Results 21 to 30 of about 7,703 (178)

N-acyl Homoserine Lactone-Producing Pseudomonas putida Strain T2-2 from Human Tongue Surface

Sensors, 2013
Bacterial cell-to-cell communication (quorum sensing) refers to the regulation of bacterial gene expression in response to changes in microbial population density.
Yeun Mun Choo, Kok-Gan Chan, Wai-Fong Yin, Kok Keng Tee, Shenyang Chin, Jian-Woon Chen   +5 more
doaj   +1 more source

Chemical Inhibition of Pyocyanin Biosynthesis Attenuates Virulence of Pseudomonas aeruginosa

Angewandte Chemie, EarlyView.
Anti‐virulence strategies disarm pathogens rather than killing them directly. A β‐lactone reduces pyocyanin production without affecting growth. Chemical proteomics identified PqsC as the primary target via binding to Cys129. Crystallography revealed the binding mode, and SAR yielded a chloroacetamide inhibitor with improved enzymatic potency and anti ...
Wei Ding, Sebastian R. Borgert, Wulf Blankenfeldt, Stephan A. Sieber   +3 more
wiley   +2 more sources

Ecological feedback in quorum-sensing microbial populations can induce heterogeneous production of autoinducers

eLife, 2017
Autoinducers are small signaling molecules that mediate intercellular communication in microbial populations and trigger coordinated gene expression via ‘quorum sensing’.
Matthias Bauer, Johannes Knebel, Matthias Lechner, Peter Pickl, Erwin Frey   +4 more
doaj   +1 more source

Frequency modulation of a bacterial quorum sensing response

Nature Communications, 2022
Quorum-sensing bacteria produce and secrete autoinducers that trigger a behavioral change in the population when reaching a certain threshold. Here, Bettenworth et al.
Vera Bettenworth, Simon van Vliet, Bartosz Turkowyd, Annika Bamberger, Heiko Wendt, Matthew McIntosh, Wieland Steinchen, Ulrike Endesfelder, Anke Becker   +8 more
doaj   +1 more source

PtrA is functionally intertwined with GacS in regulating the biocontrol activity of Pseudomonas chlororaphis PA23

Frontiers in Microbiology, 2016
In vitro inhibition of the fungal pathogen Sclerotinia sclerotiorum by Pseudomonas chlororaphis PA23 is reliant upon a LysR-type transcriptional regulator (LTTR) called PtrA. In the current study, we show that Sclerotinia stem rot and leaf infection are
Nidhi Shah, Natasha Klaponski, Carrie Selin, Rachel Rudney, DILANTHA FERNANDO, Mark Findlay Belmonte, Teresa Rebecca De Kievit   +6 more
doaj   +1 more source

Core Principles of Bacterial Autoinducer Systems [PDF]

Microbiology and Molecular Biology Reviews, 2015
SUMMARY Autoinduction (AI), the response to self-produced chemical signals, is widespread in the bacterial world. This process controls vastly different target functions, such as luminescence, nutrient acquisition, and biofilm formation, in different ways and integrates additional environmental and physiological cues.
Burkhard A. Hense, Martin Schuster
openaire   +3 more sources

Bakteri Endofit Penghasil AHL-Laktonase Asal Tanaman Pisang untuk Pengendalian Penyakit Darah

Jurnal Fitopatologi Indonesia
Penyakit darah yang disebabkan oleh Ralstonia solanacearum Phylotype IV merupakan penyakit penting pada pisang yang menyebabkan kehilangan hasil hingga 100%. Bakteri R.
Anugrawati Abidin, Giyanto, Abdjad Asih Nawangsih   +2 more
doaj   +1 more source

Black Queen Hypothesis, partial privatization, and quorum sensing evolution.

PLoS ONE, 2022
Microorganisms produce costly cooperative goods whose benefit is partially shared with nonproducers, called 'mixed' goods. The Black Queen Hypothesis predicts that partial privatization has two major evolutionary implications.
Lucas Santana Souza, Yasuhiko Irie, Shigetoshi Eda   +2 more
doaj   +2 more sources

Detection of AI-2 Receptors in Genomes of <em>Enterobacteriaceae </em>Suggests a Role of Type-2 Quorum Sensing in Closed Ecosystems

Sensors, 2012
The LuxS enzyme, an S-ribosyl-homocysteine lyase, catalyzes the production of the signal precursor for autoinducer-2 mediated quorum sensing (QS-2) in <em>Vibrio</em>.
Brion Duffy, Fabio Rezzonico, Theo H. M. Smits   +2 more
doaj   +1 more source

Plant-Derived Natural Products as Sources of Anti-Quorum Sensing Compounds

Sensors, 2013
Quorum sensing is a system of stimuli and responses in relation to bacterial cell population density that regulates gene expression, including virulence determinants. Consequently, quorum sensing has been an attractive target for the development of novel
Kok-Gan Chan, Yee Meng Chong, Thiba Krishnan, Li Ying Tan, Wai-Fong Yin, Choon-Kook Sam, Chong-Lek Koh   +6 more
doaj   +1 more source