Results 11 to 20 of about 7,703 (178)
The Autoinducer-2 Exporter Superfamily [PDF]
The TqsA (YdgG) protein of <i>Escherichia coli</i> has been shown to export the autoinducer-2 (AI-2) molecule, a furanosyl borate diester that bears little resemblance to previously characterized biological molecules. TqsA belongs to a large superfamily, the AI-2 exporter (AI-2E) superfamily, of putative transporters with no other ...
Rettner, Rachael E, Saier, Milton H
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Quinolones: from antibiotics to autoinducers [PDF]
Since quinine was first isolated, animals, plants and microorganisms producing a wide variety of quinolone compounds have been discovered, several of which possess medicinally interesting properties ranging from antiallergenic and anticancer to antimicrobial activities.
Heeb S +5 more
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Acyl-homoserine lactones (AHLs) are quorum sensing (QS) signaling molecules that mediate cell-to-cell communication in Gram-negative bacteria. Salmonella does not produce AHL, however, it can recognize AHLs produced by other species through SdiA protein ...
Deisy G. Carneiro +6 more
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Clinically significant pathogens such as Pseudomonas aeruginosa evade the effects of antibiotics using quorum sensing (QS) systems, making antimicrobial resistance (AMR) a persistent and potentially fatal global health issue.
Nosipho Wendy S’thebe +2 more
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The Lantibiotic Mersacidin Is an Autoinducing Peptide [PDF]
ABSTRACT The lantibiotic (lanthionine-containing antibiotic) mersacidin is an antimicrobial peptide consisting of 20 amino acids and is produced by Bacillus sp. strain HIL Y-85,54728. The structural gene ( mrsA ) and the genes for producer self-protection, modification enzymes ...
Stephanie, Schmitz +4 more
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Quorum sensing in Vibrio fischeri: probing autoinducer-LuxR interactions with autoinducer analogs [PDF]
The Vibrio fischeri luminescence genes are activated by the transcription factor LuxR in combination with a diffusible signal compound, N-(3-oxohexanoyl) homoserine lactone, termed the autoinducer. We have synthesized a set of autoinducer analogs. Many analogs with alterations in the acyl side chain showed evidence of binding to LuxR.
A L, Schaefer +3 more
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The genus Nitrospira represents a dominant group of nitrite-oxidizing bacteria in natural and engineered ecosystems. This genus is phylogenetically divided into six lineages, for which vast phylogenetic and functional diversity has been revealed by ...
Norisuke Ushiki +5 more
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498 Structural Determination of the CqsR CACHE Domain and its Autoinducer
OBJECTIVES/GOALS: Our goal is to determine the structure of the CACHE domain of the Vibrio cholerae quorum sensing receptor CqsR as well as its autoinducer (AI).
Andrew Guarnaccia +5 more
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Phage-Encoded LuxR-Type Receptors Responsive to Host-Produced Bacterial Quorum-Sensing Autoinducers
Quorum sensing (QS) is a process of cell-to-cell communication that bacteria use to orchestrate collective behaviors. QS relies on the cell-density-dependent production, accumulation, and receptor-mediated detection of extracellular signaling molecules ...
Justin E. Silpe, Bonnie L. Bassler
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Bacterial pheromones, mainly different homoserine lactones, are central to a number of bacterial signaling processes, including those involved in plant pathogenicity.
Andres Mäe +3 more
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