Results 201 to 210 of about 27,529 (230)
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Inflammasomes and Autoinflammation
2019Inflammasomes are large intracellular multi-protein polymeric complexes comprised of sensors, adaptor proteins and caspases. As innate immune sensors capable of recognizing and rapidly responding to pathogen and metabolic danger signals, inflammasomes act as key modulators of initial immune responses.
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Urticarial Syndromes and Autoinflammation
2010Recent genetic studies of urticaria have revealed distinct molecular pathways underlying different types of urticaria, and have defined several urticarial syndromes associated with autoinflammation. Although the cutaneous presentation of urticarial syndromes is strikingly similar, many of these syndromes involve diverse features of systemic ...
Kanade Shinkai, Kieron S. Leslie
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S100 Proteins in Autoinflammation
2019Among the putative markers for autoinflammatory diseases, studies on phagocyte-derived S100 proteins (S100A8/A9, S100A12: calgranulins) are the most advanced to date. Translational studies have suggested an important role for these danger-associated molecular pattern (DAMP) molecules as robust inflammation biomarkers.
Dirk Holzinger +2 more
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The Journal of Allergy and Clinical Immunology: In Practice
Daniel L, Rosenberg, Harold M, Hoffman
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Daniel L, Rosenberg, Harold M, Hoffman
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Human TBK1 deficiency leads to autoinflammation driven by TNF-induced cell death
Cell, 2021Justin Taft +2 more
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Autoinflammation and autoimmunity across rheumatic and musculoskeletal diseases
Nature Reviews Rheumatology, 2021Zoltan Szekanecz +2 more
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ADAR1 prevents autoinflammation by suppressing spontaneous ZBP1 activation
Nature, 2022Richard de Reuver +2 more
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Inflammation, Autoinflammation and Autoimmunity in Inflammatory Bowel Diseases
Current Issues in Molecular Biology, 2023Giulia Musso +2 more
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