Results 191 to 200 of about 27,529 (230)
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Infektion oder Autoinflammation?
MMW - Fortschritte der Medizin, 2016Geht akuter Durchfall mit Fieber und/oder Erbrechen einher, ist der „Normalfall“ eine Magen-Darm-Infektion durch Viren, Bakterien oder bakterielle Toxine. Als Ausloser kommen aber auch autoinflammatorische Pathologien infrage, wie chronisch-entzundliche Darmerkrankungen und die angeborenen hereditaren rekurrierenden Fiebersyndrome.
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Autoinflammation und Autoimmunität
Arthritis und Rheuma, 2014ZusammenfassungAutoinflammation wird definiert als selbstgerichtete Entzündung, bei der lokale Faktoren zu einer Aktivierung von Zellen des angeborenen Immunsystems führen, mit der Folge einer Schädigung des lokalen Gewebes, die aber auch von einer generalisierten Entzündungsreaktion mit Fieber begleitet sein kann.
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Proteasomes in Autoinflammation
2019The cellular proteostasis network integrates all signals controlling protein synthesis, folding, trafficking, and clearance machineries in multiple subcellular compartments to maintain the integrity of the proteome and to ensure the survival of cells and tissues under varying proteotoxic insults.
Anja Brehm +2 more
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2019
Autoinflammatory diseases represent an expanding spectrum of diseases characterized by recurrent episodes of fever and systemic inflammation, due to disorders of innate immunity. Since the concept of autoinflammation was first affirmed in 1999 to define TNF-receptor associated periodic syndrome (TRAPS), many other monogenic autoinflammatory diseases ...
Angela Rösen-Wolff, Anna Rubartelli
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Autoinflammatory diseases represent an expanding spectrum of diseases characterized by recurrent episodes of fever and systemic inflammation, due to disorders of innate immunity. Since the concept of autoinflammation was first affirmed in 1999 to define TNF-receptor associated periodic syndrome (TRAPS), many other monogenic autoinflammatory diseases ...
Angela Rösen-Wolff, Anna Rubartelli
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Broadening the definition of autoinflammation
Seminars in Immunopathology, 2015Initially, the concept of autoinflammation posited that there be no involvement of autoreactive B or T cells, and no evidence of infection. These criteria served well to help establish the concept, and distinguish autoinflammatory diseases from autoimmune or infectious conditions.
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Epigenetics in Autoinflammation
2019The molecular mechanisms of inflammation involve a series of processes that start as extracellular signals that interact with membrane-bound receptors, cell signaling cascades, nuclear factors, and epigenetic enzymes that activate a specific gene expression program.
Clara Lorente-Sorolla +2 more
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Autoinflammation und pustulöse Psoriasis
Kompass Dermatologie, 2022Pustular psoriasis is a chronic inflammatory skin disease characterized by erythematous plaques with sterile pustules. It includes the distinct clinical entities generalized pustular psoriasis (GPP), acrodermatitis continua of Hallopeau (ACH) and palmoplantar pustular psoriasis (PPPP).
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Autoinflammation and autoimmunity: Bridging the divide
Autoimmunity Reviews, 2012As soon as autoinflammatory diseases (AIDs) emerged as new entities, they have been linked to the well known world of autoimmunity. In fact, AIDs and systemic autoimmune diseases (ADs), share some characteristics: they start with the prefix "auto" to define a pathological process directed against self; they are systemic diseases, frequently involving ...
DORIA, ANDREA +8 more
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Autoinflammation and Autoimmunity
2019The elucidation of the genetic basis for hereditary recurrent fever syndromes validated the role of innate immune dysregulation in diseases formerly viewed as autoimmune. Recognizing the non-autoimmune nature of tumor necrosis factor receptor-associated periodic syndrome (TRAPS), one such syndrome, and the lack of evidence for autoantibodies or B- or T-
Dennis McGonagle, Abdulla Watad
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Autoimmunity versus Autoinflammation - Friend or Foe?
Wiener Medizinische Wochenschrift, 2014"Autoimmunity" is a designation dependent on the conventional immunological issue of self/non-self discrimination. Identification of novel target autoantigens is still an important issue ongoing in classical tissue-specific autoimmune bullous diseases and autoimmune connective tissue diseases.
Nobuo, Kanazawa +2 more
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