON) in multiple sclerosis ...
A. Zh. Fursova +8 more
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Rare complications of Sjögren’s syndrome in a female patient
Sjögren’s syndrome (SjS) is a systemic autoimmune disease, most common in middle-aged women, characterized by chronic inflammation of exocrine glands. It can present by itself or alongside other autoimmune diseases. Main symptoms are dry eyes and mouth,
Tin Rosan, Jana Jelenić, Marija Bakula
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Vitamin D deficiency has been linked to an increased risk of a wide range of adverse health outcomes. The active form of vitamin D has an important role in calcium metabolism and in bone mineralisation, but the evidence for other health outcomes is mixed,
Geldenhuys, Sian +3 more
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Progress on single-cell sequencing technology in central nervous system autoimmune diseases
Central nervous system (CNS) autoimmune diseases are characterized by complex pathogenesis involving interactions among diverse immune cells originating from both the CNS and the peripheral immune system.
WENG Shi-wen +3 more
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Induced CNS expression of CXCL1 augments neurologic disease in a murine model of multiple sclerosis via enhanced neutrophil recruitment. [PDF]
Increasing evidence points to an important role for neutrophils in participating in the pathogenesis of the human demyelinating disease MS and the animal model EAE.
Doty, Daniel J +7 more
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Recombinant human PDCD5 (rhPDCD5) protein is protective in a mouse model of multiple sclerosis. [PDF]
BackgroundIn multiple sclerosis (MS) and its widely used animal model, experimental autoimmune encephalomyelitis (EAE), autoreactive T cells contribute importantly to central nervous system (CNS) tissue damage and disease progression. Promoting apoptosis
Chen, Yingyu +3 more
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Mycophenolate mofetil in the treatment of pediatric autoimmune central nervous system disease [PDF]
This commentary is on the original article by Nosadini et al. on pages 458–468 of this issue.
Cory Stingl, Heather Van Mater
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