Results 41 to 50 of about 9,092 (223)

Plant-Derived Natural Products as Sources of Anti-Quorum Sensing Compounds

Sensors, 2013
Quorum sensing is a system of stimuli and responses in relation to bacterial cell population density that regulates gene expression, including virulence determinants. Consequently, quorum sensing has been an attractive target for the development of novel
Kok-Gan Chan, Yee Meng Chong, Thiba Krishnan, Li Ying Tan, Wai-Fong Yin, Choon-Kook Sam, Chong-Lek Koh   +6 more
doaj   +1 more source

Promoter selectivity of the RhlR quorum-sensing transcription factor receptor in Pseudomonas aeruginosa is coordinated by distinct and overlapping dependencies on C4-homoserine lactone and PqsE.

PLoS Genetics, 2023
Quorum sensing is a mechanism of bacterial cell-cell communication that relies on the production and detection of small molecule autoinducers, which facilitate the synchronous expression of genes involved in group behaviors, such as virulence factor ...
Nicholas R Keegan, Nathalie J Colón Torres, Anne M Stringer, Lia I Prager, Matthew W Brockley, Charity L McManaman, Joseph T Wade, Jon E Paczkowski   +7 more
doaj   +1 more source

Evidence of autoinducer activity in naturally occurring biofilms [PDF]

FEMS Microbiology Letters, 2006
N-Acyl homoserine lactone (AHL) molecules have been shown to act as mediators of population density-dependent (quorum-sensing) gene expression in numerous Gram-negative bacteria. Functions associated with AHL include light production in Vibrio fischeri, expression of virulence factors in Pseudomonas aeruginosa, and conjugation in Agrobacterium ...
R J, McLean, M, Whiteley, D J, Stickler, W C, Fuqua   +3 more
openaire   +2 more sources

Characterization of Autoinducer-3 Structure and Biosynthesis in E. coli [PDF]

ACS Central Science, 2020
Escherichia coli is a common inhabitant of the human microbiota and a beacon model organism in biology. However, an understanding of its signaling systems that regulate population-level phenotypes known as quorum sensing remain incomplete. Here, we define the structure and biosynthesis of autoinducer-3 (AI-3), a metabolite of previously unknown ...
Chung Sub Kim, Alexandra Gatsios, Santiago Cuesta, Yick Chong Lam, Zheng Wei, Haiwei Chen, Regan M. Russell, Emilee E. Shine, Rurun Wang, Thomas P. Wyche, Grazia Piizzi, Richard A. Flavell, Noah W. Palm, Vanessa Sperandio, Jason M. Crawford   +14 more
openaire   +3 more sources

Stress and the periodontal diseases: Growth responses of periodontal bacteria to Escherichia coli stress-associated autoinducer and exogenous Fe [PDF]

, 2005
Psychological stress is known to increase the circulating levels of the catecholamine hormones noradrenaline and adrenaline, which have been shown to influence the growth of a large number of bacterial species by acting in a siderophore-like manner or by
Freestone, P. P E, Williams, P. H., Matthews, J. B., Roberts, A., Socransky, S. S., Chapple, I. L C   +5 more
core   +3 more sources

Exploiting quorum sensing interfering strategies in gram-negative bacteria for the enhancement of environmental applications

Frontiers in Microbiology, 2016
Quorum sensing (QS) is a widespread intercellular form of communication to coordinate physiological processes and cooperative activities of bacteria at the population level, and it depends on the production, secretion, and detection of small diffusible ...
Weiwei eZhang, Chenghua eLi
doaj   +1 more source

From Circuits to Symphonies: A Systems‐Engineering Blueprint for Multimicrobial Synthetic Biology

Advanced Science, EarlyView.
Engineering synthetic microbial consortia requires moving beyond intracellular genetic circuits toward coordinated multicellular design. A modular systems‐engineering framework is presented that integrates communication, temporal coordination, ecological structuring, and predictive modeling to guide application‐dependent consortium design ...
Miguel Fernández‐Niño, Ludger A. Wessjohann, José Manuel Guillamón, Daniela Burgos‐Toro, Silvia Moriano‐Gutiérrez, Giacomo Di Matteo, Zia‐ul Islam, Rinke van van Tatenhove‐Pel, Vanessa Rossetto Marcelino, Rodrigo Ledesma‐Amaro   +9 more
wiley   +1 more source

Autoinducers Act as Biological Timers in Vibrio harveyi

PLoS ONE, 2012
Quorum sensing regulates cell density-dependent phenotypes and involves the synthesis, excretion and detection of so-called autoinducers. Vibrio harveyi strain ATCC BAA-1116 (recently reclassified as Vibrio campbellii), one of the best-characterized model organisms for the study of quorum sensing, produces and responds to three autoinducers.
Anetzberger, C., Reiger, M., Fekete, A., Schell, U., Stambrau, N., Plener, L., Kopka, J., Schmitt-Kopplin, P., Hilbi, H., Jung, K.   +9 more
openaire   +5 more sources

Characterization of an Autoinducer of Penicillin Biosynthesis in Penicillium chrysogenum [PDF]

Applied and Environmental Microbiology, 2011
ABSTRACT Filamentous fungi produce an impressive variety of secondary metabolites; many of them have important biological activities. The biosynthesis of these secondary metabolites is frequently induced by plant-derived external elicitors and appears to also be regulated by internal inducers, which may work in a way similar to ...
Martín, Jorge, García Estrada, Carlos, Rumbero, Ángel, Recio, Eliseo, Albillos García, Silvia María, Ullán, Ricardo Vicente, Martín Martín, Juan Francisco   +6 more
openaire   +4 more sources

Challenges and Future Directives of Synthetic Biology in Engineering Plant–Microbe Partnerships for Sustainable Agriculture

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Synthetic biology has recently proven to be a valuable tool for enhancing agriculture even in the face of environmental and biological stresses. Understanding the challenges that militate synthetic biology will assist in ensuring safe, stable, and scalable crop production.
Ben Jesuorsemwen Enagbonma, Rebaona Reaobaka Molefe‐Madlaliso, Alaba Adewole Adebayo, Oghoye Priscilla Oyedoh, Godfrey Okainemen Oribhabor, Oluwaseun Emmanuel Shittu, Olubukola Oluranti Babalola   +6 more
wiley   +1 more source