Results 21 to 30 of about 171,535 (264)
An Update on Autoinflammatory Diseases [PDF]
Current Medicinal Chemistry, 2013 Autoinflammatory diseases area group of clinical conditions other than autoimmune diseases, characterized by recurrent inflammatory episodes. From apathogenetic point of view they are determined by a dys regulation of innate immunity, without involvement of specific immunity (auto reactive T cells and auto antibodies). Recently, the increased knowledge
Ciccarelli F +2 more
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Interleukin‐18 signaling promotes activation of hepatic stellate cells in mouse liver fibrosis
Hepatology, EarlyView., 2022 Interleukin‐18 signaling promotes activation of hepatic stellate cells in mouse liver fibrosis. Abstract Background and Aims Nucleotide‐binding oligomerization domain‐like receptor‐family pyrin domain‐containing 3 (NLRP3) inflammasome activation has been shown to result in liver fibrosis.
Jana Knorr +19 more
wiley +1 more source
Rheumato, 2023 Three years after its emergence, coronavirus disease 2019 (COVID-19) continues to be a leading cause of worldwide morbidity and mortality. This systematic review comprises relevant case reports that discuss non-multisystem inflammatory syndrome in ...
Antoine Fakhry AbdelMassih +26 more
doaj +1 more source
Frontiers in Immunology, 2018 TNFAIP3 encodes the NF-κB regulatory protein A20. High-penetrance heterozygous mutations in TNFAIP3 cause a haploinsufficiency of A20 (HA20), inadequate inhibition of NF-κB pathway, and an early onset autoinflammatory disorder.
Dylan Lawless +6 more
doaj +1 more source
Autoinflammatory Syndromes [PDF]
Dermatologic Clinics, 2013 Autoinflammatory syndromes comprise a diagnostically challenging group of systemic inflammatory disorders uniquely related by (1) dysregulation of innate immunity, (2) inflammasome activation, (3) dramatic clinical features (high fevers, neutrophilic rashes, and bone or synovial involvement), (4) impressive acute phase responses, and (5) effective ...
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Paraproteinemia in Autoinflammatory Diseases
, 2022 Autoinflammatory diseases represent clinical entities characterized by recurrent episodes of systemic and organ-specific inflammation determined by the primary deregulation of the innate immune system.
Vitale A., Cantarini L.
core +1 more source
Autoinflammatory Features in Gouty Arthritis [PDF]
, 2021 In the panorama of inflammatory arthritis, gout is the most common and studied disease. It is known that hyperuricemia and monosodium urate (MSU) crystal-induced inflammation provoke crystal deposits in joints.
Sara Bindoli +9 more
core +1 more source
Clinical & Translational Immunology, 2021 FIRES (febrile infection‐related epilepsy syndrome) is a protracted neuroinflammatory condition of obscure cause. It mainly afflicts school‐age children and often leads to permanent neurological sequelae.
Wei‐Sheng Lin, Ting‐Rong Hsu
doaj +1 more source
Autoinflammatory disease in the lung [PDF]
Immunology, 2018 SummaryAscertaining the dominant cell type driving an immunological disease is essential to understanding the causal pathology and, therefore, selecting or developing an effective treatment. Classifying immunological diseases in this way has led to successful treatment regimens for many monogenic diseases; however, when the dominant cell type is ...
Scambler, T +4 more
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Chronic recurrent multifocal osteomyelitis. A narrative and pictorial review
Frontiers in Immunology, 2022 Chronic recurrent and multifocal osteomyelitis (CRMO) is a nonsporadic autoinflammatory disorder. Currently, it is diagnosed based on clinical, radiologic, pathological, and longitudinal data.
Consolato M. Sergi +6 more
doaj +1 more source