Results 11 to 20 of about 27,529 (230)
Autoimmunity, Autoinflammation, and Infection in Uveitis [PDF]
American Journal of Ophthalmology, 2018 Funding/Support: No funding or grant support. Financial Disclosures: John V. Forrester has received an honorarium for lecturing from Janssen (London, UK). Lucia Kuffova has undertaken consultancy work for Abbvie (London, UK). Andrew D.
Dick, Andrew D. +2 more
core +10 more sources
JAK inhibitors in autoinflammation [PDF]
Journal of Clinical Investigation, 2018 Interferonopathies are a subset of autoinflammatory disorders with a prominent type I IFN gene signature. Treatment of these patients has been challenging, given the lack of response to common autoinflammatory therapeutics including IL-1 and TNF blockade.
Hal M, Hoffman, Lori, Broderick
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The everchanging framework of autoinflammation [PDF]
Internal and Emergency Medicine, 2021 AbstractThe innate immunity works as a defence bullwark that safeguards healthy tissues with the power of detecting infectious agents in the human body: errors in the context of innate immunity identify autoinflammatory disorders (AIDs), which arise as bouts of aberrant inflammation with little or no involvement of T and B cells and neither recognized ...
Manna R, Rigante D
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Frontiers in Immunology, 2022 Autoinflammatory diseases are a group of clinical syndromes characterized by constitutive overactivation of innate immune pathways. This results in increased production of or responses to monocyte- and neutrophil-derived cytokines such as interleukin-1β (
McKella Sylvester +2 more
doaj +1 more source
Modern concept of autoimmunity in rheumatology
Научно-практическая ревматология, 2023 Two fundamental pathologic processes are central to the spectrum of chronic inflammation mechanisms: autoimmunity and autoinflammation. Autoimmunity and autoinflammation are mutually potent pathologic processes; their development is considered within the
E. L. Nasonov
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Living with autoinflammatory diseases: identifying unmet needs of children, adolescents and adults
Pediatric Rheumatology Online Journal, 2018 Background Autoinflammatory diseases (AIDs) illnesses of the innate immunity resulting in clinical signs and symptoms of systemic inflammation and loss of organ functions.
Gabriele Erbis +6 more
doaj +1 more source
Autoinflammatory keratinization diseases: The concept, diseases involved, and pathogeneses
Dermatologica Sinica, 2022 As predisposing factors and pathogenic mechanisms of inflammatory keratinization disorders of the skin have become increasingly elucidated in recent years, a number of inflammatory keratinization disorders are now known to have the excessive activation ...
Masashi Akiyama
doaj +1 more source
Journal of Clinical Medicine, 2021 In recent years, we have entered a new era full of insights into exciting pathways and improved management of a distinct class of inflammatory conditions [...]
openaire +2 more sources
Alʹmanah Kliničeskoj Mediciny, 2018 The paper demonstrates current opportunities of effective management of periodic disease as an autoinflammatory disorder based on a clinical case of colchicine-resistant Mediterranean fever. We present modern approaches to the autoinflammation hypothesis
V. V. Rameev +3 more
doaj +1 more source
The burgeoning field of innate immune-mediated disease and autoinflammation. [PDF]
, 2016 Immune-mediated autoinflammatory diseases are occupying an increasingly prominent position among the pantheon of debilitating conditions that afflict mankind.
McDermott, MF +3 more
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