Results 11 to 20 of about 153,226 (196)
Diagnostics, 2023 Anti-neutrophil cytoplasmic antibodies (ANCA) directed to proteinase 3 (PR3) represent highly established markers for patients with ANCA-associated vasculitis (AAV). PR3-ANCA have also demonstrated utility in the management of inflammatory bowel disease (
Carmen Andalucía +5 more
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dcHiC detects differential compartments across multiple Hi-C datasets
Nature Communications, 2022 The organisation of mammalian genomes plays a role in many biological processes. Here the authors report dcHiC, a tool which uses a multivariate distance measure to identify changes in compartmentalisation among multiple genome-wide chromatin contact ...
Abhijit Chakraborty +2 more
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Cell Communication and Signaling, 2019 Background The airway epithelium is a major target tissue in respiratory infections, and its antiviral response is mainly orchestrated by the interferon regulatory factor-3 (IRF3), which subsequently induces type I (β) and III (λ) interferon (IFN ...
Engin Baturcam +7 more
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Pathogenic mechanisms of IgE-mediated inflammation in self-destructive autoimmune responses
Autoimmunity, 2017 Autoantibodies of the IgG subclass are pathogenic in a number of autoimmune disorders such as systemic lupus erythomatosus. The presence of circulating IgE autoantibodies in autoimmune patients has also been known for almost 40 years.
Rachel Ettinger +6 more
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The kaleidoscope of autoimmunity: multiple autoimmune syndromes and familial autoimmunity
Expert Review of Clinical Immunology, 2007 Three related lines of evidence sustain the common origin for autoimmune diseases (ADs). First, the clinical evidence corresponding to the kaleidoscope of autoimmunity, which is the co-occurrence of various ADs within an individual or co-occurrence within members of a nuclear family.
Anaya, Juan-Manuel +4 more
openaire +2 more sources
Journal of Clinical and Translational Science, 2021 IMPACT: Better understanding of the factors impacting disease severity and immunological response of MS patients on disease modifying therapy will enable better recommendations for vaccination options and risk mitigation strategies OBJECTIVES/GOALS: The ...
Ahya S Ali, Yang Mao-Draayer
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International Journal of Dermatology, 1981 Peer Reviewed ; http://deepblue.lib.umich.edu/bitstream/2027.42/66083/1/j.1365-4362.1981.tb00393.x ...
King, Andrew J. +4 more
openaire +3 more sources
Journal of Immunology Research, 2017 Neutrophils are important effector cells of antimicrobial immunity in an acute inflammatory response, with a primary role in the clearance of extracellular pathogens.
Carina Kärrman Mårdh +6 more
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Pediatric Rheumatology Online Journal, 2022 Background Environmental exposures have been associated with the juvenile idiopathic inflammatory myopathies (JIIM). We undertook a questionnaire-based study to evaluate patient-reported exposures as possible risk factors for JIIM.
Jonathan C. Scalabrini +8 more
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Diagnostics, 2022 (1) Background: Anti-carbamylated protein (CarP) antibodies have been studied as novel markers to aid in the diagnosis and prognosis of rheumatoid arthritis.
Vincent Ricchiuti +6 more
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