Results 61 to 70 of about 7,703 (178)

Natural Lactone‐Based Quorum Sensing Inhibitors Attenuate Virulence in Pseudomonas aeruginosa

Chemistry &Biodiversity, Volume 23, Issue 9, September 2026.
Targeting bacterial communication, lab‐generated lactones (Lx) inhibited biofilm formation and eliminated mature biofilms within 24–48 h. Lx treatment also suppressed pyocyanin and rhamnolipid production while downregulating rhlR expression, highlighting their promise as potent quorum‐sensing (QS) inhibitors and next‐generation antibiofilm therapeutics.
Shivani Chaturvedi, Ashutosh Sharma, Tanisha Singh, Bibhuti Bhusan Das, Tanmay Dutta, Sunil Kumar Khare   +5 more
wiley   +1 more source

Impeding Quorum Sensing Among the Intestinal Microbiota Impacts the Metastatic Rate of Colorectal Cancer

Cancer Medicine
Background The gut microbiota is associated with colorectal cancer (CRC) risk and CRC metastatic potential. However, the role of bacteria in CRC progression and metastasis remains unclear. Aims Here, we hypothesized that microbial communication, mediated
Matthew Dietz, Travis J. Gates, Rakesh Sikdar, Subbaya Subramanian, Mikael H. Elias, Christopher Staley   +5 more
doaj   +1 more source

Microbiome‐mediated chemical communication in insects: Implications for pest management

Pest Management Science, Volume 82, Issue 9, Page 8132-8151, September 2026.
Microbiome–semiochemical interactions involve the following processes: direct microbial synthesis, host gene regulation, precursor biotransformation, microbiome modulation and indirect ecological signaling. Abstract Insects rely on semiochemicals to regulate aggregation, mating, foraging, and host selection. This review synthesizes evidence that insect‐
Ioannis Eleftherianos, Wei Zhang, Amr Mohamed, Rasha K. Al‐Akeel, Abeer M. Alkhaibari, Nemat Keyhani, Guy Smagghe   +6 more
wiley   +1 more source

Phytochemical Composition, In Vitro Antioxidant, Antibacterial, and Antibiofilm Activities of Thymus vulgaris Essential Oil From Tiaret, Algeria

Chemistry &Biodiversity, Volume 23, Issue 8, August 2026.
Thymus vulgaris essential oil (TvEO), largely composed of thymol, showed strong bactericidal activity with Staphylococcus aureus (S. aureus) being most sensitive. TvEO markedly inhibited MRSA biofilm formation and significantly reduced established biofilms. Molecular docking suggests several TvEO components interact with proteins involved in S.
Soumia Dakhouche, Mouna Mnif, Sami Mnif
wiley   +1 more source

Effect of autoinducer-2 on biofilm formation of mixed strains derived from kefir

Food Chemistry: X
The mechanisms underlying kefir grain formation remain to be elucidated. Quorum sensing is a new direction for investigating this process. To explore the formation mechanism of kefir grain through quorum sensing, it is first necessary to establish its ...
Zhiying Zhang, Changkang Xu, Ying Bai
doaj   +1 more source

Bacterial–Fungal Interactions in the Kelp Endomicrobiota Drive Autoinducer-2 Quorum Sensing

Frontiers in Microbiology, 2019
Brown macroalgae are an essential component of temperate coastal ecosystems and a growing economic sector. They harbor diverse microbial communities that regulate algal development and health.
Anne Tourneroche, Raphaël Lami, Cédric Hubas, Elodie Blanchet, Marine Vallet, Karine Escoubeyrou, Alain Paris, Soizic Prado   +7 more
doaj   +1 more source

Less is more: the lack of autoinducer-2-dependent quorum sensing promotes competitive fitness of Escherichia coli strain 83972

Frontiers in Cellular and Infection Microbiology
Autoinducer-2 is a signaling molecule involved in quorum sensing in Escherichia coli. Quorum sensing enables coordinated behavior based on cell density and helps bacteria adapt to their environment.
Marla Keizers, Krishnendu Mukherjee, Michael Berger, Ulrich Dobrindt   +3 more
doaj   +1 more source

Autoinducers Act as Biological Timers in Vibrio harveyi

PLoS ONE, 2012
Quorum sensing regulates cell density-dependent phenotypes and involves the synthesis, excretion and detection of so-called autoinducers. Vibrio harveyi strain ATCC BAA-1116 (recently reclassified as Vibrio campbellii), one of the best-characterized model organisms for the study of quorum sensing, produces and responds to three autoinducers.
Anetzberger, C., Reiger, M., Fekete, A., Schell, U., Stambrau, N., Plener, L., Kopka, J., Schmitt-Kopplin, P., Hilbi, H., Jung, K.   +9 more
openaire   +5 more sources

Interference With Quorum-Sensing Signal Biosynthesis as a Promising Therapeutic Strategy Against Multidrug-Resistant Pathogens

Frontiers in Cellular and Infection Microbiology, 2019
Faced with the global health threat of increasing resistance to antibiotics, researchers are exploring interventions that target bacterial virulence factors.
Osmel Fleitas Martínez, Osmel Fleitas Martínez, Pietra Orlandi Rigueiras, Állan da Silva Pires, William Farias Porto, William Farias Porto, William Farias Porto, Osmar Nascimento Silva, Cesar de la Fuente-Nunez, Cesar de la Fuente-Nunez, Cesar de la Fuente-Nunez, Cesar de la Fuente-Nunez, Cesar de la Fuente-Nunez, Octavio Luiz Franco, Octavio Luiz Franco, Octavio Luiz Franco   +15 more
doaj   +1 more source

Cooperation and competition shape ecological resistance during periodic spatial disturbance of engineered bacteria

Scientific Reports, 2017
Cooperation is fundamental to the survival of many bacterial species. Previous studies have shown that spatial structure can both promote and suppress cooperation.
Cortney E. Wilson, Allison J. Lopatkin, Travis J. A. Craddock, William W. Driscoll, Omar Tonsi Eldakar, Jose V. Lopez, Robert P. Smith   +6 more
doaj   +1 more source