Results 51 to 60 of about 14,518 (211)

Identifying Cytokine Motif‐Containing, Immunomodulatory Bacterial Proteins in Human Gut Microbiome

Advanced Science, EarlyView.
By building and constructing HMM (Upper left, blue), the authors identify CMCPs in bacteria genomes and CRC related metagenomes and enriched CRC‐related CMCPs (Upper right, blue). They analyze sequence and structural similarity of hits (Lower left, green), test function with engineered EcN delivered to tumors in a mouse tumor model (Lower right, pink ...
Ziyu Wang, Siqi Guo, Jing Li, Qianqian Huang, Jing Ning, Binbin Xia, Xun Lv, Xiang Liu, Zeyu Gao, Jine Li, Longchao Liu, Moshi Song, Jun Wang   +12 more
wiley   +1 more source

Functional analysis of the Pseudomonas aeruginosa autoinducer PAI [PDF]

Journal of Bacteriology, 1996
A series of structural analogs of the Pseudomonas aeruginosa autoinducer [PAI, N-3-oxo-dodecanoyl homoserine lactone] were obtained and tested for their ability to act as autoinducers in stimulating the expression of the gene for elastase (lasB) by measuring beta-galactosidase production from a lasB-lacZ gene fusion in the presence of the ...
L, Passador, K D, Tucker, K R, Guertin, M P, Journet, A S, Kende, B H, Iglewski   +5 more
openaire   +2 more sources

Quorum sensing signaling molecules produced by reference and emerging soft-rot bacteria (Dickeya and Pectobacterium spp.). [PDF]

PLoS ONE, 2012
BackgroundSeveral small diffusible molecules are involved in bacterial quorum sensing and virulence. The production of autoinducers-1 and -2, quinolone, indole and γ-amino butyrate signaling molecules was investigated in a set of soft-rot bacteria ...
Alexandre Crépin, Corinne Barbey, Amélie Beury-Cirou, Valérie Hélias, Laure Taupin, Sylvie Reverchon, William Nasser, Denis Faure, Alain Dufour, Nicole Orange, Marc Feuilloley, Karin Heurlier, Jean-François Burini, Xavier Latour   +13 more
doaj   +1 more source

Quorum Sensing in the Context of Food Microbiology [PDF]

, 2012
Food spoilage may be defined as a process that renders a product undesirable or unacceptable for consumption and is the outcome of the biochemical activity of a microbial community that eventually dominates according to the prevailing ecological ...
Nychas, George-John E., Skandamis, Panagiotis N.   +1 more
core   +2 more sources

Mechanism of Vibrio cholerae Autoinducer-1 Biosynthesis

ACS Chemical Biology, 2011
Vibrio cholerae, the causative agent of the disease cholera, uses a cell to cell communication process called quorum sensing to control biofilm formation and virulence factor production. The major V. cholerae quorum-sensing signal CAI-1 has been identified as (S)-3-hydroxytridecan-4-one, and the CqsA protein is required for CAI-1 production.
Wei, Yunzhou, Perez, Lark J., Ng, Wai-Leung, Semmelhack, Martin F., Bassler, Bonnie L.   +4 more
openaire   +2 more sources

The lux autoinducer-receptor interaction in Vibrio harveyi: binding parameters and structural requirements for the autoinducer [PDF]

Biochemical Journal, 1995
To assess the binding parameters and the structure-function relationship of the Vibrio harveyi lux autoinducer, N-(D-3-hydroxybutanoyl)homoserine lactone (D-HBHL), to light emission, a series of acylhomoserine lactone analogues were synthesized and their effects on the stimulation of luminescence of an autoinducer-deficient mutant of V.
J G, Cao, Z Y, Wei, E A, Meighen
openaire   +2 more sources

Directed evolution of Vibrio fischeri LuxR for increased sensitivity to a broad spectrum of acyl-homoserine lactones [PDF]

, 2005
LuxR-type transcriptional regulators play key roles in quorum-sensing systems that employ acyl-homoserine lactones (acyl-HSLs) as signal molecules.
Arnold, Frances H., Collins, Cynthia H., Leadbetter, Jared R.   +2 more
core  

A Modeling Approach Based on P Systems with Bounded Parallelism [PDF]

, 2006
This paper presents a general framework for modelling with membrane systems that is based on a computational paradigm where rules have associated a finite set of attributes and a corresponding function.
Bernardini, Francesco, Gheorghe, Marian, Pérez Jiménez, Mario de Jesús, Romero Campero, Francisco José   +3 more
core   +1 more source

Phenazine‐Based Synthetic Biology to Signal Between Cells and Electrodes

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Bioelectronic systems that enable seamless communication between electronic devices and living systems represent a transformative frontier in biotechnology. Among available methodologies, redox based signaling offers unique advantages due to its ubiquity in biology and compatibility with standard electrochemical equipment, expanding on ...
Eric VanArsdale, Monica Chu, Sally Wang, Divya Muthusamy, Eric Wold, Yi Liu, G. F. Payne, Tanya Tschirhart, W. E. Bentley   +8 more
wiley   +1 more source

Molecular radio jamming: autoinducer analogs.

Chemistry & biology, 2003
Synthesis of an N-acyl-homoserine lactone (N-acyl-HSL) analog library yields agonists and antagonists of the Pseudomonas aeruginosa quorum-sensing system. Active compounds also reveal heterogeneity in the lactone ring binding pockets of N-acyl-HSL-activated transcription factors.
openaire   +2 more sources