Results 11 to 20 of about 14,518 (211)
The Autoinducer-2 Exporter Superfamily [PDF]
The TqsA (YdgG) protein of <i>Escherichia coli</i> has been shown to export the autoinducer-2 (AI-2) molecule, a furanosyl borate diester that bears little resemblance to previously characterized biological molecules. TqsA belongs to a large superfamily, the AI-2 exporter (AI-2E) superfamily, of putative transporters with no other ...
Rettner, Rachael E, Saier, Milton H
openaire +4 more sources
Quinolones: from antibiotics to autoinducers [PDF]
Since quinine was first isolated, animals, plants and microorganisms producing a wide variety of quinolone compounds have been discovered, several of which possess medicinally interesting properties ranging from antiallergenic and anticancer to antimicrobial activities.
Heeb S +5 more
openaire +2 more sources
Clinically significant pathogens such as Pseudomonas aeruginosa evade the effects of antibiotics using quorum sensing (QS) systems, making antimicrobial resistance (AMR) a persistent and potentially fatal global health issue.
Nosipho Wendy S’thebe +2 more
doaj +1 more source
Quorum sensing in Vibrio fischeri: probing autoinducer-LuxR interactions with autoinducer analogs [PDF]
The Vibrio fischeri luminescence genes are activated by the transcription factor LuxR in combination with a diffusible signal compound, N-(3-oxohexanoyl) homoserine lactone, termed the autoinducer. We have synthesized a set of autoinducer analogs. Many analogs with alterations in the acyl side chain showed evidence of binding to LuxR.
A L, Schaefer +3 more
openaire +2 more sources
Saffron Alters Microbial Amino Acid Metabolism and Neurotransmitter Production in a Defined Gut Consortium. [PDF]
Graphical representation of the metabolic pathways modulated by saffron within defined microbial communities. In the tryptophan pathway, saffron decreased levels of tryptophan and anthranilic acid while increasing concentrations of indole‐3‐acetic acid and tryptamine.
Horvath AE +9 more
europepmc +2 more sources
Acyl-homoserine lactones (AHLs) are quorum sensing (QS) signaling molecules that mediate cell-to-cell communication in Gram-negative bacteria. Salmonella does not produce AHL, however, it can recognize AHLs produced by other species through SdiA protein ...
Deisy G. Carneiro +6 more
doaj +1 more source
Anti-Quorum-Sensing Potential of Ethanolic Extracts of Aromatic Plants from the Flora of Cyprus
Quorum sensing (QS) is a form of intra- and inter-species communication system employed by bacteria to regulate their collective behavior in a cell population-dependent manner. QS has been implicated in the virulence of several pathogenic bacteria.
Tolis Panayi +4 more
doaj +1 more source
Core Principles of Bacterial Autoinducer Systems [PDF]
SUMMARY Autoinduction (AI), the response to self-produced chemical signals, is widespread in the bacterial world. This process controls vastly different target functions, such as luminescence, nutrient acquisition, and biofilm formation, in different ways and integrates additional environmental and physiological cues.
Burkhard A. Hense, Martin Schuster
openaire +3 more sources
Caenorhabditis elegans Senses Bacterial Autoinducers [PDF]
ABSTRACT Pseudomonas aeruginosa uses virulence factors controlled by quorum sensing (QS) to kill Caenorhabditis elegans . Here we show that C.
Elmus, Beale +3 more
openaire +2 more sources
Sinorhizobium Meliloti, A Bacterium Lacking The Autoinducer-2 (AI-2) Synthase, Responds To AI-2 Supplied By Other Bacteria [PDF]
Many bacterial species respond to the quorum-sensing signal autoinducer-2 (AI-2) by regulating different niche-specific genes. Here, we show that Sinorhizobium meliloti, a plant symbiont lacking the gene for the AI-2 synthase, while not capable of ...
McAuley, J. R. +4 more
core +2 more sources

