Results 11 to 20 of about 9,092 (223)
α-Hydroxyketone Synthesis and Sensing by Legionella and Vibrio [PDF]
Bacteria synthesize and sense low molecular weight signaling molecules, termed autoinducers, to measure their population density and community complexity. One class of autoinducers, the α-hydroxyketones (AHKs), is produced and detected by the water-borne
Hubert Hilbi, André Tiaden
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Bacterial–Fungal Interactions in the Kelp Endomicrobiota Drive Autoinducer-2 Quorum Sensing [PDF]
Brown macroalgae are an essential component of temperate coastal ecosystems and a growing economic sector. They harbor diverse microbial communities that regulate algal development and health.
Anne Tourneroche +7 more
doaj +5 more sources
The Autoinducer-2 Exporter Superfamily [PDF]
The TqsA (YdgG) protein of <i>Escherichia coli</i> has been shown to export the autoinducer-2 (AI-2) molecule, a furanosyl borate diester that bears little resemblance to previously characterized biological molecules. TqsA belongs to a large superfamily, the AI-2 exporter (AI-2E) superfamily, of putative transporters with no other ...
Rettner, Rachael E, Saier, Milton H
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The Lantibiotic Mersacidin Is an Autoinducing Peptide [PDF]
ABSTRACT The lantibiotic (lanthionine-containing antibiotic) mersacidin is an antimicrobial peptide consisting of 20 amino acids and is produced by Bacillus sp. strain HIL Y-85,54728. The structural gene ( mrsA ) and the genes for producer self-protection, modification enzymes ...
Stephanie, Schmitz +4 more
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Quinolones: from antibiotics to autoinducers [PDF]
Since quinine was first isolated, animals, plants and microorganisms producing a wide variety of quinolone compounds have been discovered, several of which possess medicinally interesting properties ranging from antiallergenic and anticancer to antimicrobial activities.
Heeb S +5 more
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Quorum sensing in Vibrio fischeri: probing autoinducer-LuxR interactions with autoinducer analogs [PDF]
The Vibrio fischeri luminescence genes are activated by the transcription factor LuxR in combination with a diffusible signal compound, N-(3-oxohexanoyl) homoserine lactone, termed the autoinducer. We have synthesized a set of autoinducer analogs. Many analogs with alterations in the acyl side chain showed evidence of binding to LuxR.
A L, Schaefer +3 more
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Design, Synthesis, and Evaluation of Transition-State Analogs as Inhibitors of the Bacterial Quorum Sensing Autoinducer Synthase CepI [PDF]
Quorum sensing is a bacterial signaling system that involves the synthesis and detection of small signal molecules called autoinducers. A main class of autoinducers in Gram-negative bacteria are acylated homoserine lactones, produced by the LuxI family ...
Alec, Esposito +7 more
core +1 more source
Clinically significant pathogens such as Pseudomonas aeruginosa evade the effects of antibiotics using quorum sensing (QS) systems, making antimicrobial resistance (AMR) a persistent and potentially fatal global health issue.
Nosipho Wendy S’thebe +2 more
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Core Principles of Bacterial Autoinducer Systems [PDF]
SUMMARY Autoinduction (AI), the response to self-produced chemical signals, is widespread in the bacterial world. This process controls vastly different target functions, such as luminescence, nutrient acquisition, and biofilm formation, in different ways and integrates additional environmental and physiological cues.
Burkhard A. Hense, Martin Schuster
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The genus Nitrospira represents a dominant group of nitrite-oxidizing bacteria in natural and engineered ecosystems. This genus is phylogenetically divided into six lineages, for which vast phylogenetic and functional diversity has been revealed by ...
Norisuke Ushiki +5 more
doaj +1 more source

