Results 221 to 230 of about 171,535 (264)
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Immunology Letters, 2014
Autoinflammatory diseases represent an expanding spectrum of genetic and non-genetic inflammatory diseases characterized by recurrent episodes of fever and systemic inflammation affecting the eyes, joints, skin, and serosal surfaces. Thus, these syndromes are recognized as disorders of innate immunity.
Anna Rubartelli
exaly +4 more sources
Autoinflammatory diseases represent an expanding spectrum of genetic and non-genetic inflammatory diseases characterized by recurrent episodes of fever and systemic inflammation affecting the eyes, joints, skin, and serosal surfaces. Thus, these syndromes are recognized as disorders of innate immunity.
Anna Rubartelli
exaly +4 more sources
, 2018 This book discusses the role of the microbiome in rheumatic diseases and details its implications for patient treatment. Recently, with technological advances, there has been significant research into the microbiome. This has enabled us to more profoundly understand its role in our immune system maturation as well as the role played by microorganisms ...
Rigante D., Vitale A., Cantarini L.
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Clinical and experimental rheumatology, 2006 The autoinflammatory disorders are a new and expanding classification of inflammatory diseases characterized by recurrent episodes of systemic inflammation in the absence of pathogens, autoantibodies or antigen specific T cells. These disorders are caused by primary dysfunction of the innate immune system, without evidence of adaptive immune ...
GALEAZZI M +10 more
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Pediatric Clinics of North America, 2012
There has been an expansion of the autoinflammatory syndromes due to the discovery of new diseases related to mutations in genes regulating the innate immune system and the knowledge gained from these diseases as applied to more common nongenetic inflammatory conditions.
Philip J, Hashkes, Ori, Toker
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There has been an expansion of the autoinflammatory syndromes due to the discovery of new diseases related to mutations in genes regulating the innate immune system and the knowledge gained from these diseases as applied to more common nongenetic inflammatory conditions.
Philip J, Hashkes, Ori, Toker
openaire +2 more sources
The autoinflammatory syndromes
Current Opinion in Allergy and Clinical Immunology, 2002To review the remarkable recent progress in our understanding of a range of inflammatory conditions in humans that until recently appeared unrelated. The term autoinflammatory disease has been proposed to describe a group of disorders characterized by attacks of seemingly unprovoked inflammation without significant levels of autoantibodies and ...
Michael F, McDermott +1 more
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Update on autoinflammatory diseases
Current Opinion in Rheumatology, 2023Purpose of review Although the concept of systemic autoinflammatory diseases (SAIDs) is still very young, our knowledge about them is exponentially growing. In the current review, we aim to discuss novel SAIDs and autoinflammatory pathways discovered in the last couple of years. Recent findings
Kosar Asna, Ashari +2 more
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Best Practice & Research Clinical Rheumatology, 2008
Autoinflammatory diseases (AIDs) are illnesses caused by primary dysfunction of the innate immune system. Proteins that are mutated in AIDs mediate the regulation of NFkappaB activation, cell apoptosis, and IL-1beta secretion through cross-regulated and sometimes common signaling pathways.
Touitou, I., Kone-Paut, I.
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Autoinflammatory diseases (AIDs) are illnesses caused by primary dysfunction of the innate immune system. Proteins that are mutated in AIDs mediate the regulation of NFkappaB activation, cell apoptosis, and IL-1beta secretion through cross-regulated and sometimes common signaling pathways.
Touitou, I., Kone-Paut, I.
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Inherited Autoinflammatory Syndromes
Annual Review of Pathology: Mechanisms of Disease, 2022Autoinflammation describes a collection of diverse diseases caused by indiscriminate activation of the immune system in an antigen-independent manner. The rapid advancement of genetic diagnostics has allowed for the identification of a wide array of monogenic causes of autoinflammation.
Julia E, Rood, Edward M, Behrens
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Acta Clinica Belgica, 2006
Autoinflammatory diseases can be specified as inborn errors of the innate immune system. The main component of autoinflammatory diseases is the group of hereditary periodic fevers which are characterised by intermittent bouts of clinical inflammation with focal organ involvement mainly: abdomen, musculoskeletal system and skin. The most frequent one is
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Autoinflammatory diseases can be specified as inborn errors of the innate immune system. The main component of autoinflammatory diseases is the group of hereditary periodic fevers which are characterised by intermittent bouts of clinical inflammation with focal organ involvement mainly: abdomen, musculoskeletal system and skin. The most frequent one is
openaire +3 more sources
Treatment of autoinflammatory syndromes
Current Opinion in Pediatrics, 2010Inherited autoinflammatory diseases are experiments in nature in which mutations of proteins playing a pivotal role in the regulation of the innate immunity lead to unprovoked episodes of inflammation. The understanding of the molecular pathways involved in these disorders has shed a new light on the pattern of activation and maintenance of the ...
Gattorno M, MARTINI, ALBERTO
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